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Journal Abstract Search

306 related items for PubMed ID: 19282188

  • 1. Discovery and structure-activity relationships of (2-(arylthio)benzylideneamino)guanidines as a novel series of potent apoptosis inducers.
    Zhang HZ, Crogan-Grundy C, May C, Drewe J, Tseng B, Cai SX.
    Bioorg Med Chem; 2009 Apr 01; 17(7):2852-8. PubMed ID: 19282188
    [Abstract] [Full Text] [Related]

  • 2. Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. Part 1: Structure-activity relationships of the 1- and 3-positions.
    Kemnitzer W, Kuemmerle J, Jiang S, Zhang HZ, Sirisoma N, Kasibhatla S, Crogan-Grundy C, Tseng B, Drewe J, Cai SX.
    Bioorg Med Chem Lett; 2008 Dec 01; 18(23):6259-64. PubMed ID: 18952423
    [Abstract] [Full Text] [Related]

  • 3. Discovery of 4-anilino-N-methylthieno[3,2-d]pyrimidines and 4-anilino-N-methylthieno[2,3-d]pyrimidines as potent apoptosis inducers.
    Kemnitzer W, Sirisoma N, May C, Tseng B, Drewe J, Cai SX.
    Bioorg Med Chem Lett; 2009 Jul 01; 19(13):3536-40. PubMed ID: 19464890
    [Abstract] [Full Text] [Related]

  • 4. Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. 4. Structure-activity relationships of N-alkyl substituted pyrrole fused at the 7,8-positions.
    Kemnitzer W, Drewe J, Jiang S, Zhang H, Crogan-Grundy C, Labreque D, Bubenick M, Attardo G, Denis R, Lamothe S, Gourdeau H, Tseng B, Kasibhatla S, Cai SX.
    J Med Chem; 2008 Feb 14; 51(3):417-23. PubMed ID: 18197614
    [Abstract] [Full Text] [Related]

  • 5. Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 1. Structure-activity relationships of the 4-aryl group.
    Kemnitzer W, Drewe J, Jiang S, Zhang H, Wang Y, Zhao J, Jia S, Herich J, Labreque D, Storer R, Meerovitch K, Bouffard D, Rej R, Denis R, Blais C, Lamothe S, Attardo G, Gourdeau H, Tseng B, Kasibhatla S, Cai SX.
    J Med Chem; 2004 Dec 02; 47(25):6299-310. PubMed ID: 15566300
    [Abstract] [Full Text] [Related]

  • 6. Discovery of substituted N-phenyl nicotinamides as potent inducers of apoptosis using a cell- and caspase-based high throughput screening assay.
    Cai SX, Nguyen B, Jia S, Herich J, Guastella J, Reddy S, Tseng B, Drewe J, Kasibhatla S.
    J Med Chem; 2003 Jun 05; 46(12):2474-81. PubMed ID: 12773051
    [Abstract] [Full Text] [Related]

  • 7. Discovery of 5-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-7-phenyl-(E)-2,3,6,7-tetrahydro-1,4-thiazepines as a new series of apoptosis inducers using a cell- and caspase-based HTS assay.
    Drewe J, Kasibhatla S, Tseng B, Shelton E, Sperandio D, Yee RM, Litvak J, Sendzik M, Spencer JR, Cai SX.
    Bioorg Med Chem Lett; 2007 Sep 01; 17(17):4987-90. PubMed ID: 17562361
    [Abstract] [Full Text] [Related]

  • 8. Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2: Structure-activity relationships of the 4-, 5-, 6-, 7- and 8-positions.
    Kemnitzer W, Kuemmerle J, Jiang S, Sirisoma N, Kasibhatla S, Crogan-Grundy C, Tseng B, Drewe J, Cai SX.
    Bioorg Med Chem Lett; 2009 Jul 01; 19(13):3481-4. PubMed ID: 19467598
    [Abstract] [Full Text] [Related]

  • 9. Discovery and structure-activity relationship of N-phenyl-1H-pyrazolo[3,4-b]quinolin-4-amines as a new series of potent apoptosis inducers.
    Zhang HZ, Claassen G, Crogran-Grundy C, Tseng B, Drewe J, Cai SX.
    Bioorg Med Chem; 2008 Jan 01; 16(1):222-31. PubMed ID: 17950608
    [Abstract] [Full Text] [Related]

  • 10. Discovery of substituted 4-anilino-2-(2-pyridyl)pyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. Part 1: structure-activity relationships of the 4-anilino group.
    Sirisoma N, Kasibhatla S, Nguyen B, Pervin A, Wang Y, Claassen G, Tseng B, Drewe J, Cai SX.
    Bioorg Med Chem; 2006 Dec 01; 14(23):7761-73. PubMed ID: 16919962
    [Abstract] [Full Text] [Related]

  • 11. Discovery of N-aryl-9-oxo-9H-fluorene-1-carboxamides as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 1. Structure-activity relationships of the carboxamide group.
    Kemnitzer W, Sirisoma N, Nguyen B, Jiang S, Kasibhatla S, Crogan-Grundy C, Tseng B, Drewe J, Cai SX.
    Bioorg Med Chem Lett; 2009 Jun 01; 19(11):3045-9. PubMed ID: 19394823
    [Abstract] [Full Text] [Related]

  • 12. 4- and 5-aroylindoles as novel classes of potent antitubulin agents.
    Liou JP, Wu CY, Hsieh HP, Chang CY, Chen CM, Kuo CC, Chang JY.
    J Med Chem; 2007 Sep 06; 50(18):4548-52. PubMed ID: 17685504
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and anticancer activity of 2-benzylidene indanones through inhibiting tubulin polymerization.
    Prakasham AP, Saxena AK, Luqman S, Chanda D, Kaur T, Gupta A, Yadav DK, Chanotiya CS, Shanker K, Khan F, Negi AS.
    Bioorg Med Chem; 2012 May 01; 20(9):3049-57. PubMed ID: 22472045
    [Abstract] [Full Text] [Related]

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  • 15. Discovery and SAR of indole-2-carboxylic acid benzylidene-hydrazides as a new series of potent apoptosis inducers using a cell-based HTS assay.
    Zhang HZ, Drewe J, Tseng B, Kasibhatla S, Cai SX.
    Bioorg Med Chem; 2004 Jul 01; 12(13):3649-55. PubMed ID: 15186849
    [Abstract] [Full Text] [Related]

  • 16. Discovery of substituted 4-anilino-2-arylpyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. 2. Structure-activity relationships of the 2-aryl group.
    Sirisoma N, Pervin A, Nguyen B, Crogan-Grundy C, Kasibhatla S, Tseng B, Drewe J, Cai SX.
    Bioorg Med Chem Lett; 2009 Apr 15; 19(8):2305-9. PubMed ID: 19285392
    [Abstract] [Full Text] [Related]

  • 17. Benzoylphenylurea sulfur analogues with potent antitumor activity.
    Hallur G, Jimeno A, Dalrymple S, Zhu T, Jung MK, Hidalgo M, Isaacs JT, Sukumar S, Hamel E, Khan SR.
    J Med Chem; 2006 Apr 06; 49(7):2357-60. PubMed ID: 16570932
    [Abstract] [Full Text] [Related]

  • 18. 9-Benzylidene-naphtho[2,3-b]thiophen-4-ones as novel antimicrotubule agents-synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Zuse A, Schmidt P, Baasner S, Böhm KJ, Müller K, Gerlach M, Günther EG, Unger E, Prinz H.
    J Med Chem; 2006 Dec 28; 49(26):7816-25. PubMed ID: 17181164
    [Abstract] [Full Text] [Related]

  • 19. Discovery of (naphthalen-4-yl)(phenyl)methanones and N-methyl-N-phenylnaphthalen-1-amines as new apoptosis inducers using a cell- and caspase-based HTS assay.
    Jiang S, Crogan-Grundy C, Drewe J, Tseng B, Cai SX.
    Bioorg Med Chem Lett; 2008 Nov 01; 18(21):5725-8. PubMed ID: 18849165
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and structure-activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors.
    Ouyang X, Chen X, Piatnitski EL, Kiselyov AS, He HY, Mao Y, Pattaropong V, Yu Y, Kim KH, Kincaid J, Smith L, Wong WC, Lee SP, Milligan DL, Malikzay A, Fleming J, Gerlak J, Deevi D, Doody JF, Chiang HH, Patel SN, Wang Y, Rolser RL, Kussie P, Labelle M, Tuma MC.
    Bioorg Med Chem Lett; 2005 Dec 01; 15(23):5154-9. PubMed ID: 16198562
    [Abstract] [Full Text] [Related]

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