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304 related items for PubMed ID: 19251822

  • 1. Assessing the metabolic competence of sandwich-cultured mouse primary hepatocytes.
    Mathijs K, Kienhuis AS, Brauers KJ, Jennen DG, Lahoz A, Kleinjans JC, van Delft JH.
    Drug Metab Dispos; 2009 Jun; 37(6):1305-11. PubMed ID: 19251822
    [Abstract] [Full Text] [Related]

  • 2. A sandwich-cultured rat hepatocyte system with increased metabolic competence evaluated by gene expression profiling.
    Kienhuis AS, Wortelboer HM, Maas WJ, van Herwijnen M, Kleinjans JC, van Delft JH, Stierum RH.
    Toxicol In Vitro; 2007 Aug; 21(5):892-901. PubMed ID: 17336492
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  • 3. Effects of cell culture conditions on primary rat hepatocytes-cell morphology and differential gene expression.
    Tuschl G, Mueller SO.
    Toxicology; 2006 Feb 01; 218(2-3):205-15. PubMed ID: 16337326
    [Abstract] [Full Text] [Related]

  • 4. The suitability of hepatocyte culture models to study various aspects of drug metabolism.
    Nussler AK, Wang A, Neuhaus P, Fischer J, Yuan J, Liu L, Zeilinger K, Gerlach J, Arnold PJ, Albrecht W.
    ALTEX; 2001 Feb 01; 18(2):91-101. PubMed ID: 11378681
    [Abstract] [Full Text] [Related]

  • 5. Comparison of coumarin-induced toxicity between sandwich-cultured primary rat hepatocytes and rats in vivo: a toxicogenomics approach.
    Kienhuis AS, Wortelboer HM, Hoflack JC, Moonen EJ, Kleinjans JC, van Ommen B, van Delft JH, Stierum RH.
    Drug Metab Dispos; 2006 Dec 01; 34(12):2083-90. PubMed ID: 16963487
    [Abstract] [Full Text] [Related]

  • 6. Xenobiotic metabolism and toxicity in primary monolayer cultures of hepatocytes.
    Holme JA.
    NIPH Ann; 1985 Dec 01; 8(2):49-63. PubMed ID: 3908998
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  • 7. Serum-free collagen sandwich cultures of adult rat hepatocytes maintain liver-like properties long term: a valuable model for in vitro toxicity and drug-drug interaction studies.
    Tuschl G, Hrach J, Walter Y, Hewitt PG, Mueller SO.
    Chem Biol Interact; 2009 Sep 14; 181(1):124-37. PubMed ID: 19482013
    [Abstract] [Full Text] [Related]

  • 8. Primary culture of rat hepatocytes in 96-well plates: effects of extracellular matrix configuration on cytochrome P450 enzyme activity and inducibility, and its application in in vitro cytotoxicity screening.
    Mingoia RT, Nabb DL, Yang CH, Han X.
    Toxicol In Vitro; 2007 Feb 14; 21(1):165-73. PubMed ID: 17141466
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  • 9. Network analysis of primary hepatocyte dedifferentiation using a shotgun proteomics approach.
    Rowe C, Goldring CE, Kitteringham NR, Jenkins RE, Lane BS, Sanderson C, Elliott V, Platt V, Metcalfe P, Park BK.
    J Proteome Res; 2010 May 07; 9(5):2658-68. PubMed ID: 20373825
    [Abstract] [Full Text] [Related]

  • 10. Gene expression in two hepatic cell lines, cultured primary hepatocytes, and liver slices compared to the in vivo liver gene expression in rats: possible implications for toxicogenomics use of in vitro systems.
    Boess F, Kamber M, Romer S, Gasser R, Muller D, Albertini S, Suter L.
    Toxicol Sci; 2003 Jun 07; 73(2):386-402. PubMed ID: 12657743
    [Abstract] [Full Text] [Related]

  • 11. Influence of culture time on the expression of drug-metabolizing enzymes in primary human hepatocytes and hepatoma cell line HepG2.
    Wilkening S, Bader A.
    J Biochem Mol Toxicol; 2003 Jun 07; 17(4):207-13. PubMed ID: 12898644
    [Abstract] [Full Text] [Related]

  • 12. Interspecies difference in liver-specific functions and biotransformation of testosterone of primary rat, porcine and human hepatocyte in an organotypical sandwich culture.
    Langsch A, Giri S, Acikgöz A, Jasmund I, Frericks B, Bader A.
    Toxicol Lett; 2009 Aug 10; 188(3):173-9. PubMed ID: 19428196
    [Abstract] [Full Text] [Related]

  • 13. Characterization of enzymes responsible for biotransformation of the new antileukotrienic drug quinlukast in rat liver microsomes and in primary cultures of rat hepatocytes.
    Szotáková B, Skálová L, Baliharová V, Dvorscáková M, Storkánová L, Sispera L, Wsól V.
    J Pharm Pharmacol; 2004 Feb 10; 56(2):205-12. PubMed ID: 15005879
    [Abstract] [Full Text] [Related]

  • 14. Genomics and proteomics analysis of cultured primary rat hepatocytes.
    Beigel J, Fella K, Kramer PJ, Kroeger M, Hewitt P.
    Toxicol In Vitro; 2008 Feb 10; 22(1):171-81. PubMed ID: 17768030
    [Abstract] [Full Text] [Related]

  • 15. Absolute quantification and differential expression of drug transporters, cytochrome P450 enzymes, and UDP-glucuronosyltransferases in cultured primary human hepatocytes.
    Schaefer O, Ohtsuki S, Kawakami H, Inoue T, Liehner S, Saito A, Sakamoto A, Ishiguro N, Matsumaru T, Terasaki T, Ebner T.
    Drug Metab Dispos; 2012 Jan 10; 40(1):93-103. PubMed ID: 21979928
    [Abstract] [Full Text] [Related]

  • 16. Enhanced oxygen delivery reverses anaerobic metabolic states in prolonged sandwich rat hepatocyte culture.
    Bader A, Frühauf N, Tiedge M, Drinkgern M, De Bartolo L, Borlak JT, Steinhoff G, Haverich A.
    Exp Cell Res; 1999 Jan 10; 246(1):221-32. PubMed ID: 9882531
    [Abstract] [Full Text] [Related]

  • 17. Dose- and time-dependent effects of phenobarbital on gene expression profiling in human hepatoma HepaRG cells.
    Lambert CB, Spire C, Claude N, Guillouzo A.
    Toxicol Appl Pharmacol; 2009 Feb 01; 234(3):345-60. PubMed ID: 19084549
    [Abstract] [Full Text] [Related]

  • 18. Cryopreservation of rat and mouse hepatocytes. II. Assessment of metabolic capacity using testosterone metabolism.
    Swales NJ, Johnson T, Caldwell J.
    Drug Metab Dispos; 1996 Nov 01; 24(11):1224-30. PubMed ID: 8937857
    [Abstract] [Full Text] [Related]

  • 19. Collagen gel immobilization: a useful cell culture technique for long-term metabolic studies on human hepatocytes.
    Koebe HG, Pahernik S, Eyer P, Schildberg FW.
    Xenobiotica; 1994 Feb 01; 24(2):95-107. PubMed ID: 8017092
    [Abstract] [Full Text] [Related]

  • 20. Gene expression and functional analyses of primary rat hepatocytes on nanofiber matrices.
    Brophy CM, Luebke-Wheeler JL, Amiot BP, Remmel RP, Rinaldo P, Nyberg SL.
    Cells Tissues Organs; 2010 Feb 01; 191(2):129-40. PubMed ID: 19494481
    [Abstract] [Full Text] [Related]

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