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Journal Abstract Search

212 related items for PubMed ID: 19272774

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  • 3. Microwave-assisted synthesis of potent PDE7 inhibitors containing a thienopyrimidin-4-amine scaffold.
    Sánchez AI, Meneses R, Mínguez JM, Núñez A, Castillo RR, Filace F, Burgos C, Vaquero JJ, Álvarez-Builla J, Cortés-Cabrera A, Gago F, Terricabras E, Segarra V.
    Org Biomol Chem; 2014 Jun 28; 12(24):4233-42. PubMed ID: 24838636
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  • 4. Discovery and SAR study of 2-(4-pyridylamino)thieno[3,2-d]pyrimidin-4(3H)-ones as soluble and highly potent PDE7 inhibitors.
    Endo Y, Kawai K, Asano T, Amano S, Asanuma Y, Sawada K, Ogura K, Nagata N, Ueo N, Takahashi N, Sonoda Y, Kamei N.
    Bioorg Med Chem Lett; 2015 Feb 01; 25(3):649-53. PubMed ID: 25529739
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  • 6. Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 1: design, synthesis and structure-activity relationship studies.
    Vergne F, Bernardelli P, Lorthiois E, Pham N, Proust E, Oliveira C, Mafroud AK, Royer F, Wrigglesworth R, Schellhaas J, Barvian M, Moreau F, Idrissi M, Tertre A, Bertin B, Coupe M, Berna P, Soulard P.
    Bioorg Med Chem Lett; 2004 Sep 20; 14(18):4607-13. PubMed ID: 15324874
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  • 7. Identification of purine inhibitors of phosphodiesterase 7 (PDE7).
    Pitts WJ, Vaccaro W, Huynh T, Leftheris K, Roberge JY, Barbosa J, Guo J, Brown B, Watson A, Donaldson K, Starling GC, Kiener PA, Poss MA, Dodd JH, Barrish JC.
    Bioorg Med Chem Lett; 2004 Jun 07; 14(11):2955-8. PubMed ID: 15125967
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  • 9. Effect of phosphodiesterase 7 inhibitor ASB16165 on development and function of cytotoxic T lymphocyte.
    Kadoshima-Yamaoka K, Murakawa M, Goto M, Tanaka Y, Inoue H, Murafuji H, Hayashi Y, Nagahira K, Miura K, Nakatsuka T, Chamoto K, Fukuda Y, Nishimura T.
    Int Immunopharmacol; 2009 Jan 07; 9(1):97-102. PubMed ID: 18992850
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  • 10. Synthesis and structure-activity relationship studies of dihydronaphthyridinediones as a novel structural class of potent and selective PDE7 inhibitors.
    Gewald R, Rueger C, Grunwald C, Egerland U, Hoefgen N.
    Bioorg Med Chem Lett; 2011 Nov 15; 21(22):6652-6. PubMed ID: 21983442
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  • 11. Unraveling phosphodiesterase surfaces. Identification of phosphodiesterase 7 allosteric modulation cavities.
    Redondo M, Soteras I, Brea J, González-García A, Cadavid MI, Loza MI, Martinez A, Gil C, Campillo NE.
    Eur J Med Chem; 2013 Nov 15; 70():781-8. PubMed ID: 24239625
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  • 12. Isothiazole and isoxazole fused pyrimidones as PDE7 inhibitors: SAR and pharmacokinetic evaluation.
    Banerjee A, Yadav PS, Bajpai M, Sangana RR, Gullapalli S, Gudi GS, Gharat LA.
    Bioorg Med Chem Lett; 2012 May 01; 22(9):3223-8. PubMed ID: 22487174
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  • 14. Cloning, stable expression of human phosphodiesterase 7A and development of an assay for screening of PDE7 selective inhibitors.
    Malik R, Bora RS, Gupta D, Sharma P, Arya R, Chaudhary S, Saini KS.
    Appl Microbiol Biotechnol; 2008 Jan 01; 77(5):1167-73. PubMed ID: 17952431
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  • 16. Synthesis and evaluation of quinazoline derivatives as phosphodiesterase 7 inhibitors.
    Sánchez AI, Martínez-Barrasa V, Burgos C, Vaquero JJ, Alvarez-Builla J, Terricabras E, Segarra V.
    Bioorg Med Chem; 2013 Apr 15; 21(8):2370-2378. PubMed ID: 23454131
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  • 17. Role of Phosphodiesterase 7 (PDE7) in T Cell Activity. Effects of Selective PDE7 Inhibitors and Dual PDE4/7 Inhibitors on T Cell Functions.
    Szczypka M.
    Int J Mol Sci; 2020 Aug 25; 21(17):. PubMed ID: 32854348
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  • 18. Discovery of 2-(cyclopentylamino)thieno[3,2-d]pyrimidin-4(3H)-one derivatives as a new series of potent phosphodiesterase 7 inhibitors.
    Kawai K, Endo Y, Asano T, Amano S, Sawada K, Ueo N, Takahashi N, Sonoda Y, Nagai M, Kamei N, Nagata N.
    J Med Chem; 2014 Dec 11; 57(23):9844-54. PubMed ID: 25383422
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  • 19. New methods for the discovery and synthesis of PDE7 inhibitors as new drugs for neurological and inflammatory disorders.
    Safavi M, Baeeri M, Abdollahi M.
    Expert Opin Drug Discov; 2013 Jun 11; 8(6):733-51. PubMed ID: 23570245
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  • 20. Modulation of cAMP-specific PDE without emetogenic activity: new sulfide-like PDE7 inhibitors.
    García AM, Brea J, Morales-García JA, Perez DI, González A, Alonso-Gil S, Gracia-Rubio I, Ros-Simó C, Conde S, Cadavid MI, Loza MI, Perez-Castillo A, Valverde O, Martinez A, Gil C.
    J Med Chem; 2014 Oct 23; 57(20):8590-607. PubMed ID: 25264825
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