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Journal Abstract Search

513 related items for PubMed ID: 19286381

  • 21. Synthesis and biological evaluation of novel 2,4'-bis substituted diphenylamines as anticancer agents and potential epidermal growth factor receptor tyrosine kinase inhibitors.
    Abou-Seri SM.
    Eur J Med Chem; 2010 Sep; 45(9):4113-21. PubMed ID: 20580136
    [Abstract] [Full Text] [Related]

  • 22. Synthesis and biological evaluation of 2,4-diamino-6-(arylaminomethyl)pyrido[2,3-d]pyrimidines as inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase and as antiopportunistic infection and antitumor agents.
    Gangjee A, Adair OO, Queener SF.
    J Med Chem; 2003 Nov 06; 46(23):5074-82. PubMed ID: 14584957
    [Abstract] [Full Text] [Related]

  • 23. Synthesis and study of antiproliferative activity of novel thienopyrimidines on glioblastoma cells.
    Pédeboscq S, Gravier D, Casadebaig F, Hou G, Gissot A, De Giorgi F, Ichas F, Cambar J, Pometan JP.
    Eur J Med Chem; 2010 Jun 06; 45(6):2473-9. PubMed ID: 20219270
    [Abstract] [Full Text] [Related]

  • 24. Synthesis, molecular docking and evaluation of thiazolyl-pyrazoline derivatives as EGFR TK inhibitors and potential anticancer agents.
    Lv PC, Li DD, Li QS, Lu X, Xiao ZP, Zhu HL.
    Bioorg Med Chem Lett; 2011 Sep 15; 21(18):5374-7. PubMed ID: 21802290
    [Abstract] [Full Text] [Related]

  • 25. Antitumor activity of F90, an epidermal growth factor receptor tyrosine kinase inhibitor, on glioblastoma cell line SHG-44.
    Liu FJ, Gui SB, Li CZ, Sun ZL, Zhang YZ.
    Chin Med J (Engl); 2008 Sep 05; 121(17):1702-6. PubMed ID: 19024103
    [Abstract] [Full Text] [Related]

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  • 27. Design, synthesis, and biological evaluation of novel pyrimidine derivatives as CDK2 inhibitors.
    Ibrahim DA, El-Metwally AM.
    Eur J Med Chem; 2010 Mar 05; 45(3):1158-66. PubMed ID: 20045222
    [Abstract] [Full Text] [Related]

  • 28. Synthesis, EGFR Inhibition and Anti-cancer Activity of New 3,6-dimethyl-1-phenyl-4-(substituted-methoxy)pyrazolo[3,4-d] pyrimidine Derivatives.
    Bakr RB, Mehany ABM, Abdellatif KRA.
    Anticancer Agents Med Chem; 2017 Mar 05; 17(10):1389-1400. PubMed ID: 28270084
    [Abstract] [Full Text] [Related]

  • 29. Design, synthesis and biological evaluation of chrysin long-chain derivatives as potential anticancer agents.
    Lv PC, Wang KR, Li QS, Chen J, Sun J, Zhu HL.
    Bioorg Med Chem; 2010 Feb 05; 18(3):1117-23. PubMed ID: 20056425
    [Abstract] [Full Text] [Related]

  • 30. Alkynyl pyrimidines as dual EGFR/ErbB2 kinase inhibitors.
    Waterson AG, Stevens KL, Reno MJ, Zhang YM, Boros EE, Bouvier F, Rastagar A, Uehling DE, Dickerson SH, Reep B, McDonald OB, Wood ER, Rusnak DW, Alligood KJ, Rudolph SK.
    Bioorg Med Chem Lett; 2006 May 01; 16(9):2419-22. PubMed ID: 16483772
    [Abstract] [Full Text] [Related]

  • 31. Design, synthesis and biological evaluation of N-phenylsulfonylnicotinamide derivatives as novel antitumor inhibitors.
    Zhang H, Lu X, Zhang LR, Liu JJ, Yang XH, Wang XM, Zhu HL.
    Bioorg Med Chem; 2012 Feb 15; 20(4):1411-6. PubMed ID: 22277588
    [Abstract] [Full Text] [Related]

  • 32. Synthesis and biological evaluation of 4-anilinoquinolines as potent inhibitors of epidermal growth factor receptor.
    Pawar VG, Sos ML, Rode HB, Rabiller M, Heynck S, van Otterlo WA, Thomas RK, Rauh D.
    J Med Chem; 2010 Apr 08; 53(7):2892-901. PubMed ID: 20222733
    [Abstract] [Full Text] [Related]

  • 33. Inhibitors of epidermal growth factor receptor tyrosine kinase: Novel C-5 substituted anilinoquinazolines designed to target the ribose pocket.
    Ballard P, Bradbury RH, Harris CS, Hennequin LF, Hickinson M, Johnson PD, Kettle JG, Klinowska T, Leach AG, Morgentin R, Pass M, Ogilvie DJ, Olivier A, Warin N, Williams EJ.
    Bioorg Med Chem Lett; 2006 Mar 15; 16(6):1633-7. PubMed ID: 16380259
    [Abstract] [Full Text] [Related]

  • 34. Single step synthesis of new fused pyrimidine derivatives and their evaluation as potent Aurora-A kinase inhibitors.
    Shaaban MR, Saleh TS, Mayhoub AS, Farag AM.
    Eur J Med Chem; 2011 Sep 15; 46(9):3690-5. PubMed ID: 21664013
    [Abstract] [Full Text] [Related]

  • 35. Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase inhibitors and antitumor agents: synthesis and biological activities of 2,4-diamino-5-methyl-6-[(monosubstituted anilino)methyl] pyrido[2,3-d]pyrimidines.
    Gangjee A, Adair O, Queener SF.
    J Med Chem; 1999 Jul 01; 42(13):2447-55. PubMed ID: 10395486
    [Abstract] [Full Text] [Related]

  • 36. Design, synthesis, anti-tumor activity, and molecular modeling of quinazoline and pyrido[2,3-d]pyrimidine derivatives targeting epidermal growth factor receptor.
    Hou J, Wan S, Wang G, Zhang T, Li Z, Tian Y, Yu Y, Wu X, Zhang J.
    Eur J Med Chem; 2016 Aug 08; 118():276-89. PubMed ID: 27132165
    [Abstract] [Full Text] [Related]

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  • 38. Synthesis, molecular modeling and biological evaluation of 2-(benzylthio)-5-aryloxadiazole derivatives as anti-tumor agents.
    Liu K, Lu X, Zhang HJ, Sun J, Zhu HL.
    Eur J Med Chem; 2012 Jan 08; 47(1):473-8. PubMed ID: 22119130
    [Abstract] [Full Text] [Related]

  • 39. Naphthamides as novel and potent vascular endothelial growth factor receptor tyrosine kinase inhibitors: design, synthesis, and evaluation.
    Harmange JC, Weiss MM, Germain J, Polverino AJ, Borg G, Bready J, Chen D, Choquette D, Coxon A, DeMelfi T, DiPietro L, Doerr N, Estrada J, Flynn J, Graceffa RF, Harriman SP, Kaufman S, La DS, Long A, Martin MW, Neervannan S, Patel VF, Potashman M, Regal K, Roveto PM, Schrag ML, Starnes C, Tasker A, Teffera Y, Wang L, White RD, Whittington DA, Zanon R.
    J Med Chem; 2008 Mar 27; 51(6):1649-67. PubMed ID: 18324761
    [Abstract] [Full Text] [Related]

  • 40. Synthesis and evaluation of pyrido-thieno-pyrimidines as potent and selective Cdc7 kinase inhibitors.
    Zhao C, Tovar C, Yin X, Xu Q, Todorov IT, Vassilev LT, Chen L.
    Bioorg Med Chem Lett; 2009 Jan 15; 19(2):319-23. PubMed ID: 19071019
    [Abstract] [Full Text] [Related]

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