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268 related items for PubMed ID: 19282454

  • 1. Protein hnRNP A1 and its derivative Up1 unfold quadruplex DNA in the human KRAS promoter: implications for transcription.
    Paramasivam M, Membrino A, Cogoi S, Fukuda H, Nakagama H, Xodo LE.
    Nucleic Acids Res; 2009 May; 37(9):2841-53. PubMed ID: 19282454
    [Abstract] [Full Text] [Related]

  • 2. Structural polymorphism within a regulatory element of the human KRAS promoter: formation of G4-DNA recognized by nuclear proteins.
    Cogoi S, Paramasivam M, Spolaore B, Xodo LE.
    Nucleic Acids Res; 2008 Jun; 36(11):3765-80. PubMed ID: 18490377
    [Abstract] [Full Text] [Related]

  • 3. Protein hnRNPA1 binds to a critical G-rich element of KRAS and unwinds G-quadruplex structures: implications in transcription.
    Xodo L, Paramasivam M, Membrino A, Cogoi S.
    Nucleic Acids Symp Ser (Oxf); 2008 Jun; (52):159-60. PubMed ID: 18776302
    [Abstract] [Full Text] [Related]

  • 4. Interaction of hnRNP A1 with telomere DNA G-quadruplex structures studied at the single molecule level.
    Krüger AC, Raarup MK, Nielsen MM, Kristensen M, Besenbacher F, Kjems J, Birkedal V.
    Eur Biophys J; 2010 Aug; 39(9):1343-50. PubMed ID: 20213319
    [Abstract] [Full Text] [Related]

  • 5. Critical role of hnRNP A1 in activating KRAS transcription in pancreatic cancer cells: A molecular mechanism involving G4 DNA.
    Cogoi S, Rapozzi V, Cauci S, Xodo LE.
    Biochim Biophys Acta Gen Subj; 2017 May; 1861(5 Pt B):1389-1398. PubMed ID: 27888145
    [Abstract] [Full Text] [Related]

  • 6. The mechanism of UP1 binding and unfolding of human telomeric DNA G-quadruplex.
    Ling X, Yao Y, Ding L, Ma J.
    Biochim Biophys Acta Gene Regul Mech; 2023 Dec; 1866(4):194985. PubMed ID: 37717939
    [Abstract] [Full Text] [Related]

  • 7. Primer extension reactions as a tool to uncover folding motifs within complex G-rich sequences: analysis of the human KRAS NHE.
    Paramasivam M, Cogoi S, Xodo LE.
    Chem Commun (Camb); 2011 May 07; 47(17):4965-7. PubMed ID: 21424008
    [Abstract] [Full Text] [Related]

  • 8. Recognition and binding of human telomeric G-quadruplex DNA by unfolding protein 1.
    Hudson JS, Ding L, Le V, Lewis E, Graves D.
    Biochemistry; 2014 May 27; 53(20):3347-56. PubMed ID: 24831962
    [Abstract] [Full Text] [Related]

  • 9. KRAS promoter oligonucleotide with decoy activity dimerizes into a unique topology consisting of two G-quadruplex units.
    Podbevšek P, Plavec J.
    Nucleic Acids Res; 2016 Jan 29; 44(2):917-25. PubMed ID: 26656490
    [Abstract] [Full Text] [Related]

  • 10. G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription.
    Cogoi S, Xodo LE.
    Nucleic Acids Res; 2006 Jan 29; 34(9):2536-49. PubMed ID: 16687659
    [Abstract] [Full Text] [Related]

  • 11. High-resolution three-dimensional NMR structure of the KRAS proto-oncogene promoter reveals key features of a G-quadruplex involved in transcriptional regulation.
    Kerkour A, Marquevielle J, Ivashchenko S, Yatsunyk LA, Mergny JL, Salgado GF.
    J Biol Chem; 2017 May 12; 292(19):8082-8091. PubMed ID: 28330874
    [Abstract] [Full Text] [Related]

  • 12. The KRAS promoter responds to Myc-associated zinc finger and poly(ADP-ribose) polymerase 1 proteins, which recognize a critical quadruplex-forming GA-element.
    Cogoi S, Paramasivam M, Membrino A, Yokoyama KK, Xodo LE.
    J Biol Chem; 2010 Jul 16; 285(29):22003-16. PubMed ID: 20457603
    [Abstract] [Full Text] [Related]

  • 13. Interactions of the A1 heterogeneous nuclear ribonucleoprotein and its proteolytic derivative, UP1, with RNA and DNA: evidence for multiple RNA binding domains and salt-dependent binding mode transitions.
    Nadler SG, Merrill BM, Roberts WJ, Keating KM, Lisbin MJ, Barnett SF, Wilson SH, Williams KR.
    Biochemistry; 1991 Mar 19; 30(11):2968-76. PubMed ID: 1848781
    [Abstract] [Full Text] [Related]

  • 14. Elucidation of the mode of interaction in the UP1-telomerase RNA-telomeric DNA ternary complex which serves to recruit telomerase to telomeric DNA and to enhance the telomerase activity.
    Nagata T, Takada Y, Ono A, Nagata K, Konishi Y, Nukina T, Ono M, Matsugami A, Furukawa A, Fujimoto N, Fukuda H, Nakagama H, Katahira M.
    Nucleic Acids Res; 2008 Dec 19; 36(21):6816-24. PubMed ID: 18953025
    [Abstract] [Full Text] [Related]

  • 15. Structure-based incorporation of 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine into the human telomeric repeat DNA as a probe for UP1 binding and destabilization of G-tetrad structures.
    Myers JC, Moore SA, Shamoo Y.
    J Biol Chem; 2003 Oct 24; 278(43):42300-6. PubMed ID: 12904298
    [Abstract] [Full Text] [Related]

  • 16. MAZ-binding G4-decoy with locked nucleic acid and twisted intercalating nucleic acid modifications suppresses KRAS in pancreatic cancer cells and delays tumor growth in mice.
    Cogoi S, Zorzet S, Rapozzi V, Géci I, Pedersen EB, Xodo LE.
    Nucleic Acids Res; 2013 Apr 24; 41(7):4049-64. PubMed ID: 23471001
    [Abstract] [Full Text] [Related]

  • 17. The regulatory G4 motif of the Kirsten ras (KRAS) gene is sensitive to guanine oxidation: implications on transcription.
    Cogoi S, Ferino A, Miglietta G, Pedersen EB, Xodo LE.
    Nucleic Acids Res; 2018 Jan 25; 46(2):661-676. PubMed ID: 29165690
    [Abstract] [Full Text] [Related]

  • 18. Insight into the Complexity of the i-Motif and G-Quadruplex DNA Structures Formed in the KRAS Promoter and Subsequent Drug-Induced Gene Repression.
    Kaiser CE, Van Ert NA, Agrawal P, Chawla R, Yang D, Hurley LH.
    J Am Chem Soc; 2017 Jun 28; 139(25):8522-8536. PubMed ID: 28570076
    [Abstract] [Full Text] [Related]

  • 19. Thermodynamic and phylogenetic insights into hnRNP A1 recognition of the HIV-1 exon splicing silencer 3 element.
    Rollins C, Levengood JD, Rife BD, Salemi M, Tolbert BS.
    Biochemistry; 2014 Apr 08; 53(13):2172-84. PubMed ID: 24628426
    [Abstract] [Full Text] [Related]

  • 20. The First Crystal Structure of the UP1 Domain of hnRNP A1 Bound to RNA Reveals a New Look for an Old RNA Binding Protein.
    Morgan CE, Meagher JL, Levengood JD, Delproposto J, Rollins C, Stuckey JA, Tolbert BS.
    J Mol Biol; 2015 Oct 09; 427(20):3241-3257. PubMed ID: 26003924
    [Abstract] [Full Text] [Related]

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