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430 related items for PubMed ID: 19176369

  • 1. Inhibition of class I phosphoinositide 3-kinase activity impairs proliferation and triggers apoptosis in acute promyelocytic leukemia without affecting atra-induced differentiation.
    Billottet C, Banerjee L, Vanhaesebroeck B, Khwaja A.
    Cancer Res; 2009 Feb 01; 69(3):1027-36. PubMed ID: 19176369
    [Abstract] [Full Text] [Related]

  • 2. Programmed cell death-4 tumor suppressor protein contributes to retinoic acid-induced terminal granulocytic differentiation of human myeloid leukemia cells.
    Ozpolat B, Akar U, Steiner M, Zorrilla-Calancha I, Tirado-Gomez M, Colburn N, Danilenko M, Kornblau S, Berestein GL.
    Mol Cancer Res; 2007 Jan 01; 5(1):95-108. PubMed ID: 17259349
    [Abstract] [Full Text] [Related]

  • 3. Antimyeloma activity of the orally bioavailable dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235.
    McMillin DW, Ooi M, Delmore J, Negri J, Hayden P, Mitsiades N, Jakubikova J, Maira SM, Garcia-Echeverria C, Schlossman R, Munshi NC, Richardson PG, Anderson KC, Mitsiades CS.
    Cancer Res; 2009 Jul 15; 69(14):5835-42. PubMed ID: 19584292
    [Abstract] [Full Text] [Related]

  • 4. Targeting the phosphoinositide 3-kinase isoform p110delta impairs growth and survival in neuroblastoma cells.
    Boller D, Schramm A, Doepfner KT, Shalaby T, von Bueren AO, Eggert A, Grotzer MA, Arcaro A.
    Clin Cancer Res; 2008 Feb 15; 14(4):1172-81. PubMed ID: 18281552
    [Abstract] [Full Text] [Related]

  • 5. Targeting the PI3K p110alpha isoform inhibits medulloblastoma proliferation, chemoresistance, and migration.
    Guerreiro AS, Fattet S, Fischer B, Shalaby T, Jackson SP, Schoenwaelder SM, Grotzer MA, Delattre O, Arcaro A.
    Clin Cancer Res; 2008 Nov 01; 14(21):6761-9. PubMed ID: 18980969
    [Abstract] [Full Text] [Related]

  • 6. Survival signaling by Notch1: mammalian target of rapamycin (mTOR)-dependent inhibition of p53.
    Mungamuri SK, Yang X, Thor AD, Somasundaram K.
    Cancer Res; 2006 May 01; 66(9):4715-24. PubMed ID: 16651424
    [Abstract] [Full Text] [Related]

  • 7. The Akt/mammalian target of rapamycin signal transduction pathway is activated in high-risk myelodysplastic syndromes and influences cell survival and proliferation.
    Follo MY, Mongiorgi S, Bosi C, Cappellini A, Finelli C, Chiarini F, Papa V, Libra M, Martinelli G, Cocco L, Martelli AM.
    Cancer Res; 2007 May 01; 67(9):4287-94. PubMed ID: 17483341
    [Abstract] [Full Text] [Related]

  • 8. Mutations in the catalytic subunit of class IA PI3K confer leukemogenic potential to hematopoietic cells.
    Horn S, Bergholz U, Jücker M, McCubrey JA, Trümper L, Stocking C, Bäsecke J.
    Oncogene; 2008 Jul 03; 27(29):4096-106. PubMed ID: 18317450
    [Abstract] [Full Text] [Related]

  • 9. Phosphatidylinositol 3-kinase inhibition broadly sensitizes glioblastoma cells to death receptor- and drug-induced apoptosis.
    Opel D, Westhoff MA, Bender A, Braun V, Debatin KM, Fulda S.
    Cancer Res; 2008 Aug 01; 68(15):6271-80. PubMed ID: 18676851
    [Abstract] [Full Text] [Related]

  • 10. Sorafenib Inhibition of Mcl-1 Accelerates ATRA-Induced Apoptosis in Differentiation-Responsive AML Cells.
    Wang R, Xia L, Gabrilove J, Waxman S, Jing Y.
    Clin Cancer Res; 2016 Mar 01; 22(5):1211-21. PubMed ID: 26459180
    [Abstract] [Full Text] [Related]

  • 11. Death-associated protein 5 (DAP5/p97/NAT1) contributes to retinoic acid-induced granulocytic differentiation and arsenic trioxide-induced apoptosis in acute promyelocytic leukemia.
    Ozpolat B, Akar U, Zorrilla-Calancha I, Vivas-Mejia P, Acevedo-Alvarez M, Lopez-Berestein G.
    Apoptosis; 2008 Jul 01; 13(7):915-28. PubMed ID: 18491231
    [Abstract] [Full Text] [Related]

  • 12. Induction of differentiation of acute promyelocytic leukemia cells by a cytidine deaminase-resistant analogue of 1-beta-D-arabinofuranosylcytosine, 1-(2-deoxy-2-methylene-beta-D-erythro-pentofuranosyl)cytidine.
    Niitsu N, Ishii Y, Matsuda A, Honma Y.
    Cancer Res; 2001 Jan 01; 61(1):178-85. PubMed ID: 11196157
    [Abstract] [Full Text] [Related]

  • 13. Apoptosis induction by (+)alpha-tocopheryl succinate in the absence or presence of all-trans retinoic acid and arsenic trioxide in NB4, NB4-R2 and primary APL cells.
    Freitas RA, Silva dos Santos GA, Gimenes Teixeira HL, Scheucher PS, Lucena-Araujo AR, Lima AS, Abreu e Lima RS, Garcia AB, Jordão AA, Falcão RP, Vannucchi H, Rego EM.
    Leuk Res; 2009 Jul 01; 33(7):958-63. PubMed ID: 19013639
    [Abstract] [Full Text] [Related]

  • 14. Granulocyte colony-stimulating factor potentiates differentiation induction by all-trans retinoic acid and arsenic trioxide and enhances arsenic uptake in the acute promyelocytic leukemia cell line HT93A.
    Iriyama N, Yuan B, Hatta Y, Horikoshi A, Yoshino Y, Toyoda H, Aizawa S, Takeuchi J.
    Oncol Rep; 2012 Nov 01; 28(5):1875-82. PubMed ID: 22940758
    [Abstract] [Full Text] [Related]

  • 15. Handicapping the race to develop inhibitors of the phosphoinositide 3-kinase/Akt/mammalian target of rapamycin pathway.
    Granville CA, Memmott RM, Gills JJ, Dennis PA.
    Clin Cancer Res; 2006 Feb 01; 12(3 Pt 1):679-89. PubMed ID: 16467077
    [Abstract] [Full Text] [Related]

  • 16. Upregulation of nitric oxide production in vascular endothelial cells by all-trans retinoic acid through the phosphoinositide 3-kinase/Akt pathway.
    Uruno A, Sugawara A, Kanatsuka H, Kagechika H, Saito A, Sato K, Kudo M, Takeuchi K, Ito S.
    Circulation; 2005 Aug 02; 112(5):727-36. PubMed ID: 16043647
    [Abstract] [Full Text] [Related]

  • 17. Retinoid-induced activation of NF-kappaB in APL cells is not essential for granulocytic differentiation, but prolongs the life span of mature cells.
    Mathieu J, Giraudier S, Lanotte M, Besançon F.
    Oncogene; 2005 Nov 03; 24(48):7145-55. PubMed ID: 16044154
    [Abstract] [Full Text] [Related]

  • 18. Both p110alpha and p110beta isoforms of phosphatidylinositol 3-OH-kinase are required for insulin signalling in the hypothalamus.
    Tups A, Anderson GM, Rizwan M, Augustine RA, Chaussade C, Shepherd PR, Grattan DR.
    J Neuroendocrinol; 2010 Jun 03; 22(6):534-42. PubMed ID: 20236230
    [Abstract] [Full Text] [Related]

  • 19. ATRA can enhance apoptosis that is induced by Flt3 tyrosine kinase inhibition in Flt3-ITD positive cells.
    Scholl S, Müller R, Clement JH, Loncarevic IF, Böhmer FD, Höffken K.
    Leuk Res; 2006 May 03; 30(5):633-42. PubMed ID: 16473406
    [Abstract] [Full Text] [Related]

  • 20. Phosphoinositide 3-kinase/Akt inhibition increases arsenic trioxide-induced apoptosis of acute promyelocytic and T-cell leukaemias.
    Tabellini G, Tazzari PL, Bortul R, Evangelisti C, Billi AM, Grafone T, Martinelli G, Baccarani M, Martelli AM.
    Br J Haematol; 2005 Sep 03; 130(5):716-25. PubMed ID: 16115127
    [Abstract] [Full Text] [Related]

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