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2867 related items for PubMed ID: 19258520

  • 1. Resistance to mitogen-activated protein kinase kinase (MEK) inhibitors correlates with up-regulation of the MEK/extracellular signal-regulated kinase pathway in hepatocellular carcinoma cells.
    Yip-Schneider MT, Klein PJ, Wentz SC, Zeni A, Menze A, Schmidt CM.
    J Pharmacol Exp Ther; 2009 Jun; 329(3):1063-70. PubMed ID: 19258520
    [Abstract] [Full Text] [Related]

  • 2. The effect of doxorubicin on MEK-ERK signaling predicts its efficacy in HCC.
    Choi J, Yip-Schneider M, Albertin F, Wiesenauer C, Wang Y, Schmidt CM.
    J Surg Res; 2008 Dec; 150(2):219-26. PubMed ID: 18468633
    [Abstract] [Full Text] [Related]

  • 3. Differential sensitivity of chemoresistant neuroblastoma subtypes to MAPK-targeted treatment correlates with ERK, p53 expression, and signaling response to U0126.
    Eppstein AC, Sandoval JA, Klein PJ, Woodruff HA, Grosfeld JL, Hickey RJ, Malkas LH, Schmidt CM.
    J Pediatr Surg; 2006 Jan; 41(1):252-9. PubMed ID: 16410143
    [Abstract] [Full Text] [Related]

  • 4. Activation of the RAF/mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase pathway mediates apoptosis induced by chelerythrine in osteosarcoma.
    Yang R, Piperdi S, Gorlick R.
    Clin Cancer Res; 2008 Oct 15; 14(20):6396-404. PubMed ID: 18927278
    [Abstract] [Full Text] [Related]

  • 5. Role of RAF/MEK/ERK pathway, p-STAT-3 and Mcl-1 in sorafenib activity in human pancreatic cancer cell lines.
    Ulivi P, Arienti C, Amadori D, Fabbri F, Carloni S, Tesei A, Vannini I, Silvestrini R, Zoli W.
    J Cell Physiol; 2009 Jul 15; 220(1):214-21. PubMed ID: 19288493
    [Abstract] [Full Text] [Related]

  • 6. p21WAF1 expression induced by MEK/ERK pathway activation or inhibition correlates with growth arrest, myogenic differentiation and onco-phenotype reversal in rhabdomyosarcoma cells.
    Ciccarelli C, Marampon F, Scoglio A, Mauro A, Giacinti C, De Cesaris P, Zani BM.
    Mol Cancer; 2005 Dec 13; 4():41. PubMed ID: 16351709
    [Abstract] [Full Text] [Related]

  • 7. Phosphorylation regulates Myc expression via prolonged activation of the mitogen-activated protein kinase pathway.
    Wang Z, Ge L, Wang M, Carr BI.
    J Cell Physiol; 2006 Jul 13; 208(1):133-40. PubMed ID: 16596619
    [Abstract] [Full Text] [Related]

  • 8. Raf-1 kinase activation is uncoupled from downstream MEK/ERK pathway in cells treated with Src tyrosine kinase inhibitor PP2.
    Lee M.
    Biochem Biophys Res Commun; 2006 Nov 17; 350(2):450-6. PubMed ID: 17010316
    [Abstract] [Full Text] [Related]

  • 9. Down-regulation of c-Myc following MEK/ERK inhibition halts the expression of malignant phenotype in rhabdomyosarcoma and in non muscle-derived human tumors.
    Marampon F, Ciccarelli C, Zani BM.
    Mol Cancer; 2006 Aug 09; 5():31. PubMed ID: 16899113
    [Abstract] [Full Text] [Related]

  • 10. Overactivation of the MEK/ERK pathway in liver tumor cells confers resistance to TGF-{beta}-induced cell death through impairing up-regulation of the NADPH oxidase NOX4.
    Caja L, Sancho P, Bertran E, Iglesias-Serret D, Gil J, Fabregat I.
    Cancer Res; 2009 Oct 01; 69(19):7595-602. PubMed ID: 19773433
    [Abstract] [Full Text] [Related]

  • 11. MEK/ERK-dependent uPAR expression is required for motility via phosphorylation of P70S6K in human hepatocarcinoma cells.
    Bessard A, Frémin C, Ezan F, Coutant A, Baffet G.
    J Cell Physiol; 2007 Aug 01; 212(2):526-36. PubMed ID: 17427199
    [Abstract] [Full Text] [Related]

  • 12. Changes in androgen receptor nongenotropic signaling correlate with transition of LNCaP cells to androgen independence.
    Unni E, Sun S, Nan B, McPhaul MJ, Cheskis B, Mancini MA, Marcelli M.
    Cancer Res; 2004 Oct 01; 64(19):7156-68. PubMed ID: 15466214
    [Abstract] [Full Text] [Related]

  • 13. [The role of extracellular signal-regulated kinase/mitogen-activated protein kinase pathway in multidrug resistance of hepatocellular carcinoma].
    Zhu H, Chen XP, Luo SF, Guan J, Zhang WG, Zhang BX, Mao CP.
    Zhonghua Wai Ke Za Zhi; 2007 Jul 01; 45(13):917-20. PubMed ID: 17953842
    [Abstract] [Full Text] [Related]

  • 14. Down-regulation of mcl-1 by small interfering RNA sensitizes resistant melanoma cells to fas-mediated apoptosis.
    Chetoui N, Sylla K, Gagnon-Houde JV, Alcaide-Loridan C, Charron D, Al-Daccak R, Aoudjit F.
    Mol Cancer Res; 2008 Jan 01; 6(1):42-52. PubMed ID: 18234961
    [Abstract] [Full Text] [Related]

  • 15. Significant anti-proliferation of human endometrial cancer cells by combined treatment with a selective COX-2 inhibitor NS398 and specific MEK inhibitor U0126.
    Gao J, Niwa K, Takemura M, Sun W, Onogi K, Wu Y, Seishima M, Mori H, Tamaya T.
    Int J Oncol; 2005 Mar 01; 26(3):737-44. PubMed ID: 15703831
    [Abstract] [Full Text] [Related]

  • 16. XAF1 mediates apoptosis through an extracellular signal-regulated kinase pathway in colon cancer.
    Yu LF, Wang J, Zou B, Lin MC, Wu YL, Xia HH, Sun YW, Gu Q, He H, Lam SK, Kung HF, Wong BC.
    Cancer; 2007 May 15; 109(10):1996-2003. PubMed ID: 17385215
    [Abstract] [Full Text] [Related]

  • 17. Asiatic acid, a triterpene, induces apoptosis and cell cycle arrest through activation of extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways in human breast cancer cells.
    Hsu YL, Kuo PL, Lin LT, Lin CC.
    J Pharmacol Exp Ther; 2005 Apr 15; 313(1):333-44. PubMed ID: 15626723
    [Abstract] [Full Text] [Related]

  • 18. Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5.
    Liu L, Cao Y, Chen C, Zhang X, McNabola A, Wilkie D, Wilhelm S, Lynch M, Carter C.
    Cancer Res; 2006 Dec 15; 66(24):11851-8. PubMed ID: 17178882
    [Abstract] [Full Text] [Related]

  • 19. Oncogenic tyrosine kinase NPM/ALK induces activation of the MEK/ERK signaling pathway independently of c-Raf.
    Marzec M, Kasprzycka M, Liu X, Raghunath PN, Wlodarski P, Wasik MA.
    Oncogene; 2007 Feb 08; 26(6):813-21. PubMed ID: 16909118
    [Abstract] [Full Text] [Related]

  • 20. Neurotensin stimulates protein kinase C-dependent mitogenic signaling in human pancreatic carcinoma cell line PANC-1.
    Guha S, Lunn JA, Santiskulvong C, Rozengurt E.
    Cancer Res; 2003 May 15; 63(10):2379-87. PubMed ID: 12750255
    [Abstract] [Full Text] [Related]

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