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Journal Abstract Search

309 related items for PubMed ID: 19220018

  • 1. 10-(2-oxo-2-phenylethylidene)-10H-anthracen-9-ones as highly active antimicrotubule agents: synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Prinz H, Schmidt P, Böhm KJ, Baasner S, Müller K, Unger E, Gerlach M, Günther EG.
    J Med Chem; 2009 Mar 12; 52(5):1284-94. PubMed ID: 19220018
    [Abstract] [Full Text] [Related]

  • 2. Sulfonate derivatives of naphtho[2,3-b]thiophen-4(9H)-one and 9(10H)-anthracenone as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Zuse A, Schmidt P, Baasner S, Böhm KJ, Müller K, Gerlach M, Günther EG, Unger E, Prinz H.
    J Med Chem; 2007 Nov 29; 50(24):6059-66. PubMed ID: 17973361
    [Abstract] [Full Text] [Related]

  • 3. Phenylimino-10H-anthracen-9-ones as novel antimicrotubule agents-synthesis, antiproliferative activity and inhibition of tubulin polymerization.
    Prinz H, Schmidt P, Böhm KJ, Baasner S, Müller K, Gerlach M, Günther EG, Unger E.
    Bioorg Med Chem; 2011 Jul 15; 19(14):4183-91. PubMed ID: 21705223
    [Abstract] [Full Text] [Related]

  • 4. Synthesis, antiproliferative activity and inhibition of tubulin polymerization by 1,5- and 1,8-disubstituted 10H-anthracen-9-ones bearing a 10-benzylidene or 10-(2-oxo-2-phenylethylidene) moiety.
    Nickel HC, Schmidt P, Böhm KJ, Baasner S, Müller K, Gerlach M, Unger E, Günther EG, Prinz H.
    Eur J Med Chem; 2010 Aug 15; 45(8):3420-38. PubMed ID: 20537765
    [Abstract] [Full Text] [Related]

  • 5. 9-Benzylidene-naphtho[2,3-b]thiophen-4-ones as novel antimicrotubule agents-synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Zuse A, Schmidt P, Baasner S, Böhm KJ, Müller K, Gerlach M, Günther EG, Unger E, Prinz H.
    J Med Chem; 2006 Dec 28; 49(26):7816-25. PubMed ID: 17181164
    [Abstract] [Full Text] [Related]

  • 6. Novel benzylidene-9(10H)-anthracenones as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Prinz H, Ishii Y, Hirano T, Stoiber T, Camacho Gomez JA, Schmidt P, Düssmann H, Burger AM, Prehn JH, Günther EG, Unger E, Umezawa K.
    J Med Chem; 2003 Jul 17; 46(15):3382-94. PubMed ID: 12852768
    [Abstract] [Full Text] [Related]

  • 7. 5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors.
    Nien CY, Chen YC, Kuo CC, Hsieh HP, Chang CY, Wu JS, Wu SY, Liou JP, Chang JY.
    J Med Chem; 2010 Mar 11; 53(5):2309-13. PubMed ID: 20148562
    [Abstract] [Full Text] [Related]

  • 8. 4- and 5-aroylindoles as novel classes of potent antitubulin agents.
    Liou JP, Wu CY, Hsieh HP, Chang CY, Chen CM, Kuo CC, Chang JY.
    J Med Chem; 2007 Sep 06; 50(18):4548-52. PubMed ID: 17685504
    [Abstract] [Full Text] [Related]

  • 9. 2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
    Chang JY, Yang MF, Chang CY, Chen CM, Kuo CC, Liou JP.
    J Med Chem; 2006 Oct 19; 49(21):6412-5. PubMed ID: 17034147
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and biological evaluation of 2,4,5-substituted pyrimidines as a new class of tubulin polymerization inhibitors.
    Xie F, Zhao H, Li D, Chen H, Quan H, Shi X, Lou L, Hu Y.
    J Med Chem; 2011 May 12; 54(9):3200-5. PubMed ID: 21480626
    [Abstract] [Full Text] [Related]

  • 11. N-benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Prinz H, Chamasmani B, Vogel K, Böhm KJ, Aicher B, Gerlach M, Günther EG, Amon P, Ivanov I, Müller K.
    J Med Chem; 2011 Jun 23; 54(12):4247-63. PubMed ID: 21563750
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents.
    Romagnoli R, Baraldi PG, Pavani MG, Tabrizi MA, Preti D, Fruttarolo F, Piccagli L, Jung MK, Hamel E, Borgatti M, Gambari R.
    J Med Chem; 2006 Jun 29; 49(13):3906-15. PubMed ID: 16789746
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and biological evaluation of 2- and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization.
    Romagnoli R, Baraldi PG, Carrion MD, Lopez Cara C, Preti D, Fruttarolo F, Pavani MG, Tabrizi MA, Tolomeo M, Grimaudo S, Di Cristina A, Balzarini J, Hadfield JA, Brancale A, Hamel E.
    J Med Chem; 2007 May 03; 50(9):2273-7. PubMed ID: 17419607
    [Abstract] [Full Text] [Related]

  • 14. 7-Aroyl-aminoindoline-1-sulfonamides as a novel class of potent antitubulin agents.
    Chang JY, Hsieh HP, Chang CY, Hsu KS, Chiang YF, Chen CM, Kuo CC, Liou JP.
    J Med Chem; 2006 Nov 16; 49(23):6656-9. PubMed ID: 17154496
    [Abstract] [Full Text] [Related]

  • 15. Design, synthesis, and biological evaluation of thiophene analogues of chalcones.
    Romagnoli R, Baraldi PG, Carrion MD, Cara CL, Cruz-Lopez O, Preti D, Tolomeo M, Grimaudo S, Di Cristina A, Zonta N, Balzarini J, Brancale A, Sarkar T, Hamel E.
    Bioorg Med Chem; 2008 May 15; 16(10):5367-76. PubMed ID: 18440234
    [Abstract] [Full Text] [Related]

  • 16. [4-(imidazol-1-yl)thiazol-2-yl]phenylamines. A novel class of highly potent colchicine site binding tubulin inhibitors: synthesis and cytotoxic activity on selected human cancer cell lines.
    Mahboobi S, Sellmer A, Höcher H, Eichhorn E, Bär T, Schmidt M, Maier T, Stadlwieser JF, Beckers TL.
    J Med Chem; 2006 Sep 21; 49(19):5769-76. PubMed ID: 16970401
    [Abstract] [Full Text] [Related]

  • 17. 2-aroylindoles, a novel class of potent, orally active small molecule tubulin inhibitors.
    Beckers T, Reissmann T, Schmidt M, Burger AM, Fiebig HH, Vanhoefer U, Pongratz H, Hufsky H, Hockemeyer J, Frieser M, Mahboobi S.
    Cancer Res; 2002 Jun 01; 62(11):3113-9. PubMed ID: 12036922
    [Abstract] [Full Text] [Related]

  • 18. Potent antitubulin tumor cell cytotoxins based on 3-aroyl indazoles.
    Duan JX, Cai X, Meng F, Lan L, Hart C, Matteucci M.
    J Med Chem; 2007 Mar 08; 50(5):1001-6. PubMed ID: 17286393
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents.
    Reddy GR, Kuo CC, Tan UK, Coumar MS, Chang CY, Chiang YK, Lai MJ, Yeh JY, Wu SY, Chang JY, Liou JP, Hsieh HP.
    J Med Chem; 2008 Dec 25; 51(24):8163-7. PubMed ID: 19053773
    [Abstract] [Full Text] [Related]

  • 20. New C5-alkylated indolobenzazepinones acting as inhibitors of tubulin polymerization: cytotoxic and antitumor activities.
    Keller L, Beaumont S, Liu JM, Thoret S, Bignon JS, Wdzieczak-Bakala J, Dauban P, Dodd RH.
    J Med Chem; 2008 Jun 26; 51(12):3414-21. PubMed ID: 18503262
    [Abstract] [Full Text] [Related]

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