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254 related items for PubMed ID: 19147682

  • 1. In conditions of limited chromophore supply rods entrap 11-cis-retinal leading to loss of cone function and cell death.
    Samardzija M, Tanimoto N, Kostic C, Beck S, Oberhauser V, Joly S, Thiersch M, Fahl E, Arsenijevic Y, von Lintig J, Wenzel A, Seeliger MW, Grimm C.
    Hum Mol Genet; 2009 Apr 01; 18(7):1266-75. PubMed ID: 19147682
    [Abstract] [Full Text] [Related]

  • 2. Cone opsin mislocalization in Rpe65-/- mice: a defect that can be corrected by 11-cis retinal.
    Rohrer B, Lohr HR, Humphries P, Redmond TM, Seeliger MW, Crouch RK.
    Invest Ophthalmol Vis Sci; 2005 Oct 01; 46(10):3876-82. PubMed ID: 16186377
    [Abstract] [Full Text] [Related]

  • 3. R91W mutation in Rpe65 leads to milder early-onset retinal dystrophy due to the generation of low levels of 11-cis-retinal.
    Samardzija M, von Lintig J, Tanimoto N, Oberhauser V, Thiersch M, Remé CE, Seeliger M, Grimm C, Wenzel A.
    Hum Mol Genet; 2008 Jan 15; 17(2):281-92. PubMed ID: 17933883
    [Abstract] [Full Text] [Related]

  • 4. Trafficking of membrane-associated proteins to cone photoreceptor outer segments requires the chromophore 11-cis-retinal.
    Zhang H, Fan J, Li S, Karan S, Rohrer B, Palczewski K, Frederick JM, Crouch RK, Baehr W.
    J Neurosci; 2008 Apr 09; 28(15):4008-14. PubMed ID: 18400900
    [Abstract] [Full Text] [Related]

  • 5. Pharmacological Amelioration of Cone Survival and Vision in a Mouse Model for Leber Congenital Amaurosis.
    Li S, Samardzija M, Yang Z, Grimm C, Jin M.
    J Neurosci; 2016 May 25; 36(21):5808-19. PubMed ID: 27225770
    [Abstract] [Full Text] [Related]

  • 6. RPE65 is essential for the function of cone photoreceptors in NRL-deficient mice.
    Wenzel A, von Lintig J, Oberhauser V, Tanimoto N, Grimm C, Seeliger MW.
    Invest Ophthalmol Vis Sci; 2007 Feb 25; 48(2):534-42. PubMed ID: 17251447
    [Abstract] [Full Text] [Related]

  • 7. RDH12 allows cone photoreceptors to regenerate opsin visual pigments from a chromophore precursor to escape competition with rods.
    Kaylor JJ, Frederiksen R, Bedrosian CK, Huang M, Stennis-Weatherspoon D, Huynh T, Ngan T, Mulamreddy V, Sampath AP, Fain GL, Travis GH.
    Curr Biol; 2024 Aug 05; 34(15):3342-3353.e6. PubMed ID: 38981477
    [Abstract] [Full Text] [Related]

  • 8. Loss of cone photoreceptors caused by chromophore depletion is partially prevented by the artificial chromophore pro-drug, 9-cis-retinyl acetate.
    Maeda T, Cideciyan AV, Maeda A, Golczak M, Aleman TS, Jacobson SG, Palczewski K.
    Hum Mol Genet; 2009 Jun 15; 18(12):2277-87. PubMed ID: 19339306
    [Abstract] [Full Text] [Related]

  • 9. cis Retinol oxidation regulates photoreceptor access to the retina visual cycle and cone pigment regeneration.
    Sato S, Kefalov VJ.
    J Physiol; 2016 Nov 15; 594(22):6753-6765. PubMed ID: 27385534
    [Abstract] [Full Text] [Related]

  • 10. Opsin activation of transduction in the rods of dark-reared Rpe65 knockout mice.
    Fan J, Woodruff ML, Cilluffo MC, Crouch RK, Fain GL.
    J Physiol; 2005 Oct 01; 568(Pt 1):83-95. PubMed ID: 15994181
    [Abstract] [Full Text] [Related]

  • 11. Cone versus rod disease in a mutant Rpgr mouse caused by different genetic backgrounds.
    Brunner S, Skosyrski S, Kirschner-Schwabe R, Knobeloch KP, Neidhardt J, Feil S, Glaus E, Luhmann UF, Rüther K, Berger W.
    Invest Ophthalmol Vis Sci; 2010 Feb 01; 51(2):1106-15. PubMed ID: 20007830
    [Abstract] [Full Text] [Related]

  • 12. Spectral tuning by selective chromophore uptake in rods and cones of eight populations of nine-spined stickleback (Pungitius pungitius).
    Saarinen P, Pahlberg J, Herczeg G, Viljanen M, Karjalainen M, Shikano T, Merilä J, Donner K.
    J Exp Biol; 2012 Aug 15; 215(Pt 16):2760-73. PubMed ID: 22837448
    [Abstract] [Full Text] [Related]

  • 13. Vitamin A metabolism in rod and cone visual cycles.
    Saari JC.
    Annu Rev Nutr; 2012 Aug 21; 32():125-45. PubMed ID: 22809103
    [Abstract] [Full Text] [Related]

  • 14. The Consequences of Hypomorphic RPE65 for Rod and Cone Photoreceptors.
    Samardzija M, Barben M, Geiger P, Grimm C.
    Adv Exp Med Biol; 2016 Aug 21; 854():341-6. PubMed ID: 26427430
    [Abstract] [Full Text] [Related]

  • 15. Ciliary neurotrophic factor (CNTF) protects retinal cone and rod photoreceptors by suppressing excessive formation of the visual pigments.
    Li S, Sato K, Gordon WC, Sendtner M, Bazan NG, Jin M.
    J Biol Chem; 2018 Sep 28; 293(39):15256-15268. PubMed ID: 30115683
    [Abstract] [Full Text] [Related]

  • 16. Gene therapy regenerates protein expression in cone photoreceptors in Rpe65(R91W/R91W) mice.
    Kostic C, Crippa SV, Pignat V, Bemelmans AP, Samardzija M, Grimm C, Wenzel A, Arsenijevic Y.
    PLoS One; 2011 Feb 03; 6(2):e16588. PubMed ID: 21304899
    [Abstract] [Full Text] [Related]

  • 17. The visual cycle of the cone photoreceptors of the retina.
    Wolf G.
    Nutr Rev; 2004 Jul 03; 62(7 Pt 1):283-6. PubMed ID: 15384919
    [Abstract] [Full Text] [Related]

  • 18. Protection of cone photoreceptor M-opsin degradation with 9-cis-β-carotene-rich alga Dunaliella bardawil in Rpe65(-/-) mouse retinal explant culture.
    Ozaki T, Nakazawa M, Kudo T, Hirano S, Suzuki K, Ishiguro S.
    Curr Eye Res; 2014 Dec 03; 39(12):1221-31. PubMed ID: 25006880
    [Abstract] [Full Text] [Related]

  • 19. Vitamin A and Vision.
    Saari JC.
    Subcell Biochem; 2016 Dec 03; 81():231-259. PubMed ID: 27830507
    [Abstract] [Full Text] [Related]

  • 20. Effective and sustained delivery of hydrophobic retinoids to photoreceptors.
    Tang PH, Fan J, Goletz PW, Wheless L, Crouch RK.
    Invest Ophthalmol Vis Sci; 2010 Nov 03; 51(11):5958-64. PubMed ID: 20574023
    [Abstract] [Full Text] [Related]

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