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101 related items for PubMed ID: 19203270

  • 1. Synthesis, biological evaluation, and docking studies of N-substituted acetamidines as selective inhibitors of inducible nitric oxide synthase.
    Maccallini C, Patruno A, Besker N, Alì JI, Ammazzalorso A, De Filippis B, Franceschelli S, Giampietro L, Pesce M, Reale M, Tricca ML, Re N, Felaco M, Amoroso R.
    J Med Chem; 2009 Mar 12; 52(5):1481-5. PubMed ID: 19203270
    [Abstract] [Full Text] [Related]

  • 2. N-Phenylamidines as selective inhibitors of human neuronal nitric oxide synthase: structure-activity studies and demonstration of in vivo activity.
    Collins JL, Shearer BG, Oplinger JA, Lee S, Garvey EP, Salter M, Duffy C, Burnette TC, Furfine ES.
    J Med Chem; 1998 Jul 16; 41(15):2858-71. PubMed ID: 9667974
    [Abstract] [Full Text] [Related]

  • 3. Differential effects of selective and non-selective inhibition of nitric oxide synthase on the expression and activity of cyclooxygenase-2 during gastric ulcer healing.
    Guo JS, Cho CH, Wang JY, Koo MW.
    Eur J Pharmacol; 2006 May 01; 536(3):301-8. PubMed ID: 16600210
    [Abstract] [Full Text] [Related]

  • 4. Suppression of acute experimental colitis by a highly selective inducible nitric-oxide synthase inhibitor, N-[3-(aminomethyl)benzyl]acetamidine.
    Kankuri E, Vaali K, Knowles RG, Lähde M, Korpela R, Vapaatalo H, Moilanen E.
    J Pharmacol Exp Ther; 2001 Sep 01; 298(3):1128-32. PubMed ID: 11504810
    [Abstract] [Full Text] [Related]

  • 5. N-Substituted acetamidines and 2-methylimidazole derivatives as selective inhibitors of neuronal nitric oxide synthase.
    Maccallini C, Patruno A, Lannutti F, Ammazzalorso A, De Filippis B, Fantacuzzi M, Franceschelli S, Giampietro L, Masella S, Felaco M, Re N, Amoroso R.
    Bioorg Med Chem Lett; 2010 Nov 15; 20(22):6495-9. PubMed ID: 20933416
    [Abstract] [Full Text] [Related]

  • 6. Selective inhibition of iNOS by benzyl- and dibenzyl derivatives of N-(3-aminobenzyl)acetamidine.
    Fantacuzzi M, Maccallini C, Lannutti F, Patruno A, Masella S, Pesce M, Speranza L, Ammazzalorso A, De Filippis B, Giampietro L, Re N, Amoroso R.
    ChemMedChem; 2011 Jul 04; 6(7):1203-6. PubMed ID: 21567968
    [No Abstract] [Full Text] [Related]

  • 7. Phenylpyrrole derivatives as neural and inducible nitric oxide synthase (nNOS and iNOS) inhibitors.
    López Cara LC, Camacho ME, Carrión MD, Tapias V, Gallo MA, Escames G, Acuña-Castroviejo D, Espinosa A, Entrena A.
    Eur J Med Chem; 2009 Jun 04; 44(6):2655-66. PubMed ID: 19117642
    [Abstract] [Full Text] [Related]

  • 8. Heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase; the identification of (2R)-2-pyrrolidinecarboxamidine as a potent and selective haem-co-ordinating inhibitor.
    Young RJ, Alderton W, Angell AD, Beswick PJ, Brown D, Chambers CL, Crowe MC, Dawson J, Hamlett CC, Hodgson ST, Kleanthous S, Knowles RG, Russell LJ, Stocker R, Woolven JM.
    Bioorg Med Chem Lett; 2011 May 15; 21(10):3037-40. PubMed ID: 21482467
    [Abstract] [Full Text] [Related]

  • 9. Discovery of a series of aminopiperidines as novel iNOS inhibitors.
    Le Bourdonnec B, Leister LK, Ajello CA, Cassel JA, Seida PR, O'Hare H, Gu M, Chu GH, Tuthill PA, DeHaven RN, Dolle RE.
    Bioorg Med Chem Lett; 2008 Jan 01; 18(1):336-43. PubMed ID: 18024030
    [Abstract] [Full Text] [Related]

  • 10. Aromatic reduced amide bond peptidomimetics as selective inhibitors of neuronal nitric oxide synthase.
    Hah JM, Martásek P, Roman LJ, Silverman RB.
    J Med Chem; 2003 Apr 24; 46(9):1661-9. PubMed ID: 12699384
    [Abstract] [Full Text] [Related]

  • 11. Pyrazoles and pyrazolines as neural and inducible nitric oxide synthase (nNOS and iNOS) potential inhibitors (III).
    Carrión MD, López Cara LC, Camacho ME, Tapias V, Escames G, Acuña-Castroviejo D, Espinosa A, Gallo MA, Entrena A.
    Eur J Med Chem; 2008 Nov 24; 43(11):2579-91. PubMed ID: 18325637
    [Abstract] [Full Text] [Related]

  • 12. Hindlimb ischemia/reperfusion-induced remote injury to the small intestine: role of inducible nitric-oxide synthase-derived nitric oxide.
    Katada K, Bihari A, Badhwar A, Yoshida N, Yoshikawa T, Potter RF, Cepinskas G.
    J Pharmacol Exp Ther; 2009 Jun 24; 329(3):919-27. PubMed ID: 19270191
    [Abstract] [Full Text] [Related]

  • 13. The novel imidazopyridine 2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine (BYK191023) is a highly selective inhibitor of the inducible nitric-oxide synthase.
    Strub A, Ulrich WR, Hesslinger C, Eltze M, Fuchss T, Strassner J, Strand S, Lehner MD, Boer R.
    Mol Pharmacol; 2006 Jan 24; 69(1):328-37. PubMed ID: 16223957
    [Abstract] [Full Text] [Related]

  • 14. Discovery of N-{3-[(ethanimidoylamino)methyl]benzyl}-l-prolinamide dihydrochloride: A new potent and selective inhibitor of the inducible nitric oxide synthase as a promising agent for the therapy of malignant glioma.
    Maccallini C, Di Matteo M, Gallorini M, Montagnani M, Graziani V, Ammazzalorso A, Amoia P, De Filippis B, Di Silvestre S, Fantacuzzi M, Giampietro L, Potenza MA, Re N, Pandolfi A, Cataldi A, Amoroso R.
    Eur J Med Chem; 2018 May 25; 152():53-64. PubMed ID: 29689474
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of inducible nitric oxide synthase and superoxide production reduces matrix metalloproteinase-9 activity and restores coronary vasomotor function in rat cardiac allografts.
    Egi K, Conrad NE, Kwan J, Schulze C, Schulz R, Wildhirt SM.
    Eur J Cardiothorac Surg; 2004 Aug 25; 26(2):262-9. PubMed ID: 15296881
    [Abstract] [Full Text] [Related]

  • 16. Screening of NOS activity and selectivity of newly synthesized acetamidines using RP-HPLC.
    Fantacuzzi M, Maccallini C, Di Matteo M, Ammazzalorso A, Bruno I, De Filippis B, Giampietro L, Mollica A, Amoroso R.
    J Pharm Biomed Anal; 2016 Feb 20; 120():419-24. PubMed ID: 26689740
    [Abstract] [Full Text] [Related]

  • 17. Selective inhibition of inducible nitric oxide synthase reduces neurological deficit but not cerebral edema following traumatic brain injury.
    Louin G, Marchand-Verrecchia C, Palmier B, Plotkine M, Jafarian-Tehrani M.
    Neuropharmacology; 2006 Feb 20; 50(2):182-90. PubMed ID: 16242164
    [Abstract] [Full Text] [Related]

  • 18. Structure-activity relationship of novel and known inhibitors of human dimethylarginine dimethylaminohydrolase-1: alkenyl-amidines as new leads.
    Kotthaus J, Schade D, Muschick N, Beitz E, Clement B.
    Bioorg Med Chem; 2008 Dec 15; 16(24):10205-9. PubMed ID: 19013076
    [Abstract] [Full Text] [Related]

  • 19. Differential binding of calmodulin domains to constitutive and inducible nitric oxide synthase enzymes.
    Spratt DE, Taiakina V, Palmer M, Guillemette JG.
    Biochemistry; 2007 Jul 17; 46(28):8288-300. PubMed ID: 17580957
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and evaluation of new sulfur-containing L-arginine-derived inhibitors of nitric oxide synthase.
    Ichimori K, Stuehr DJ, Atkinson RN, King SB.
    J Med Chem; 1999 May 20; 42(10):1842-8. PubMed ID: 10346937
    [Abstract] [Full Text] [Related]

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