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Journal Abstract Search

609 related items for PubMed ID: 19243697

  • 1. The anti-inflammatory effects of ZLJ-6, a novel dual cyclooxygenase/5-lipoxygenase inhibitor.
    Li L, Ji H, Sheng L, Zhang Y, Lai Y, Chen X.
    Eur J Pharmacol; 2009 Apr 01; 607(1-3):244-50. PubMed ID: 19243697
    [Abstract] [Full Text] [Related]

  • 2. Tepoxalin: a dual cyclooxygenase/5-lipoxygenase inhibitor of arachidonic acid metabolism with potent anti-inflammatory activity and a favorable gastrointestinal profile.
    Argentieri DC, Ritchie DM, Ferro MP, Kirchner T, Wachter MP, Anderson DW, Rosenthale ME, Capetola RJ.
    J Pharmacol Exp Ther; 1994 Dec 01; 271(3):1399-408. PubMed ID: 7996452
    [Abstract] [Full Text] [Related]

  • 3. Rofecoxib [Vioxx, MK-0966; 4-(4'-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: a potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles.
    Chan CC, Boyce S, Brideau C, Charleson S, Cromlish W, Ethier D, Evans J, Ford-Hutchinson AW, Forrest MJ, Gauthier JY, Gordon R, Gresser M, Guay J, Kargman S, Kennedy B, Leblanc Y, Leger S, Mancini J, O'Neill GP, Ouellet M, Patrick D, Percival MD, Perrier H, Prasit P, Rodger I.
    J Pharmacol Exp Ther; 1999 Aug 01; 290(2):551-60. PubMed ID: 10411562
    [Abstract] [Full Text] [Related]

  • 4. Aegiceras corniculatum extract suppresses initial and late phases of inflammation in rat paw and attenuates the production of eicosanoids in rat neutrophils and human platelets.
    Roome T, Dar A, Naqvi S, Ali S, Choudhary MI.
    J Ethnopharmacol; 2008 Nov 20; 120(2):248-54. PubMed ID: 18809484
    [Abstract] [Full Text] [Related]

  • 5. Preclinical pharmacology profile of CS-706, a novel cyclooxygenase-2 selective inhibitor, with potent antinociceptive and anti-inflammatory effects.
    Ushiyama S, Yamada T, Murakami Y, Kumakura S, Inoue S, Suzuki K, Nakao A, Kawara A, Kimura T.
    Eur J Pharmacol; 2008 Jan 06; 578(1):76-86. PubMed ID: 17920584
    [Abstract] [Full Text] [Related]

  • 6. Evaluation of the antiinflammatory activity of a dual cyclooxygenase-2 selective/5-lipoxygenase inhibitor, RWJ 63556, in a canine model of inflammation.
    Kirchner T, Argentieri DC, Barbone AG, Singer M, Steber M, Ansell J, Beers SA, Wachter MP, Wu W, Malloy E, Stewart A, Ritchie DM.
    J Pharmacol Exp Ther; 1997 Aug 06; 282(2):1094-101. PubMed ID: 9262379
    [Abstract] [Full Text] [Related]

  • 7. Tenidap inhibits 5-lipoxygenase product formation in vitro, but this activity is not observed in three animal models.
    Carty TJ, Sweeney FJ, Griffiths RJ, Eskra JD, Ernest MJ, Pillar JS, Cheng JD, Loose LD, Joseph PA, Pazoles PP, Moore PF, Nagahisa A, Murase S, Kadin SB.
    Inflamm Res; 1997 May 06; 46(5):168-79. PubMed ID: 9197987
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of lipoxygenases and cyclooxygenase-2 enzymes by extracts isolated from Bacopa monniera (L.) Wettst.
    Viji V, Helen A.
    J Ethnopharmacol; 2008 Jul 23; 118(2):305-11. PubMed ID: 18534796
    [Abstract] [Full Text] [Related]

  • 9. Discovery of a novel COX-2 inhibitor as an orally potent anti-pyretic and anti-inflammatory drug: design, synthesis, and structure-activity relationship.
    Hayashi S, Sumi Y, Ueno N, Murase A, Takada J.
    Biochem Pharmacol; 2011 Oct 01; 82(7):755-68. PubMed ID: 21741371
    [Abstract] [Full Text] [Related]

  • 10. Etoricoxib (MK-0663): preclinical profile and comparison with other agents that selectively inhibit cyclooxygenase-2.
    Riendeau D, Percival MD, Brideau C, Charleson S, Dubé D, Ethier D, Falgueyret JP, Friesen RW, Gordon R, Greig G, Guay J, Mancini J, Ouellet M, Wong E, Xu L, Boyce S, Visco D, Girard Y, Prasit P, Zamboni R, Rodger IW, Gresser M, Ford-Hutchinson AW, Young RN, Chan CC.
    J Pharmacol Exp Ther; 2001 Feb 01; 296(2):558-66. PubMed ID: 11160644
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and biological evaluation of a novel class of rofecoxib analogues as dual inhibitors of cyclooxygenases (COXs) and lipoxygenases (LOXs).
    Chen QH, Rao PN, Knaus EE.
    Bioorg Med Chem; 2006 Dec 01; 14(23):7898-909. PubMed ID: 16904331
    [Abstract] [Full Text] [Related]

  • 12. CC 05, a novel anti-inflammatory compound, exerts its effect by inhibition of cyclooxygenase-2 activity.
    Yin LL, Zhang WY, Li MH, Shen JK, Zhu XZ.
    Eur J Pharmacol; 2005 Sep 27; 520(1-3):172-8. PubMed ID: 16168408
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases.
    Rao PN, Chen QH, Knaus EE.
    J Med Chem; 2006 Mar 09; 49(5):1668-83. PubMed ID: 16509583
    [Abstract] [Full Text] [Related]

  • 14. In vitro effects of E3040, a dual inhibitor of 5-lipoxygenase and thromboxane A(2) synthetase, on eicosanoid production.
    Oketani K, Nagakura N, Harada K, Inoue T.
    Eur J Pharmacol; 2001 Jun 22; 422(1-3):209-16. PubMed ID: 11430933
    [Abstract] [Full Text] [Related]

  • 15. ER-34122, a novel dual 5-lipoxygenase/cyclooxygenase inhibitor with potent anti-inflammatory activity in an arachidonic acid-induced ear inflammation model.
    Horizoe T, Nagakura N, Chiba K, Shirota H, Shinoda M, Kobayashi N, Numata H, Okamoto Y, Kobayashi S.
    Inflamm Res; 1998 Oct 22; 47(10):375-83. PubMed ID: 9831321
    [Abstract] [Full Text] [Related]

  • 16. The different inhibitory effects of Huang-Lian-Jie-Du-Tang on cyclooxygenase 2 and 5-lipoxygenase.
    Li L, Zeng H, Shan L, Yuan X, Li Y, Liu R, Zhang W.
    J Ethnopharmacol; 2012 Sep 28; 143(2):732-9. PubMed ID: 22884869
    [Abstract] [Full Text] [Related]

  • 17. Preclinical pharmacokinetic and pharmacodynamic evaluation of thiazolidinone PG15: an anti-inflammatory candidate.
    Uchôa Fde T, da Silva TG, de Lima Mdo C, Galdino SL, Pitta Ida R, Dalla Costa T.
    J Pharm Pharmacol; 2009 Mar 28; 61(3):339-45. PubMed ID: 19222906
    [Abstract] [Full Text] [Related]

  • 18. Pharmacokinetic, distribution, metabolism, and excretion of (Z)-2-amino-1,5-dihydro-1-methyl-5-[4-(mesyl)benzylidene]-4H-imidazol-4-one mesilate (ZLJ-601) in Sprague-Dawley rats.
    Zhang L, Li N, Lai Y, Zhang Y, Chen X, Chen L, Ji H, Li C.
    Pharmacology; 2012 Mar 28; 89(3-4):192-200. PubMed ID: 22456195
    [Abstract] [Full Text] [Related]

  • 19. Effects of tanshinone I isolated from Salvia miltiorrhiza bunge on arachidonic acid metabolism and in vivo inflammatory responses.
    Kim SY, Moon TC, Chang HW, Son KH, Kang SS, Kim HP.
    Phytother Res; 2002 Nov 28; 16(7):616-20. PubMed ID: 12410540
    [Abstract] [Full Text] [Related]

  • 20. Licofelone, an inhibitor of cyclooxygenase and 5-lipoxygenase, specifically inhibits cyclooxygenase-1-dependent platelet activation.
    Rotondo S, Krauze-Brzósko K, Manarini S, Evangelista V, Cerletti C.
    Eur J Pharmacol; 2004 Mar 19; 488(1-3):79-83. PubMed ID: 15044038
    [Abstract] [Full Text] [Related]

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