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305 related items for PubMed ID: 19285479

  • 1. Role of mitochondria-associated hexokinase II in cancer cell death induced by 3-bromopyruvate.
    Chen Z, Zhang H, Lu W, Huang P.
    Biochim Biophys Acta; 2009 May; 1787(5):553-60. PubMed ID: 19285479
    [Abstract] [Full Text] [Related]

  • 2. Role of reactive oxygen species-mediated mitochondrial dysregulation in 3-bromopyruvate induced cell death in hepatoma cells : ROS-mediated cell death by 3-BrPA.
    Kim JS, Ahn KJ, Kim JA, Kim HM, Lee JD, Lee JM, Kim SJ, Park JH.
    J Bioenerg Biomembr; 2008 Dec; 40(6):607-18. PubMed ID: 19067133
    [Abstract] [Full Text] [Related]

  • 3. The effect of 3-bromopyruvate on human colorectal cancer cells is dependent on glucose concentration but not hexokinase II expression.
    Ho N, Morrison J, Silva A, Coomber BL.
    Biosci Rep; 2016 Jan 06; 36(1):e00299. PubMed ID: 26740252
    [Abstract] [Full Text] [Related]

  • 4. Knockout of VDAC1 in H9c2 Cells Promotes Oxidative Stress-Induced Cell Apoptosis through Decreased Mitochondrial Hexokinase II Binding and Enhanced Glycolytic Stress.
    Yang M, Sun J, Stowe DF, Tajkhorshid E, Kwok WM, Camara AKS.
    Cell Physiol Biochem; 2020 Sep 09; 54(5):853-874. PubMed ID: 32901466
    [Abstract] [Full Text] [Related]

  • 5. Curcumin inhibits aerobic glycolysis and induces mitochondrial-mediated apoptosis through hexokinase II in human colorectal cancer cells in vitro.
    Wang K, Fan H, Chen Q, Ma G, Zhu M, Zhang X, Zhang Y, Yu J.
    Anticancer Drugs; 2015 Jan 09; 26(1):15-24. PubMed ID: 25229889
    [Abstract] [Full Text] [Related]

  • 6. Up-regulation of hexokinaseII in myeloma cells: targeting myeloma cells with 3-bromopyruvate.
    Nakano A, Miki H, Nakamura S, Harada T, Oda A, Amou H, Fujii S, Kagawa K, Takeuchi K, Ozaki S, Matsumoto T, Abe M.
    J Bioenerg Biomembr; 2012 Feb 09; 44(1):31-8. PubMed ID: 22298254
    [Abstract] [Full Text] [Related]

  • 7. Cerulenin-induced apoptosis is mediated by disrupting the interaction between AIF and hexokinase II.
    Jeong NY, Yoo YH.
    Int J Oncol; 2012 Jun 09; 40(6):1949-56. PubMed ID: 22426850
    [Abstract] [Full Text] [Related]

  • 8. 3-Bromopyruvate regulates the status of glycolysis and BCNU sensitivity in human hepatocellular carcinoma cells.
    Sun X, Sun G, Huang Y, Hao Y, Tang X, Zhang N, Zhao L, Zhong R, Peng Y.
    Biochem Pharmacol; 2020 Jul 09; 177():113988. PubMed ID: 32330495
    [Abstract] [Full Text] [Related]

  • 9. Effect of the antitumoral alkylating agent 3-bromopyruvate on mitochondrial respiration: role of mitochondrially bound hexokinase.
    Rodrigues-Ferreira C, da Silva AP, Galina A.
    J Bioenerg Biomembr; 2012 Feb 09; 44(1):39-49. PubMed ID: 22322891
    [Abstract] [Full Text] [Related]

  • 10. Hexokinase II-derived cell-penetrating peptide targets mitochondria and triggers apoptosis in cancer cells.
    Woldetsadik AD, Vogel MC, Rabeh WM, Magzoub M.
    FASEB J; 2017 May 09; 31(5):2168-2184. PubMed ID: 28183803
    [Abstract] [Full Text] [Related]

  • 11. FV-429 induces apoptosis and inhibits glycolysis by inhibiting Akt-mediated phosphorylation of hexokinase II in MDA-MB-231 cells.
    Zhou Y, Lu N, Qiao C, Ni T, Li Z, Yu B, Guo Q, Wei L.
    Mol Carcinog; 2016 Sep 09; 55(9):1317-28. PubMed ID: 26258875
    [Abstract] [Full Text] [Related]

  • 12. Acute detachment of hexokinase II from mitochondria modestly increases oxygen consumption of the intact mouse heart.
    Nederlof R, Denis S, Lauzier B, Rosiers CD, Laakso M, Hagen J, Argmann C, Wanders R, Houtkooper RH, Hollmann MW, Houten SM, Zuurbier CJ.
    Metabolism; 2017 Jul 09; 72():66-74. PubMed ID: 28641785
    [Abstract] [Full Text] [Related]

  • 13. Flavonoid GL-V9 induces apoptosis and inhibits glycolysis of breast cancer via disrupting GSK-3β-modulated mitochondrial binding of HKII.
    Guo Y, Wei L, Zhou Y, Lu N, Tang X, Li Z, Wang X.
    Free Radic Biol Med; 2020 Jan 09; 146():119-129. PubMed ID: 31669347
    [Abstract] [Full Text] [Related]

  • 14. Astragaloside IV reduces neuronal apoptosis and parthanatos in ischemic injury by preserving mitochondrial hexokinase-II.
    Li Y, Yang Y, Zhao Y, Zhang J, Liu B, Jiao S, Zhang X.
    Free Radic Biol Med; 2019 Feb 01; 131():251-263. PubMed ID: 30502455
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of energy-producing pathways of HepG2 cells by 3-bromopyruvate.
    Pereira da Silva AP, El-Bacha T, Kyaw N, dos Santos RS, da-Silva WS, Almeida FC, Da Poian AT, Galina A.
    Biochem J; 2009 Feb 01; 417(3):717-26. PubMed ID: 18945211
    [Abstract] [Full Text] [Related]

  • 16. Gomisin J inhibits the glioma progression by inducing apoptosis and reducing HKII-regulated glycolysis.
    Li R, Yang W.
    Biochem Biophys Res Commun; 2020 Aug 13; 529(1):15-22. PubMed ID: 32560813
    [Abstract] [Full Text] [Related]

  • 17. 3-Bromopyruvate induces apoptosis in breast cancer cells by downregulating Mcl-1 through the PI3K/Akt signaling pathway.
    Liu Z, Zhang YY, Zhang QW, Zhao SR, Wu CZ, Cheng X, Jiang CC, Jiang ZW, Liu H.
    Anticancer Drugs; 2014 Apr 13; 25(4):447-55. PubMed ID: 24492287
    [Abstract] [Full Text] [Related]

  • 18. Apoptosis-inducing antitumor efficacy of hexokinase II inhibitor in hepatocellular carcinoma.
    Kim W, Yoon JH, Jeong JM, Cheon GJ, Lee TS, Yang JI, Park SC, Lee HS.
    Mol Cancer Ther; 2007 Sep 13; 6(9):2554-62. PubMed ID: 17876052
    [Abstract] [Full Text] [Related]

  • 19. Hexokinase-2 bound to mitochondria: cancer's stygian link to the "Warburg Effect" and a pivotal target for effective therapy.
    Mathupala SP, Ko YH, Pedersen PL.
    Semin Cancer Biol; 2009 Feb 13; 19(1):17-24. PubMed ID: 19101634
    [Abstract] [Full Text] [Related]

  • 20. Hexokinase II inhibition by 3-bromopyruvate sensitizes myeloid leukemic cells K-562 to anti-leukemic drug, daunorubicin.
    Rai Y, Yadav P, Kumari N, Kalra N, Bhatt AN.
    Biosci Rep; 2019 Sep 30; 39(9):. PubMed ID: 31506393
    [Abstract] [Full Text] [Related]

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