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193 related items for PubMed ID: 19204737

  • 1. Influence of the G2677T/C3435T haplotype of MDR1 on P-glycoprotein trafficking and ibutilide-induced block of HERG.
    McBride BF, Yang T, Roden DM.
    Pharmacogenomics J; 2009 Jun; 9(3):194-201. PubMed ID: 19204737
    [Abstract] [Full Text] [Related]

  • 2. The drug-transporter gene MDR1 C3435T and G2677T/A polymorphisms and the risk of multidrug-resistant epilepsy in Turkish children.
    Seven M, Batar B, Unal S, Yesil G, Yuksel A, Guven M.
    Mol Biol Rep; 2014 Jan; 41(1):331-6. PubMed ID: 24213830
    [Abstract] [Full Text] [Related]

  • 3. Modulation of drug block of the cardiac potassium channel KCNA5 by the drug transporters OCTN1 and MDR1.
    Yang T, McBride BF, Leake BF, Kim RB, Roden DM.
    Br J Pharmacol; 2010 Nov; 161(5):1023-33. PubMed ID: 20977453
    [Abstract] [Full Text] [Related]

  • 4. Extracellular acidification and hyperkalemia induce changes in HERG inhibition by ibutilide.
    Lin C, Ke X, Ranade V, Somberg J.
    Cardiology; 2008 Nov; 110(3):209-16. PubMed ID: 18057887
    [Abstract] [Full Text] [Related]

  • 5. Impact of MDR1 haplotypes derived from C1236T, G2677T/A and C3435T on the pharmacokinetics of single-dose oral digoxin in healthy Chinese volunteers.
    Xu P, Jiang ZP, Zhang BK, Tu JY, Li HD.
    Pharmacology; 2008 Nov; 82(3):221-7. PubMed ID: 18810246
    [Abstract] [Full Text] [Related]

  • 6. The organic cation transporter, OCTN1, expressed in the human heart, potentiates antagonism of the HERG potassium channel.
    McBride BF, Yang T, Liu K, Urban TJ, Giacomini KM, Kim RB, Roden DM.
    J Cardiovasc Pharmacol; 2009 Jul; 54(1):63-71. PubMed ID: 19528813
    [Abstract] [Full Text] [Related]

  • 7. High baseline serum total and LDL cholesterol levels are associated with MDR1 haplotypes in Brazilian hypercholesterolemic individuals of European descent.
    Rodrigues AC, Rebecchi IM, Bertolami MC, Faludi AA, Hirata MH, Hirata RD.
    Braz J Med Biol Res; 2005 Sep; 38(9):1389-97. PubMed ID: 16138223
    [Abstract] [Full Text] [Related]

  • 8. Frequency of G2677T/A and C3435T polymorphisms of MDR1 gene in preeclamptic women.
    Bogacz A, Mrozikiewicz PM, Deka-Pawlik D, Seremak-Mrozikiewicz A, Bartkowiak-Wieczorek J, Barlik M, Drews K, Kowalska A, Grześkowiak E.
    Ginekol Pol; 2013 Sep; 84(9):781-7. PubMed ID: 24191517
    [Abstract] [Full Text] [Related]

  • 9. Structural determinants of HERG channel block by clofilium and ibutilide.
    Perry M, de Groot MJ, Helliwell R, Leishman D, Tristani-Firouzi M, Sanguinetti MC, Mitcheson J.
    Mol Pharmacol; 2004 Aug; 66(2):240-9. PubMed ID: 15266014
    [Abstract] [Full Text] [Related]

  • 10. Correlation between MDR1 methylation status in the promoter region and MDR1 genetic polymorphism in 194 healthy Chinese Han subjects.
    Jiang ZP, Xu P, Liu RR, Li HD, Wang GP, Zhao XL, Chen FP.
    Pharmacogenomics; 2008 Dec; 9(12):1801-8. PubMed ID: 19072639
    [Abstract] [Full Text] [Related]

  • 11. Drug binding interactions in the inner cavity of HERG channels: molecular insights from structure-activity relationships of clofilium and ibutilide analogs.
    Perry M, Stansfeld PJ, Leaney J, Wood C, de Groot MJ, Leishman D, Sutcliffe MJ, Mitcheson JS.
    Mol Pharmacol; 2006 Feb; 69(2):509-19. PubMed ID: 16291873
    [Abstract] [Full Text] [Related]

  • 12. Drug block of I(kr): model systems and relevance to human arrhythmias.
    Yang T, Snyders D, Roden DM.
    J Cardiovasc Pharmacol; 2001 Nov; 38(5):737-44. PubMed ID: 11602820
    [Abstract] [Full Text] [Related]

  • 13. [Relationship between genetic polymorphism of multidrug resistance 1 gene and the risk of childhood acute lymphocytic leukemia].
    Lü H, Du ZZ, Wang W, Wang W, Zhao WL, Wang Y, Hu SY, Chai YH.
    Zhonghua Er Ke Za Zhi; 2012 Sep; 50(9):692-6. PubMed ID: 23158821
    [Abstract] [Full Text] [Related]

  • 14. MDR1 genotypes do not influence the absorption of a single oral dose of 600 mg valacyclovir in healthy Chinese Han ethnic males.
    Zhang Y, Jiang XH, Hu YQ, Li ZR, Su L, Wang ZG, Ma G.
    Br J Clin Pharmacol; 2008 Aug; 66(2):247-54. PubMed ID: 18460034
    [Abstract] [Full Text] [Related]

  • 15. Modulation of human placental P-glycoprotein expression and activity by MDR1 gene polymorphisms.
    Hemauer SJ, Nanovskaya TN, Abdel-Rahman SZ, Patrikeeva SL, Hankins GD, Ahmed MS.
    Biochem Pharmacol; 2010 Mar 15; 79(6):921-5. PubMed ID: 19896927
    [Abstract] [Full Text] [Related]

  • 16. MDR1 polymorphisms G2677T in exon 21 and C3435T in exon 26 fail to affect rhodamine 123 efflux in peripheral blood lymphocytes.
    Oselin K, Gerloff T, Mrozikiewicz PM, Pähkla R, Roots I.
    Fundam Clin Pharmacol; 2003 Aug 15; 17(4):463-9. PubMed ID: 12914549
    [Abstract] [Full Text] [Related]

  • 17. Variable expression of P-glycoprotein in the human placenta and its association with mutations of the multidrug resistance 1 gene (MDR1, ABCB1).
    Hitzl M, Schaeffeler E, Hocher B, Slowinski T, Halle H, Eichelbaum M, Kaufmann P, Fritz P, Fromm MF, Schwab M.
    Pharmacogenetics; 2004 May 15; 14(5):309-18. PubMed ID: 15115917
    [Abstract] [Full Text] [Related]

  • 18. Frequency of the C1236T, G2677T/A and C3435T MDR1 gene polymorphisms in the Serbian population.
    Milojkovic M, Stojnev S, Jovanovic I, Ljubisavljevic S, Stefanovic V, Sunder-Plassman R.
    Pharmacol Rep; 2011 May 15; 63(3):808-14. PubMed ID: 21857092
    [Abstract] [Full Text] [Related]

  • 19. The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutations.
    Ficker E, Obejero-Paz CA, Zhao S, Brown AM.
    J Biol Chem; 2002 Feb 15; 277(7):4989-98. PubMed ID: 11741928
    [Abstract] [Full Text] [Related]

  • 20. MDR1 synonymous polymorphisms alter transporter specificity and protein stability in a stable epithelial monolayer.
    Fung KL, Pan J, Ohnuma S, Lund PE, Pixley JN, Kimchi-Sarfaty C, Ambudkar SV, Gottesman MM.
    Cancer Res; 2014 Jan 15; 74(2):598-608. PubMed ID: 24305879
    [Abstract] [Full Text] [Related]

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