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160 related items for PubMed ID: 19211691

  • 1. Charge-to-substrate ratio during organic cation uptake by rat OCT2 is voltage dependent and altered by exchange of glutamate 448 with glutamine.
    Schmitt BM, Gorbunov D, Schlachtbauer P, Egenberger B, Gorboulev V, Wischmeyer E, Müller T, Koepsell H.
    Am J Physiol Renal Physiol; 2009 Apr; 296(4):F709-22. PubMed ID: 19211691
    [Abstract] [Full Text] [Related]

  • 2. Five amino acids in the innermost cavity of the substrate binding cleft of organic cation transporter 1 interact with extracellular and intracellular corticosterone.
    Volk C, Gorboulev V, Kotzsch A, Müller TD, Koepsell H.
    Mol Pharmacol; 2009 Aug; 76(2):275-89. PubMed ID: 19435783
    [Abstract] [Full Text] [Related]

  • 3. Different affinities of inhibitors to the outwardly and inwardly directed substrate binding site of organic cation transporter 2.
    Volk C, Gorboulev V, Budiman T, Nagel G, Koepsell H.
    Mol Pharmacol; 2003 Nov; 64(5):1037-47. PubMed ID: 14573752
    [Abstract] [Full Text] [Related]

  • 4. Subtype-specific affinity for corticosterone of rat organic cation transporters rOCT1 and rOCT2 depends on three amino acids within the substrate binding region.
    Gorboulev V, Shatskaya N, Volk C, Koepsell H.
    Mol Pharmacol; 2005 May; 67(5):1612-9. PubMed ID: 15662045
    [Abstract] [Full Text] [Related]

  • 5. Identification of cysteines in rat organic cation transporters rOCT1 (C322, C451) and rOCT2 (C451) critical for transport activity and substrate affinity.
    Sturm A, Gorboulev V, Gorbunov D, Keller T, Volk C, Schmitt BM, Schlachtbauer P, Ciarimboli G, Koepsell H.
    Am J Physiol Renal Physiol; 2007 Sep; 293(3):F767-79. PubMed ID: 17567940
    [Abstract] [Full Text] [Related]

  • 6. Alkali cation binding and permeation in the rat organic cation transporter rOCT2.
    Schmitt BM, Koepsell H.
    J Biol Chem; 2005 Jul 01; 280(26):24481-90. PubMed ID: 15878879
    [Abstract] [Full Text] [Related]

  • 7. The organic cation transporters rOCT1 and hOCT2 are inhibited by cGMP.
    Schlatter E, Mönnich V, Cetinkaya I, Mehrens T, Ciarimboli G, Hirsch JR, Popp C, Koepsell H.
    J Membr Biol; 2002 Oct 01; 189(3):237-44. PubMed ID: 12395288
    [Abstract] [Full Text] [Related]

  • 8. Amino acids critical for substrate affinity of rat organic cation transporter 1 line the substrate binding region in a model derived from the tertiary structure of lactose permease.
    Popp C, Gorboulev V, Müller TD, Gorbunov D, Shatskaya N, Koepsell H.
    Mol Pharmacol; 2005 May 01; 67(5):1600-11. PubMed ID: 15662044
    [Abstract] [Full Text] [Related]

  • 9. Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs.
    Urakami Y, Okuda M, Masuda S, Saito H, Inui KI.
    J Pharmacol Exp Ther; 1998 Nov 01; 287(2):800-5. PubMed ID: 9808712
    [Abstract] [Full Text] [Related]

  • 10. Molecular mechanisms of organic cation transport in OCT2-expressing Xenopus oocytes.
    Okuda M, Urakami Y, Saito H, Inui K.
    Biochim Biophys Acta; 1999 Mar 04; 1417(2):224-31. PubMed ID: 10082798
    [Abstract] [Full Text] [Related]

  • 11. High-affinity cation binding to organic cation transporter 1 induces movement of helix 11 and blocks transport after mutations in a modeled interaction domain between two helices.
    Gorbunov D, Gorboulev V, Shatskaya N, Mueller T, Bamberg E, Friedrich T, Koepsell H.
    Mol Pharmacol; 2008 Jan 04; 73(1):50-61. PubMed ID: 17940192
    [Abstract] [Full Text] [Related]

  • 12. Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations.
    Yabuuchi H, Tamai I, Nezu J, Sakamoto K, Oku A, Shimane M, Sai Y, Tsuji A.
    J Pharmacol Exp Ther; 1999 May 04; 289(2):768-73. PubMed ID: 10215651
    [Abstract] [Full Text] [Related]

  • 13. The neurotoxin 1-methyl-4-phenylpyridinium is a substrate for the canalicular organic cation/H+ exchanger.
    Moseley RH, Zugger LJ, Van Dyke RW.
    J Pharmacol Exp Ther; 1997 Apr 04; 281(1):34-40. PubMed ID: 9103477
    [Abstract] [Full Text] [Related]

  • 14. Mutation of amino acid 475 of rat organic cation transporter 2 (rOCT2) impairs organic cation transport.
    Bahn A, Hagos Y, Rudolph T, Burckhardt G.
    Biochimie; 2004 Feb 04; 86(2):133-6. PubMed ID: 15016452
    [Abstract] [Full Text] [Related]

  • 15. Functional roles of cationic amino acid residues in the sodium-dicarboxylate cotransporter 3 (NaDC-3) from winter flounder.
    Hagos Y, Steffgen J, Rizwan AN, Langheit D, Knoll A, Burckhardt G, Burckhardt BC.
    Am J Physiol Renal Physiol; 2006 Dec 04; 291(6):F1224-31. PubMed ID: 16735460
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  • 19. Substrate- and cell contact-dependent inhibitor affinity of human organic cation transporter 2: studies with two classical organic cation substrates and the novel substrate cd2+.
    Thévenod F, Ciarimboli G, Leistner M, Wolff NA, Lee WK, Schatz I, Keller T, Al-Monajjed R, Gorboulev V, Koepsell H.
    Mol Pharm; 2013 Aug 05; 10(8):3045-56. PubMed ID: 23763587
    [Abstract] [Full Text] [Related]

  • 20. Transport of the dopamine D2 agonist pramipexole by rat organic cation transporters OCT1 and OCT2 in kidney.
    Ishiguro N, Saito A, Yokoyama K, Morikawa M, Igarashi T, Tamai I.
    Drug Metab Dispos; 2005 Apr 05; 33(4):495-9. PubMed ID: 15640376
    [Abstract] [Full Text] [Related]

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