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Journal Abstract Search

322 related items for PubMed ID: 19251093

  • 1. Inhibition of 4E-BP1 sensitizes U87 glioblastoma xenograft tumors to irradiation by decreasing hypoxia tolerance.
    Dubois L, Magagnin MG, Cleven AH, Weppler SA, Grenacher B, Landuyt W, Lieuwes N, Lambin P, Gorr TA, Koritzinsky M, Wouters BG.
    Int J Radiat Oncol Biol Phys; 2009 Mar 15; 73(4):1219-27. PubMed ID: 19251093
    [Abstract] [Full Text] [Related]

  • 2. Adenovirus-mediated eukaryotic initiation factor 4E binding protein-1 in combination with rapamycin inhibits tumor growth of pancreatic ductal adenocarcinoma in vivo.
    Mishra R, Miyamoto M, Yoshioka T, Ishikawa K, Matsumura Y, Shoji Y, Ichinokawa K, Itoh T, Shichinohe T, Hirano S, Kondo S.
    Int J Oncol; 2009 May 15; 34(5):1231-40. PubMed ID: 19360336
    [Abstract] [Full Text] [Related]

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  • 4. Deregulation of cap-dependent mRNA translation increases tumour radiosensitivity through reduction of the hypoxic fraction.
    Rouschop KM, Dubois L, Schaaf MB, van den Beucken T, Lieuwes N, Keulers TG, Savelkouls KG, Bussink J, van der Kogel AJ, Koritzinsky M, Wouters BG.
    Radiother Oncol; 2011 Jun 15; 99(3):385-91. PubMed ID: 21665307
    [Abstract] [Full Text] [Related]

  • 5. Phenethyl isothiocyanate, a cancer chemopreventive constituent of cruciferous vegetables, inhibits cap-dependent translation by regulating the level and phosphorylation of 4E-BP1.
    Hu J, Straub J, Xiao D, Singh SV, Yang HS, Sonenberg N, Vatsyayan J.
    Cancer Res; 2007 Apr 15; 67(8):3569-73. PubMed ID: 17440067
    [Abstract] [Full Text] [Related]

  • 6. Biochemical correlates of mTOR inhibition by the rapamycin ester CCI-779 and tumor growth inhibition.
    Dudkin L, Dilling MB, Cheshire PJ, Harwood FC, Hollingshead M, Arbuck SG, Travis R, Sausville EA, Houghton PJ.
    Clin Cancer Res; 2001 Jun 15; 7(6):1758-64. PubMed ID: 11410517
    [Abstract] [Full Text] [Related]

  • 7. The effect of p-4E-BP1 and p-eIF4E on cell proliferation in a breast cancer model.
    Pons B, Peg V, Vázquez-Sánchez MA, López-Vicente L, Argelaguet E, Coch L, Martínez A, Hernández-Losa J, Armengol G, Ramon Y Cajal S.
    Int J Oncol; 2011 Nov 15; 39(5):1337-45. PubMed ID: 21750861
    [Abstract] [Full Text] [Related]

  • 8. Phosphorylation of eIF2alpha is required for mRNA translation inhibition and survival during moderate hypoxia.
    Koritzinsky M, Rouschop KM, van den Beucken T, Magagnin MG, Savelkouls K, Lambin P, Wouters BG.
    Radiother Oncol; 2007 Jun 15; 83(3):353-61. PubMed ID: 17531337
    [Abstract] [Full Text] [Related]

  • 9. Regulation of the phosphorylation and integrity of protein synthesis initiation factor eIF4GI and the translational repressor 4E-BP1 by p53.
    Constantinou C, Clemens MJ.
    Oncogene; 2005 Jul 14; 24(30):4839-50. PubMed ID: 15897901
    [Abstract] [Full Text] [Related]

  • 10. Suppression of translation during in vitro maturation of pig oocytes despite enhanced formation of cap-binding protein complex eIF4F and 4E-BP1 hyperphosphorylation.
    Ellederova Z, Kovarova H, Melo-Sterza F, Livingstone M, Tomek W, Kubelka M.
    Mol Reprod Dev; 2006 Jan 14; 73(1):68-76. PubMed ID: 16211600
    [Abstract] [Full Text] [Related]

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  • 12. Tumor-specific RNAi targeting eIF4E suppresses tumor growth, induces apoptosis and enhances cisplatin cytotoxicity in human breast carcinoma cells.
    Dong K, Wang R, Wang X, Lin F, Shen JJ, Gao P, Zhang HZ.
    Breast Cancer Res Treat; 2009 Feb 14; 113(3):443-56. PubMed ID: 18327707
    [Abstract] [Full Text] [Related]

  • 13. Paclitaxel induces the phosphorylation of the eukaryotic translation initiation factor 4E-binding protein 1 through a Cdk1-dependent mechanism.
    Greenberg VL, Zimmer SG.
    Oncogene; 2005 Jul 14; 24(30):4851-60. PubMed ID: 15897904
    [Abstract] [Full Text] [Related]

  • 14. Regulation of human eIF4E by 4E-BP1: binding analysis using surface plasmon resonance.
    Youtani T, Tomoo K, Ishida T, Miyoshi H, Miura K.
    IUBMB Life; 2000 Jan 14; 49(1):27-31. PubMed ID: 10772338
    [Abstract] [Full Text] [Related]

  • 15. The embryonic pregnancy signal oestradiol influences gene expression at the level of translational initiation in porcine endometrial cells.
    Wollenhaupt K, Brüssow KP, Tiemann U, Tomek W.
    Reprod Domest Anim; 2007 Apr 14; 42(2):167-75. PubMed ID: 17348974
    [Abstract] [Full Text] [Related]

  • 16. eIF4E/4E-BP ratio predicts the efficacy of mTOR targeted therapies.
    Alain T, Morita M, Fonseca BD, Yanagiya A, Siddiqui N, Bhat M, Zammit D, Marcus V, Metrakos P, Voyer LA, Gandin V, Liu Y, Topisirovic I, Sonenberg N.
    Cancer Res; 2012 Dec 15; 72(24):6468-76. PubMed ID: 23100465
    [Abstract] [Full Text] [Related]

  • 17. eIF4E activation is commonly elevated in advanced human prostate cancers and significantly related to reduced patient survival.
    Graff JR, Konicek BW, Lynch RL, Dumstorf CA, Dowless MS, McNulty AM, Parsons SH, Brail LH, Colligan BM, Koop JW, Hurst BM, Deddens JA, Neubauer BL, Stancato LF, Carter HW, Douglass LE, Carter JH.
    Cancer Res; 2009 May 01; 69(9):3866-73. PubMed ID: 19383915
    [Abstract] [Full Text] [Related]

  • 18. The mTOR Targets 4E-BP1/2 Restrain Tumor Growth and Promote Hypoxia Tolerance in PTEN-driven Prostate Cancer.
    Ding M, Van der Kwast TH, Vellanki RN, Foltz WD, McKee TD, Sonenberg N, Pandolfi PP, Koritzinsky M, Wouters BG.
    Mol Cancer Res; 2018 Apr 01; 16(4):682-695. PubMed ID: 29453322
    [Abstract] [Full Text] [Related]

  • 19. Nitric oxide mediates NMDA-induced persistent inhibition of protein synthesis through dephosphorylation of eukaryotic initiation factor 4E-binding protein 1 and eukaryotic initiation factor 4G proteolysis.
    Petegnief V, Font-Nieves M, Martín ME, Salinas M, Planas AM.
    Biochem J; 2008 May 01; 411(3):667-77. PubMed ID: 18215131
    [Abstract] [Full Text] [Related]

  • 20. Contribution of HIF-1α in 4E-BP1 gene expression.
    Azar R, Lasfargues C, Bousquet C, Pyronnet S.
    Mol Cancer Res; 2013 Jan 01; 11(1):54-61. PubMed ID: 23175522
    [Abstract] [Full Text] [Related]

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