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Journal Abstract Search


340 related items for PubMed ID: 19176456

  • 1. T670X KIT mutations in gastrointestinal stromal tumors: making sense of missense.
    Negri T, Pavan GM, Virdis E, Greco A, Fermeglia M, Sandri M, Pricl S, Pierotti MA, Pilotti S, Tamborini E.
    J Natl Cancer Inst; 2009 Feb 04; 101(3):194-204. PubMed ID: 19176456
    [Abstract] [Full Text] [Related]

  • 2. Pathologic and molecular heterogeneity in imatinib-stable or imatinib-responsive gastrointestinal stromal tumors.
    Agaram NP, Besmer P, Wong GC, Guo T, Socci ND, Maki RG, DeSantis D, Brennan MF, Singer S, DeMatteo RP, Antonescu CR.
    Clin Cancer Res; 2007 Jan 01; 13(1):170-81. PubMed ID: 17200352
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  • 4. Analysis of KIT mutations in sporadic and familial gastrointestinal stromal tumors: therapeutic implications through protein modeling.
    Tarn C, Merkel E, Canutescu AA, Shen W, Skorobogatko Y, Heslin MJ, Eisenberg B, Birbe R, Patchefsky A, Dunbrack R, Arnoletti JP, von Mehren M, Godwin AK.
    Clin Cancer Res; 2005 May 15; 11(10):3668-77. PubMed ID: 15897563
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  • 5. KIT oncogenic signaling mechanisms in imatinib-resistant gastrointestinal stromal tumor: PI3-kinase/AKT is a crucial survival pathway.
    Bauer S, Duensing A, Demetri GD, Fletcher JA.
    Oncogene; 2007 Nov 29; 26(54):7560-8. PubMed ID: 17546049
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  • 6. Effects of imatinib vary with the types of KIT-mutation in gastrointestinal stromal tumor cell lines.
    Noma K, Naomoto Y, Gunduz M, Matsuoka J, Yamatsuji T, Shirakawa Y, Nobuhisa T, Okawa T, Takaoka M, Tomono Y, Hiroyuki O, Gunduz E, Tanaka N.
    Oncol Rep; 2005 Sep 29; 14(3):645-50. PubMed ID: 16077968
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  • 7. Secondary C-kit mutation is a cause of acquired resistance to imatinib in gastrointestinal stromal tumor.
    Zheng S, Pan YL, Tao DY, Wang JL, Huang KE.
    Scand J Gastroenterol; 2009 Sep 29; 44(6):760-3. PubMed ID: 19096980
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  • 8. c-Kit/PDGFRA gene status alterations possibly related to primary imatinib resistance in gastrointestinal stromal tumors.
    Miselli FC, Casieri P, Negri T, Orsenigo M, Lagonigro MS, Gronchi A, Fiore M, Casali PG, Bertulli R, Carbone A, Pierotti MA, Tamborini E, Pilotti S.
    Clin Cancer Res; 2007 Apr 15; 13(8):2369-77. PubMed ID: 17438095
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  • 11. [Activating mutations in receptor tyrosine kinases with relevance for treatment of gastrointestinal stromal tumors].
    Wardelmann E, Merkelbach-Bruse S, Büttner R, Schildhaus HU.
    Verh Dtsch Ges Pathol; 2007 Apr 15; 91():165-8. PubMed ID: 18314611
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  • 12. KIT/Val654 Ala receptor detected in one imatinib-resistant GIST patient.
    Tamborini E, Gabanti E, Lagonigro MS, Negri T, Pilotti S, Pierotti MA, Pricl S.
    Cancer Res; 2005 Feb 01; 65(3):1115; author reply 1115. PubMed ID: 15705916
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  • 13. C6-unsubstituted pyrazolo[3,4-d]pyrimidines are dual Src/Abl inhibitors effective against imatinib mesylate resistant chronic myeloid leukemia cell lines.
    Santucci MA, Corradi V, Mancini M, Manetti F, Radi M, Schenone S, Botta M.
    ChemMedChem; 2009 Jan 01; 4(1):118-26. PubMed ID: 19039816
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  • 14. [Small-molecule inhibitors against KIT and PDGFRs especially in GISTs].
    Shiba K, Matsumoto T, Hirota S.
    Gan To Kagaku Ryoho; 2009 Jul 01; 36(7):1080-5. PubMed ID: 19620796
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  • 16. Acquired resistance to imatinib and secondary KIT exon 13 mutation in gastrointestinal stromal tumour.
    Bertucci F, Goncalves A, Monges G, Madroszyk A, Guiramand J, Moutardier V, Noguchi T, Dubreuil P, Sobol H.
    Oncol Rep; 2006 Jul 01; 16(1):97-101. PubMed ID: 16786129
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  • 17. Surgical management after neoadjuvant imatinib therapy in gastrointestinal stromal tumours (GISTs) with respect to imatinib resistance caused by secondary KIT mutations.
    Haller F, Detken S, Schulten HJ, Happel N, Gunawan B, Kuhlgatz J, Füzesi L.
    Ann Surg Oncol; 2007 Feb 01; 14(2):526-32. PubMed ID: 17139461
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  • 18. KIT oncoprotein interactions in gastrointestinal stromal tumors: therapeutic relevance.
    Zhu MJ, Ou WB, Fletcher CD, Cohen PS, Demetri GD, Fletcher JA.
    Oncogene; 2007 Sep 27; 26(44):6386-95. PubMed ID: 17452978
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