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201 related items for PubMed ID: 19151380

  • 1. Mechanism of cataract formation in alphaA-crystallin Y118D mutation.
    Huang Q, Ding L, Phan KB, Cheng C, Xia CH, Gong X, Horwitz J.
    Invest Ophthalmol Vis Sci; 2009 Jun; 50(6):2919-26. PubMed ID: 19151380
    [Abstract] [Full Text] [Related]

  • 2. Arginine 54 and Tyrosine 118 residues of {alpha}A-crystallin are crucial for lens formation and transparency.
    Xia CH, Liu H, Chang B, Cheng C, Cheung D, Wang M, Huang Q, Horwitz J, Gong X.
    Invest Ophthalmol Vis Sci; 2006 Jul; 47(7):3004-10. PubMed ID: 16799046
    [Abstract] [Full Text] [Related]

  • 3. Altered chaperone-like activity of alpha-crystallins promotes cataractogenesis.
    Cheng C, Xia CH, Huang Q, Ding L, Horwitz J, Gong X.
    J Biol Chem; 2010 Dec 24; 285(52):41187-93. PubMed ID: 20959464
    [Abstract] [Full Text] [Related]

  • 4. Mechanism of insolubilization by a single-point mutation in alphaA-crystallin linked with hereditary human cataracts.
    Andley UP, Hamilton PD, Ravi N.
    Biochemistry; 2008 Sep 09; 47(36):9697-706. PubMed ID: 18700785
    [Abstract] [Full Text] [Related]

  • 5. Synergistic effects of metal ion and the pre-senile cataract-causing G98R alphaA-crystallin: self-aggregation propensities and chaperone activity.
    Singh D, Tangirala R, Bakthisaran R, Chintalagiri MR.
    Mol Vis; 2009 Oct 16; 15():2050-60. PubMed ID: 19862354
    [Abstract] [Full Text] [Related]

  • 6. A novel mutation (F71L) in alphaA-crystallin with defective chaperone-like function associated with age-related cataract.
    Bhagyalaxmi SG, Srinivas P, Barton KA, Kumar KR, Vidyavathi M, Petrash JM, Bhanuprakash Reddy G, Padma T.
    Biochim Biophys Acta; 2009 Oct 16; 1792(10):974-81. PubMed ID: 19595763
    [Abstract] [Full Text] [Related]

  • 7. A Comparative Study of the Impact of Calcium Ion on Structure, Aggregation and Chaperone Function of Human αA-crystallin and its Cataract- Causing R12C Mutant.
    Saba S, Ghahramani M, Yousefi R.
    Protein Pept Lett; 2017 Oct 16; 24(11):1048-1058. PubMed ID: 28782478
    [Abstract] [Full Text] [Related]

  • 8. The cataract-causing mutation G98R in human alphaA-crystallin leads to folding defects and loss of chaperone activity.
    Singh D, Raman B, Ramakrishna T, Rao ChM.
    Mol Vis; 2006 Nov 15; 12():1372-9. PubMed ID: 17149363
    [Abstract] [Full Text] [Related]

  • 9. αA-Crystallin-derived mini-chaperone modulates stability and function of cataract causing αAG98R-crystallin.
    Raju M, Santhoshkumar P, Sharma KK.
    PLoS One; 2012 Nov 15; 7(9):e44077. PubMed ID: 22970163
    [Abstract] [Full Text] [Related]

  • 10. Changes in relative histone abundance and heterochromatin in αA-crystallin and αB-crystallin knock-in mutant mouse lenses.
    Andley UP, Naumann BN, Hamilton PD, Bozeman SL.
    BMC Res Notes; 2020 Jul 02; 13(1):315. PubMed ID: 32616056
    [Abstract] [Full Text] [Related]

  • 11. In vivo substrates of the lens molecular chaperones αA-crystallin and αB-crystallin.
    Andley UP, Malone JP, Townsend RR.
    PLoS One; 2014 Jul 02; 9(4):e95507. PubMed ID: 24760011
    [Abstract] [Full Text] [Related]

  • 12. The IXI/V motif in the C-terminal extension of alpha-crystallins: alternative interactions and oligomeric assemblies.
    Pasta SY, Raman B, Ramakrishna T, Rao ChM.
    Mol Vis; 2004 Sep 08; 10():655-62. PubMed ID: 15448619
    [Abstract] [Full Text] [Related]

  • 13. Cataract mutation P20S of alphaB-crystallin impairs chaperone activity of alphaA-crystallin and induces apoptosis of human lens epithelial cells.
    Li H, Li C, Lu Q, Su T, Ke T, Li DW, Yuan M, Liu J, Ren X, Zhang Z, Zeng S, Wang QK, Liu M.
    Biochim Biophys Acta; 2008 May 08; 1782(5):303-9. PubMed ID: 18343237
    [Abstract] [Full Text] [Related]

  • 14. Negative charge at aspartate 151 is important for human lens αA-crystallin stability and chaperone function.
    Takata T, Matsubara T, Nakamura-Hirota T, Fujii N.
    Exp Eye Res; 2019 May 08; 182():10-18. PubMed ID: 30849387
    [Abstract] [Full Text] [Related]

  • 15. Activation of the unfolded protein response by a cataract-associated αA-crystallin mutation.
    Watson GW, Andley UP.
    Biochem Biophys Res Commun; 2010 Oct 15; 401(2):192-6. PubMed ID: 20833134
    [Abstract] [Full Text] [Related]

  • 16. A transgenic mouse model for human autosomal dominant cataract.
    Hsu CD, Kymes S, Petrash JM.
    Invest Ophthalmol Vis Sci; 2006 May 15; 47(5):2036-44. PubMed ID: 16639013
    [Abstract] [Full Text] [Related]

  • 17. AlphaA-crystallin R49Cneo mutation influences the architecture of lens fiber cell membranes and causes posterior and nuclear cataracts in mice.
    Andley UP.
    BMC Ophthalmol; 2009 Jul 20; 9():4. PubMed ID: 19619312
    [Abstract] [Full Text] [Related]

  • 18. Conformational and functional differences between recombinant human lens alphaA- and alphaB-crystallin.
    Sun TX, Das BK, Liang JJ.
    J Biol Chem; 1997 Mar 07; 272(10):6220-5. PubMed ID: 9045637
    [Abstract] [Full Text] [Related]

  • 19. Mixed oligomer formation between human alphaA-crystallin and its cataract-causing G98R mutant: structural, stability and functional differences.
    Singh D, Raman B, Ramakrishna T, Rao ChM.
    J Mol Biol; 2007 Nov 09; 373(5):1293-304. PubMed ID: 17900621
    [Abstract] [Full Text] [Related]

  • 20. Cataract-causing allele in CRYAA (Y118D) proceeds through endoplasmic reticulum stress in mouse model.
    Jia ZK, Fu CX, Wang AL, Yao K, Chen XJ.
    Zool Res; 2021 May 18; 42(3):300-309. PubMed ID: 33929105
    [Abstract] [Full Text] [Related]

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