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Journal Abstract Search

231 related items for PubMed ID: 19222480

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  • 7. Ventricular remodelling is a prerequisite for the induction of dofetilide-induced torsade de pointes arrhythmias in the anaesthetized, complete atrio-ventricular-block dog.
    Dunnink A, van Opstal JM, Oosterhoff P, Winckels SK, Beekman JD, van der Nagel R, Cora Verduyn S, Vos MA.
    Europace; 2012 Mar; 14(3):431-6. PubMed ID: 21946817
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  • 8. Inhibition of the Na+/Ca2+ exchanger suppresses torsades de pointes in an intact heart model of long QT syndrome-2 and long QT syndrome-3.
    Milberg P, Pott C, Fink M, Frommeyer G, Matsuda T, Baba A, Osada N, Breithardt G, Noble D, Eckardt L.
    Heart Rhythm; 2008 Oct; 5(10):1444-52. PubMed ID: 18929333
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  • 9. Calcium antagonist property of CPU228, a dofetilide derivative, contributes to its low incidence of torsades de pointes in rabbits.
    Huang ZJ, Dai DZ, Li N, Na T, Ji M, Dai Y.
    Clin Exp Pharmacol Physiol; 2007 Apr; 34(4):310-7. PubMed ID: 17324143
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  • 10. Beat-by-beat QT interval variability, but not QT prolongation per se, predicts drug-induced torsades de pointes in the anaesthetised methoxamine-sensitized rabbit.
    Jacobson I, Carlsson L, Duker G.
    J Pharmacol Toxicol Methods; 2011 Apr; 63(1):40-6. PubMed ID: 20451633
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  • 11. New in vitro model for proarrhythmia safety screening: IKs inhibition potentiates the QTc prolonging effect of IKr inhibitors in isolated guinea pig hearts.
    Kui P, Orosz S, Takács H, Sarusi A, Csík N, Rárosi F, Csekő C, Varró A, Papp JG, Forster T, Farkas AS, Farkas A.
    J Pharmacol Toxicol Methods; 2016 Apr; 80():26-34. PubMed ID: 27063345
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  • 12. Combined pharmacological block of I(Kr) and I(Ks) increases short-term QT interval variability and provokes torsades de pointes.
    Lengyel C, Varró A, Tábori K, Papp JG, Baczkó I.
    Br J Pharmacol; 2007 Aug; 151(7):941-51. PubMed ID: 17533421
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  • 15. Assessment of the proarrhythmic potential of the novel antiarrhythmic agent AZD7009 and dofetilide in experimental models of torsades de pointes.
    Wu Y, Carlsson L, Liu T, Kowey PR, Yan GX.
    J Cardiovasc Electrophysiol; 2005 Aug; 16(8):898-904. PubMed ID: 16101634
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  • 16. Assessment of efficacy of proarrhythmia biomarkers in isolated rabbit hearts with attenuated repolarization reserve.
    Orosz S, Sarusi A, Csík N, Papp JG, Varró A, Farkas S, Forster T, Farkas AS, Farkas A.
    J Cardiovasc Pharmacol; 2014 Sep; 64(3):266-76. PubMed ID: 24887684
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  • 17. Biomarkers and endogenous determinants of dofetilide-induced torsades de pointes in α(1) -adrenoceptor-stimulated, anaesthetized rabbits.
    Farkas AS, Rudas L, Makra P, Csík N, Leprán I, Forster T, Csanády M, Papp JG, Varró A, Farkas A.
    Br J Pharmacol; 2010 Dec; 161(7):1477-95. PubMed ID: 20659107
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  • 18. Slow delayed rectifier K+ current block by HMR 1556 increases dispersion of repolarization and promotes Torsades de Pointes in rabbit ventricles.
    So PP, Backx PH, Dorian P.
    Br J Pharmacol; 2008 Dec; 155(8):1185-94. PubMed ID: 18836478
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  • 19. Potentially modifiable factors of dofetilide-associated risk of torsades de pointes among hospitalized patients with atrial fibrillation.
    Naksuk N, Sugrue AM, Padmanabhan D, Kella D, DeSimone CV, Kapa S, Asirvatham SJ, Lee HC, Ackerman MJ, Noseworthy PA.
    J Interv Card Electrophysiol; 2019 Mar; 54(2):189-196. PubMed ID: 30353374
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  • 20. The electromechanical window is no better than QT prolongation to assess risk of Torsade de Pointes in the complete atrioventricular block model in dogs.
    Stams TR, Bourgonje VJ, Beekman HD, Schoenmakers M, van der Nagel R, Oosterhoff P, van Opstal JM, Vos MA.
    Br J Pharmacol; 2014 Feb; 171(3):714-22. PubMed ID: 24490860
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