These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

604 related items for PubMed ID: 19233513

  • 1. Thiamine deficiency increases β-secretase activity and accumulation of β-amyloid peptides.
    Zhang Q, Yang G, Li W, Fan Z, Sun A, Luo J, Ke ZJ.
    Neurobiol Aging; 2011 Jan; 32(1):42-53. PubMed ID: 19233513
    [Abstract] [Full Text] [Related]

  • 2. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y, Wang Z, Wang R, Zhang X, Zhang S, Wu Y, Staufenbiel M, Cai F, Song W.
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [Abstract] [Full Text] [Related]

  • 3. Amyloid-β₄₂ activates the expression of BACE1 through the JNK pathway.
    Guglielmotto M, Monteleone D, Giliberto L, Fornaro M, Borghi R, Tamagno E, Tabaton M.
    J Alzheimers Dis; 2011 Jun; 27(4):871-83. PubMed ID: 21897006
    [Abstract] [Full Text] [Related]

  • 4. Decrease in brain soluble amyloid precursor protein β (sAPPβ) in Alzheimer's disease cortex.
    Wu G, Sankaranarayanan S, Hsieh SH, Simon AJ, Savage MJ.
    J Neurosci Res; 2011 Jun; 89(6):822-32. PubMed ID: 21433051
    [Abstract] [Full Text] [Related]

  • 5. In vivo beta-secretase 1 inhibition leads to brain Abeta lowering and increased alpha-secretase processing of amyloid precursor protein without effect on neuregulin-1.
    Sankaranarayanan S, Price EA, Wu G, Crouthamel MC, Shi XP, Tugusheva K, Tyler KX, Kahana J, Ellis J, Jin L, Steele T, Stachel S, Coburn C, Simon AJ.
    J Pharmacol Exp Ther; 2008 Mar; 324(3):957-69. PubMed ID: 18156464
    [Abstract] [Full Text] [Related]

  • 6. Presenilin 1 is involved in the maturation of beta-site amyloid precursor protein-cleaving enzyme 1 (BACE1).
    Kuzuya A, Uemura K, Kitagawa N, Aoyagi N, Kihara T, Ninomiya H, Ishiura S, Takahashi R, Shimohama S.
    J Neurosci Res; 2007 Jan; 85(1):153-65. PubMed ID: 17075903
    [Abstract] [Full Text] [Related]

  • 7. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
    Evin G, Zhu A, Holsinger RM, Masters CL, Li QX.
    J Neurosci Res; 2003 Nov 01; 74(3):386-92. PubMed ID: 14598315
    [Abstract] [Full Text] [Related]

  • 8. S-Adenosylhomocysteine increases beta-amyloid formation in BV-2 microglial cells by increased expressions of beta-amyloid precursor protein and presenilin 1 and by hypomethylation of these gene promoters.
    Lin HC, Hsieh HM, Chen YH, Hu ML.
    Neurotoxicology; 2009 Jul 01; 30(4):622-7. PubMed ID: 19635394
    [Abstract] [Full Text] [Related]

  • 9. Immunomodulation of AβPP processing alleviates amyloid-β-related pathology in Alzheimer's disease transgenic mice.
    Arbel-Ornath M, Becker M, Rabinovich-Toidman P, Gartner M, Solomon B.
    J Alzheimers Dis; 2010 Jul 01; 22(2):469-82. PubMed ID: 20847413
    [Abstract] [Full Text] [Related]

  • 10. The Swedish APP mutation alters the effect of genetically reduced BACE1 expression on the APP processing.
    Rabe S, Reichwald J, Ammaturo D, de Strooper B, Saftig P, Neumann U, Staufenbiel M.
    J Neurochem; 2011 Oct 01; 119(1):231-9. PubMed ID: 21812781
    [Abstract] [Full Text] [Related]

  • 11. The proteins BACE1 and BACE2 and beta-secretase activity in normal and Alzheimer's disease brain.
    Stockley JH, O'Neill C.
    Biochem Soc Trans; 2007 Jun 01; 35(Pt 3):574-6. PubMed ID: 17511655
    [Abstract] [Full Text] [Related]

  • 12. Effects of galantamine on β-amyloid release and beta-site cleaving enzyme 1 expression in differentiated human neuroblastoma SH-SY5Y cells.
    Li Q, Wu D, Zhang L, Zhang Y.
    Exp Gerontol; 2010 Nov 01; 45(11):842-7. PubMed ID: 20600777
    [Abstract] [Full Text] [Related]

  • 13. Proteasome-mediated effects on amyloid precursor protein processing at the gamma-secretase site.
    Flood F, Murphy S, Cowburn RF, Lannfelt L, Walker B, Johnston JA.
    Biochem J; 2005 Jan 15; 385(Pt 2):545-50. PubMed ID: 15473868
    [Abstract] [Full Text] [Related]

  • 14. Oral administration of a potent and selective non-peptidic BACE-1 inhibitor decreases beta-cleavage of amyloid precursor protein and amyloid-beta production in vivo.
    Hussain I, Hawkins J, Harrison D, Hille C, Wayne G, Cutler L, Buck T, Walter D, Demont E, Howes C, Naylor A, Jeffrey P, Gonzalez MI, Dingwall C, Michel A, Redshaw S, Davis JB.
    J Neurochem; 2007 Feb 15; 100(3):802-9. PubMed ID: 17156133
    [Abstract] [Full Text] [Related]

  • 15. The novel beta-secretase inhibitor KMI-429 reduces amyloid beta peptide production in amyloid precursor protein transgenic and wild-type mice.
    Asai M, Hattori C, Iwata N, Saido TC, Sasagawa N, Szabó B, Hashimoto Y, Maruyama K, Tanuma S, Kiso Y, Ishiura S.
    J Neurochem; 2006 Jan 15; 96(2):533-40. PubMed ID: 16336629
    [Abstract] [Full Text] [Related]

  • 16. Inhibiting β-secretase activity in Alzheimer's disease cell models with single-chain antibodies specifically targeting APP.
    Boddapati S, Levites Y, Sierks MR.
    J Mol Biol; 2011 Jan 14; 405(2):436-47. PubMed ID: 21073877
    [Abstract] [Full Text] [Related]

  • 17. P-glycoprotein efflux and other factors limit brain amyloid beta reduction by beta-site amyloid precursor protein-cleaving enzyme 1 inhibitors in mice.
    Meredith JE, Thompson LA, Toyn JH, Marcin L, Barten DM, Marcinkeviciene J, Kopcho L, Kim Y, Lin A, Guss V, Burton C, Iben L, Polson C, Cantone J, Ford M, Drexler D, Fiedler T, Lentz KA, Grace JE, Kolb J, Corsa J, Pierdomenico M, Jones K, Olson RE, Macor JE, Albright CF.
    J Pharmacol Exp Ther; 2008 Aug 14; 326(2):502-13. PubMed ID: 18499745
    [Abstract] [Full Text] [Related]

  • 18. Thiamine deficiency induces oxidative stress and exacerbates the plaque pathology in Alzheimer's mouse model.
    Karuppagounder SS, Xu H, Shi Q, Chen LH, Pedrini S, Pechman D, Baker H, Beal MF, Gandy SE, Gibson GE.
    Neurobiol Aging; 2009 Oct 14; 30(10):1587-600. PubMed ID: 18406011
    [Abstract] [Full Text] [Related]

  • 19. IGF-1 promotes beta-amyloid production by a secretase-independent mechanism.
    Araki W, Kume H, Oda A, Tamaoka A, Kametani F.
    Biochem Biophys Res Commun; 2009 Feb 27; 380(1):111-4. PubMed ID: 19167357
    [Abstract] [Full Text] [Related]

  • 20. RAGE regulates BACE1 and Abeta generation via NFAT1 activation in Alzheimer's disease animal model.
    Cho HJ, Son SM, Jin SM, Hong HS, Shin DH, Kim SJ, Huh K, Mook-Jung I.
    FASEB J; 2009 Aug 27; 23(8):2639-49. PubMed ID: 19332646
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 31.