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Journal Abstract Search

129 related items for PubMed ID: 19256501

  • 1. Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Wan H, Ahman M, Holmén AG.
    J Med Chem; 2009 Mar 26; 52(6):1693-700. PubMed ID: 19256501
    [Abstract] [Full Text] [Related]

  • 2. How well do lipophilicity parameters, MEEKC microemulsion capacity factor, and plasma protein binding predict CNS tissue binding?
    Zamek-Gliszczynski MJ, Sprague KE, Espada A, Raub TJ, Morton SM, Manro JR, Molina-Martin M.
    J Pharm Sci; 2012 May 26; 101(5):1932-40. PubMed ID: 22344827
    [Abstract] [Full Text] [Related]

  • 3. Microemulsion electrokinetic chromatography hyphenated to atmospheric pressure photoionization mass spectrometry.
    Schappler J, Guillarme D, Rudaz S, Veuthey JL.
    Electrophoresis; 2008 Jan 26; 29(1):11-9. PubMed ID: 18161697
    [Abstract] [Full Text] [Related]

  • 4. Addressing central nervous system (CNS) penetration in drug discovery: basics and implications of the evolving new concept.
    Reichel A.
    Chem Biodivers; 2009 Nov 26; 6(11):2030-49. PubMed ID: 19937839
    [Abstract] [Full Text] [Related]

  • 5. High-throughput screening of drug-brain tissue binding and in silico prediction for assessment of central nervous system drug delivery.
    Wan H, Rehngren M, Giordanetto F, Bergström F, Tunek A.
    J Med Chem; 2007 Sep 20; 50(19):4606-15. PubMed ID: 17725338
    [Abstract] [Full Text] [Related]

  • 6. Predicting blood-brain barrier penetration of drugs by microemulsion liquid chromatography with corrected retention factor.
    Liu J, Sun J, Sui X, Wang Y, Hou Y, He Z.
    J Chromatogr A; 2008 Jul 11; 1198-1199():164-72. PubMed ID: 18541248
    [Abstract] [Full Text] [Related]

  • 7. High-throughput screening of protein binding by equilibrium dialysis combined with liquid chromatography and mass spectrometry.
    Wan H, Rehngren M.
    J Chromatogr A; 2006 Jan 13; 1102(1-2):125-34. PubMed ID: 16266710
    [Abstract] [Full Text] [Related]

  • 8. Determination of octanol-water partition coefficients for carbonate esters and other small organic molecules by microemulsion electrokinetic chromatography.
    Østergaard J, Hansen SH, Larsen C, Schou C, Heegaard NH.
    Electrophoresis; 2003 Mar 13; 24(6):1038-46. PubMed ID: 12658693
    [Abstract] [Full Text] [Related]

  • 9. A quantitative structure-activity approach for lipophilicity estimation of antitumor complexes of different metals using microemulsion electrokinetic chromatography.
    Foteeva LS, Trofimov DA, Kuznetsova OV, Kowol CR, Arion VB, Keppler BK, Timerbaev AR.
    J Pharm Biomed Anal; 2011 Jun 01; 55(3):409-13. PubMed ID: 21382684
    [Abstract] [Full Text] [Related]

  • 10. Anion-selective exhaustive injection-sweeping microemulsion electrokinetic chromatography.
    Huang HY, Lien WC, Huang IY.
    Electrophoresis; 2006 Aug 01; 27(16):3202-9. PubMed ID: 16850505
    [Abstract] [Full Text] [Related]

  • 11. Relationship between exposure and nonspecific binding of thirty-three central nervous system drugs in mice.
    Maurer TS, Debartolo DB, Tess DA, Scott DO.
    Drug Metab Dispos; 2005 Jan 01; 33(1):175-81. PubMed ID: 15502010
    [Abstract] [Full Text] [Related]

  • 12. Principles and applicability of CSF sampling for the assessment of CNS drug delivery and pharmacodynamics.
    Shen DD, Artru AA, Adkison KK.
    Adv Drug Deliv Rev; 2004 Oct 14; 56(12):1825-57. PubMed ID: 15381336
    [Abstract] [Full Text] [Related]

  • 13. Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Longhi R, Corbioli S, Fontana S, Vinco F, Braggio S, Helmdach L, Schiller J, Boriss H.
    Drug Metab Dispos; 2011 Feb 14; 39(2):312-21. PubMed ID: 21071520
    [Abstract] [Full Text] [Related]

  • 14. Improvement of microemulsion electrokinetic chromatography for measuring octanol-water partition coefficients.
    Xia Z, Jiang X, Mu X, Chen H.
    Electrophoresis; 2008 Feb 14; 29(4):835-42. PubMed ID: 18203250
    [Abstract] [Full Text] [Related]

  • 15. High throughput screening of physicochemical properties and in vitro ADME profiling in drug discovery.
    Wan H, Holmén AG.
    Comb Chem High Throughput Screen; 2009 Mar 14; 12(3):315-29. PubMed ID: 19275537
    [Abstract] [Full Text] [Related]

  • 16. Assessing brain free fraction in early drug discovery.
    Read KD, Braggio S.
    Expert Opin Drug Metab Toxicol; 2010 Mar 14; 6(3):337-44. PubMed ID: 20102287
    [Abstract] [Full Text] [Related]

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  • 20. Potential of biopartitioning micellar chromatography as an in vitro technique for predicting drug penetration across the blood-brain barrier.
    Escuder-Gilabert L, Molero-Monfort M, Villanueva-Camañas RM, Sagrado S, Medina-Hernández MJ.
    J Chromatogr B Analyt Technol Biomed Life Sci; 2004 Aug 05; 807(2):193-201. PubMed ID: 15203029
    [Abstract] [Full Text] [Related]

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