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Journal Abstract Search

529 related items for PubMed ID: 19157881

  • 1. Synthesis and cyclooxygenase inhibition of various (aryl-1,2,3-triazole-1-yl)-methanesulfonylphenyl derivatives.
    Wuest F, Tang X, Kniess T, Pietzsch J, Suresh M.
    Bioorg Med Chem; 2009 Feb 01; 17(3):1146-51. PubMed ID: 19157881
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  • 2. Synthesis and structure-activity relationship of novel, highly potent metharyl and methcycloalkyl cyclooxygenase-2 (COX-2) selective inhibitors.
    Khanapure SP, Garvey DS, Young DV, Ezawa M, Earl RA, Gaston RD, Fang X, Murty M, Martino A, Shumway M, Trocha M, Marek P, Tam SW, Janero DR, Letts LG.
    J Med Chem; 2003 Dec 04; 46(25):5484-504. PubMed ID: 14640557
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  • 7. Design, synthesis, and biological evaluation of (E)-3-(4-methanesulfonylphenyl)-2-(aryl)acrylic acids as dual inhibitors of cyclooxygenases and lipoxygenases.
    Moreau A, Chen QH, Praveen Rao PN, Knaus EE.
    Bioorg Med Chem; 2006 Dec 01; 14(23):7716-27. PubMed ID: 16931030
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  • 8. Design, synthesis, and structure-activity relationship studies of 3,4,6-triphenylpyran-2-ones as selective cyclooxygenase-2 inhibitors.
    Rao PN, Uddin MJ, Knaus EE.
    J Med Chem; 2004 Jul 29; 47(16):3972-90. PubMed ID: 15267236
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  • 10. Synthesis and biological evaluation of linear phenylethynylbenzenesulfonamide regioisomers as cyclooxygenase-1/-2 (COX-1/-2) inhibitors.
    Anana R, Rao PN, Chen QH, Knaus EE.
    Bioorg Med Chem; 2006 Aug 01; 14(15):5259-65. PubMed ID: 16635574
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  • 11. Design, synthesis, and biological evaluation of N-acetyl-2-(or 3-)carboxymethylbenzenesulfonamides as cyclooxygenase isozyme inhibitors.
    Chen QH, Rao PN, Knaus EE.
    Bioorg Med Chem; 2005 Aug 01; 13(15):4694-703. PubMed ID: 15914011
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  • 12. Design and synthesis of 1,3-diarylurea derivatives as selective cyclooxygenase (COX-2) inhibitors.
    Zarghi A, Kakhgi S, Hadipoor A, Daraee B, Dadrass OG, Hedayati M.
    Bioorg Med Chem Lett; 2008 Feb 15; 18(4):1336-9. PubMed ID: 18226898
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  • 13. Design and synthesis of new rofecoxib analogs as selective cyclooxygenase-2 (COX-2) inhibitors: replacement of the methanesulfonyl pharmacophore by a N-acetylsulfonamido bioisostere.
    Zarghi A, Rao PN, Knaus EE.
    J Pharm Pharm Sci; 2007 Feb 15; 10(2):159-67. PubMed ID: 17706175
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  • 14. Design, synthesis, and biological evaluation of linear 1-(4-, 3- or 2-methylsulfonylphenyl)-2-phenylacetylenes: a novel class of cyclooxygenase-2 inhibitors.
    Chen QH, Rao PN, Knaus EE.
    Bioorg Med Chem; 2005 Dec 01; 13(23):6425-34. PubMed ID: 16099663
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  • 15. 1,4-Diaryl-substituted triazoles as cyclooxygenase-2 inhibitors: Synthesis, biological evaluation and molecular modeling studies.
    Kaur J, Bhardwaj A, Sharma SK, Wuest F.
    Bioorg Med Chem; 2013 Jul 15; 21(14):4288-95. PubMed ID: 23706267
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  • 16. Structure-activity studies on a 1,2,3-triazole derivative, a potent in vitro inhibitor of prostaglandin synthesis: the role of the heterocyclic ring.
    Biagi G, Dell'Omodarme G, Ferretti M, Giorgi I, Livi O, Scartoni V.
    Farmaco; 1992 Mar 15; 47(3):335-44. PubMed ID: 1503597
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  • 17. Comparative structure-activity relationship studies of 1-(5-methylsulfonylpyrid-2-yl)-5-alkyl and (hetero)aryl triazoles and pyrazoles in canine COX inhibition.
    Sakya SM, Shavnya A, Cheng H, Li C, Rast B, Li J, Koss DA, Jaynes BH, Mann DW, Petras CF, Seibel SB, Haven ML, Lynch MP.
    Bioorg Med Chem Lett; 2008 Feb 01; 18(3):1042-5. PubMed ID: 18182290
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  • 18. Design, synthesis, and biological evaluation of N-acetyl-2-carboxybenzenesulfonamides: a novel class of cyclooxygenase-2 (COX-2) inhibitors.
    Chen QH, Rao PN, Knaus EE.
    Bioorg Med Chem; 2005 Apr 01; 13(7):2459-68. PubMed ID: 15755648
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  • 19. Synthesis and biological evaluation of a novel class of rofecoxib analogues as dual inhibitors of cyclooxygenases (COXs) and lipoxygenases (LOXs).
    Chen QH, Rao PN, Knaus EE.
    Bioorg Med Chem; 2006 Dec 01; 14(23):7898-909. PubMed ID: 16904331
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  • 20. General role of the amino and methylsulfamoyl groups in selective cyclooxygenase(COX)-1 inhibition by 1,4-diaryl-1,2,3-triazoles and validation of a predictive pharmacometric PLS model.
    Perrone MG, Vitale P, Panella A, Fortuna CG, Scilimati A.
    Eur J Med Chem; 2015 Apr 13; 94():252-64. PubMed ID: 25768707
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