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300 related items for PubMed ID: 19153097

  • 1. Overexpression of glutamate-cysteine ligase protects human COV434 granulosa tumour cells against oxidative and gamma-radiation-induced cell death.
    Cortes-Wanstreet MM, Giedzinski E, Limoli CL, Luderer U.
    Mutagenesis; 2009 May; 24(3):211-24. PubMed ID: 19153097
    [Abstract] [Full Text] [Related]

  • 2. Minimal ovarian upregulation of glutamate cysteine ligase expression in response to suppression of glutathione by buthionine sulfoximine.
    Hoang YD, Avakian AP, Luderer U.
    Reprod Toxicol; 2006 Feb; 21(2):186-96. PubMed ID: 16183247
    [Abstract] [Full Text] [Related]

  • 3. Follicle-stimulating hormone and estradiol interact to stimulate glutathione synthesis in rat ovarian follicles and granulosa cells.
    Hoang YD, Nakamura BN, Luderer U.
    Biol Reprod; 2009 Oct; 81(4):636-46. PubMed ID: 19516019
    [Abstract] [Full Text] [Related]

  • 4. Differential regulation of glutamate-cysteine ligase subunit expression and increased holoenzyme formation in response to cysteine deprivation.
    Lee JI, Kang J, Stipanuk MH.
    Biochem J; 2006 Jan 01; 393(Pt 1):181-90. PubMed ID: 16137247
    [Abstract] [Full Text] [Related]

  • 5. Manipulation of cellular GSH biosynthetic capacity via TAT-mediated protein transduction of wild-type or a dominant-negative mutant of glutamate cysteine ligase alters cell sensitivity to oxidant-induced cytotoxicity.
    Backos DS, Brocker CN, Franklin CC.
    Toxicol Appl Pharmacol; 2010 Feb 15; 243(1):35-45. PubMed ID: 19914271
    [Abstract] [Full Text] [Related]

  • 6. Gonadotropin regulation of glutamate cysteine ligase catalytic and modifier subunit expression in rat ovary is subunit and follicle stage specific.
    Tsai-Turton M, Luderer U.
    Am J Physiol Endocrinol Metab; 2005 Sep 15; 289(3):E391-402. PubMed ID: 15811874
    [Abstract] [Full Text] [Related]

  • 7. Impaired synthesis and antioxidant defense of glutathione in the cerebellum of autistic subjects: alterations in the activities and protein expression of glutathione-related enzymes.
    Gu F, Chauhan V, Chauhan A.
    Free Radic Biol Med; 2013 Dec 15; 65():488-496. PubMed ID: 23892356
    [Abstract] [Full Text] [Related]

  • 8. TGFbeta1-induced suppression of glutathione antioxidant defenses in hepatocytes: caspase-dependent post-translational and caspase-independent transcriptional regulatory mechanisms.
    Franklin CC, Rosenfeld-Franklin ME, White C, Kavanagh TJ, Fausto N.
    FASEB J; 2003 Aug 15; 17(11):1535-7. PubMed ID: 12824300
    [Abstract] [Full Text] [Related]

  • 9. Variable regulation of glutamate cysteine ligase subunit proteins affects glutathione biosynthesis in response to oxidative stress.
    Krzywanski DM, Dickinson DA, Iles KE, Wigley AF, Franklin CC, Liu RM, Kavanagh TJ, Forman HJ.
    Arch Biochem Biophys; 2004 Mar 01; 423(1):116-25. PubMed ID: 14871475
    [Abstract] [Full Text] [Related]

  • 10. Initial characterization of the glutamate-cysteine ligase modifier subunit Gclm(-/-) knockout mouse. Novel model system for a severely compromised oxidative stress response.
    Yang Y, Dieter MZ, Chen Y, Shertzer HG, Nebert DW, Dalton TP.
    J Biol Chem; 2002 Dec 20; 277(51):49446-52. PubMed ID: 12384496
    [Abstract] [Full Text] [Related]

  • 11. Glutamate cysteine ligase (GCL) transgenic and gene-targeted mice for controlling glutathione synthesis.
    Mohar I, Botta D, White CC, McConnachie LA, Kavanagh TJ.
    Curr Protoc Toxicol; 2009 Feb 20; Chapter 6():Unit6.16. PubMed ID: 23045016
    [Abstract] [Full Text] [Related]

  • 12. Glutamate cysteine ligase catalysis: dependence on ATP and modifier subunit for regulation of tissue glutathione levels.
    Chen Y, Shertzer HG, Schneider SN, Nebert DW, Dalton TP.
    J Biol Chem; 2005 Oct 07; 280(40):33766-74. PubMed ID: 16081425
    [Abstract] [Full Text] [Related]

  • 13. Localization of glutamate cysteine ligase subunit mRNA within the rat ovary and relationship to follicular apoptosis.
    Luderer U, Diaz D, Faustman EM, Kavanagh TJ.
    Mol Reprod Dev; 2003 Jul 07; 65(3):254-61. PubMed ID: 12784246
    [Abstract] [Full Text] [Related]

  • 14. Gonadotropin regulation of glutathione synthesis in the rat ovary.
    Luderer U, Kavanagh TJ, White CC, Faustman EM.
    Reprod Toxicol; 2001 Jul 07; 15(5):495-504. PubMed ID: 11780957
    [Abstract] [Full Text] [Related]

  • 15. Utilization of 6-(methylsulfinyl)hexyl isothiocyanate for sensitization of tumor cells to antitumor agents in combination therapies.
    Yamaguchi H, Kidachi Y, Kamiie K, Noshita T, Umetsu H, Fuke Y, Ryoyama K.
    Biochem Pharmacol; 2013 Aug 15; 86(4):458-68. PubMed ID: 23791871
    [Abstract] [Full Text] [Related]

  • 16. Knockout of the mouse glutamate cysteine ligase catalytic subunit (Gclc) gene: embryonic lethal when homozygous, and proposed model for moderate glutathione deficiency when heterozygous.
    Dalton TP, Dieter MZ, Yang Y, Shertzer HG, Nebert DW.
    Biochem Biophys Res Commun; 2000 Dec 20; 279(2):324-9. PubMed ID: 11118286
    [Abstract] [Full Text] [Related]

  • 17. Activation of promoter activity of the catalytic subunit of γ-glutamylcysteine ligase (GCL) in brain endothelial cells by insulin requires antioxidant response element 4 and altered glycemic status: implication for GCL expression and GSH synthesis.
    Langston JW, Li W, Harrison L, Aw TY.
    Free Radic Biol Med; 2011 Nov 01; 51(9):1749-57. PubMed ID: 21871559
    [Abstract] [Full Text] [Related]

  • 18. Targeting of Gamma-Glutamyl-Cysteine Ligase by miR-433 Reduces Glutathione Biosynthesis and Promotes TGF-β-Dependent Fibrogenesis.
    Espinosa-Diez C, Fierro-Fernández M, Sánchez-Gómez F, Rodríguez-Pascual F, Alique M, Ruiz-Ortega M, Beraza N, Martínez-Chantar ML, Fernández-Hernando C, Lamas S.
    Antioxid Redox Signal; 2015 Nov 10; 23(14):1092-105. PubMed ID: 25353619
    [Abstract] [Full Text] [Related]

  • 19. Phloroglucinol (1,3,5-trihydroxybenzene) protects against ionizing radiation-induced cell damage through inhibition of oxidative stress in vitro and in vivo.
    Kang KA, Zhang R, Chae S, Lee SJ, Kim J, Kim J, Jeong J, Lee J, Shin T, Lee NH, Hyun JW.
    Chem Biol Interact; 2010 May 14; 185(3):215-26. PubMed ID: 20188716
    [Abstract] [Full Text] [Related]

  • 20. Cytochrome P450 2E1 responsiveness in the promoter of glutamate-cysteine ligase catalytic subunit.
    Nieto N, Marí M, Cederbaum AI.
    Hepatology; 2003 Jan 14; 37(1):96-106. PubMed ID: 12500194
    [Abstract] [Full Text] [Related]

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