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Journal Abstract Search

145 related items for PubMed ID: 19223492

  • 1. Suppression of tumor growth in vivo by the mitocan alpha-tocopheryl succinate requires respiratory complex II.
    Dong LF, Freeman R, Liu J, Zobalova R, Marin-Hernandez A, Stantic M, Rohlena J, Valis K, Rodriguez-Enriquez S, Butcher B, Goodwin J, Brunk UT, Witting PK, Moreno-Sanchez R, Scheffler IE, Ralph SJ, Neuzil J.
    Clin Cancer Res; 2009 Mar 01; 15(5):1593-600. PubMed ID: 19223492
    [Abstract] [Full Text] [Related]

  • 2. (+)α-Tocopheryl succinate inhibits the mitochondrial respiratory chain complex I and is as effective as arsenic trioxide or ATRA against acute promyelocytic leukemia in vivo.
    dos Santos GA, Abreu e Lima RS, Pestana CR, Lima AS, Scheucher PS, Thomé CH, Gimenes-Teixeira HL, Santana-Lemos BA, Lucena-Araujo AR, Rodrigues FP, Nasr R, Uyemura SA, Falcão RP, de Thé H, Pandolfi PP, Curti C, Rego EM.
    Leukemia; 2012 Mar 01; 26(3):451-60. PubMed ID: 21869839
    [Abstract] [Full Text] [Related]

  • 3. Alpha-tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II.
    Dong LF, Low P, Dyason JC, Wang XF, Prochazka L, Witting PK, Freeman R, Swettenham E, Valis K, Liu J, Zobalova R, Turanek J, Spitz DR, Domann FE, Scheffler IE, Ralph SJ, Neuzil J.
    Oncogene; 2008 Jul 17; 27(31):4324-35. PubMed ID: 18372923
    [Abstract] [Full Text] [Related]

  • 4. Mitochondrial targeting of α-tocopheryl succinate enhances its anti-mesothelioma efficacy.
    Kovarova J, Bajzikova M, Vondrusova M, Stursa J, Goodwin J, Nguyen M, Zobalova R, Pesdar EA, Truksa J, Tomasetti M, Dong LF, Neuzil J.
    Redox Rep; 2014 Jan 17; 19(1):16-25. PubMed ID: 24225203
    [Abstract] [Full Text] [Related]

  • 5. Mitochondrial targeting of vitamin E succinate enhances its pro-apoptotic and anti-cancer activity via mitochondrial complex II.
    Dong LF, Jameson VJ, Tilly D, Cerny J, Mahdavian E, Marín-Hernández A, Hernández-Esquivel L, Rodríguez-Enríquez S, Stursa J, Witting PK, Stantic B, Rohlena J, Truksa J, Kluckova K, Dyason JC, Ledvina M, Salvatore BA, Moreno-Sánchez R, Coster MJ, Ralph SJ, Smith RA, Neuzil J.
    J Biol Chem; 2011 Feb 04; 286(5):3717-28. PubMed ID: 21059645
    [Abstract] [Full Text] [Related]

  • 6. Tocopheramine succinate and tocopheryl succinate: mechanism of mitochondrial inhibition and superoxide radical production.
    Gruber J, Staniek K, Krewenka C, Moldzio R, Patel A, Böhmdorfer S, Rosenau T, Gille L.
    Bioorg Med Chem; 2014 Jan 15; 22(2):684-91. PubMed ID: 24393721
    [Abstract] [Full Text] [Related]

  • 7. Reactive oxygen species are generated by the respiratory complex II--evidence for lack of contribution of the reverse electron flow in complex I.
    Moreno-Sánchez R, Hernández-Esquivel L, Rivero-Segura NA, Marín-Hernández A, Neuzil J, Ralph SJ, Rodríguez-Enríquez S.
    FEBS J; 2013 Feb 15; 280(3):927-38. PubMed ID: 23206332
    [Abstract] [Full Text] [Related]

  • 8. α-Tocopheryloxyacetic acid is superior to α-tocopheryl succinate in suppressing HER2-high breast carcinomas due to its higher stability.
    Dong LF, Grant G, Massa H, Zobalova R, Akporiaye E, Neuzil J.
    Int J Cancer; 2012 Sep 01; 131(5):1052-8. PubMed ID: 22038845
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of mitochondrial glycerol-3-phosphate dehydrogenase by α-tocopheryl succinate.
    Rauchová H, Vokurková M, Drahota Z.
    Int J Biochem Cell Biol; 2014 Aug 01; 53():409-13. PubMed ID: 24953557
    [Abstract] [Full Text] [Related]

  • 10. Vitamin E succinate is a potent novel antineoplastic agent with high selectivity and cooperativity with tumor necrosis factor-related apoptosis-inducing ligand (Apo2 ligand) in vivo.
    Weber T, Lu M, Andera L, Lahm H, Gellert N, Fariss MW, Korinek V, Sattler W, Ucker DS, Terman A, Schröder A, Erl W, Brunk UT, Coffey RJ, Weber C, Neuzil J.
    Clin Cancer Res; 2002 Mar 01; 8(3):863-9. PubMed ID: 11895920
    [Abstract] [Full Text] [Related]

  • 11. The role of alpha tocopheryl succinate (α-TOS) as a potential anticancer agent.
    Angulo-Molina A, Reyes-Leyva J, López-Malo A, Hernández J.
    Nutr Cancer; 2014 Mar 01; 66(2):167-76. PubMed ID: 24364743
    [Abstract] [Full Text] [Related]

  • 12. Affinity of vitamin E analogues for the ubiquinone complex II site correlates with their toxicity to cancer cells.
    Neuzil J, Cerny J, Dyason JC, Dong LF, Ralph SJ.
    Mol Nutr Food Res; 2011 Oct 01; 55(10):1543-51. PubMed ID: 21656671
    [Abstract] [Full Text] [Related]

  • 13. alpha-Tocopheryl succinate causes mitochondrial permeabilization by preferential formation of Bak channels.
    Prochazka L, Dong LF, Valis K, Freeman R, Ralph SJ, Turanek J, Neuzil J.
    Apoptosis; 2010 Jul 01; 15(7):782-94. PubMed ID: 20217235
    [Abstract] [Full Text] [Related]

  • 14. Role of reactive oxygen species in the induction of apoptosis by alpha-tocopheryl succinate.
    Kang YH, Lee E, Choi MK, Ku JL, Kim SH, Park YG, Lim SJ.
    Int J Cancer; 2004 Nov 10; 112(3):385-92. PubMed ID: 15382062
    [Abstract] [Full Text] [Related]

  • 15. Alpha-tocopheryl succinate (alpha-TOS) modulates human prostate LNCaP xenograft growth and gene expression in BALB/c nude mice fed two levels of dietary soybean oil.
    Basu A, Grossie B, Bennett M, Mills N, Imrhan V.
    Eur J Nutr; 2007 Feb 10; 46(1):34-43. PubMed ID: 17180484
    [Abstract] [Full Text] [Related]

  • 16. Vitamin E analogues as inducers of apoptosis: implications for their potential antineoplastic role.
    Neuzil J, Weber T, Terman A, Weber C, Brunk UT.
    Redox Rep; 2001 Feb 10; 6(3):143-51. PubMed ID: 11523588
    [Abstract] [Full Text] [Related]

  • 17. Hysteresis and bistability in the succinate-CoQ reductase activity and reactive oxygen species production in the mitochondrial respiratory complex II.
    Markevich NI, Galimova MH, Markevich LN.
    Redox Biol; 2020 Oct 10; 37():101630. PubMed ID: 32747163
    [Abstract] [Full Text] [Related]

  • 18. α-Tocopheryl succinate-suppressed development of cerebral malaria in mice.
    Kume A, Kasai S, Furuya H, Suzuki H.
    Parasitol Res; 2018 Oct 10; 117(10):3177-3182. PubMed ID: 30030625
    [Abstract] [Full Text] [Related]

  • 19. Emodin induces apoptosis of lung cancer cells through ER stress and the TRIB3/NF-κB pathway.
    Su J, Yan Y, Qu J, Xue X, Liu Z, Cai H.
    Oncol Rep; 2017 Mar 10; 37(3):1565-1572. PubMed ID: 28184934
    [Abstract] [Full Text] [Related]

  • 20. Mitochondrial complex II and reactive oxygen species in disease and therapy.
    Hadrava Vanova K, Kraus M, Neuzil J, Rohlena J.
    Redox Rep; 2020 Dec 10; 25(1):26-32. PubMed ID: 32290794
    [Abstract] [Full Text] [Related]

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