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336 related items for PubMed ID: 19293334

  • 1. Role for malic enzyme, pyruvate carboxylation, and mitochondrial malate import in glucose-stimulated insulin secretion.
    Heart E, Cline GW, Collis LP, Pongratz RL, Gray JP, Smith PJ.
    Am J Physiol Endocrinol Metab; 2009 Jun; 296(6):E1354-62. PubMed ID: 19293334
    [Abstract] [Full Text] [Related]

  • 2. The dicarboxylate carrier plays a role in mitochondrial malate transport and in the regulation of glucose-stimulated insulin secretion from rat pancreatic beta cells.
    Huypens P, Pillai R, Sheinin T, Schaefer S, Huang M, Odegaard ML, Ronnebaum SM, Wettig SD, Joseph JW.
    Diabetologia; 2011 Jan; 54(1):135-45. PubMed ID: 20949348
    [Abstract] [Full Text] [Related]

  • 3. A role for ATP-citrate lyase, malic enzyme, and pyruvate/citrate cycling in glucose-induced insulin secretion.
    Guay C, Madiraju SR, Aumais A, Joly E, Prentki M.
    J Biol Chem; 2007 Dec 07; 282(49):35657-65. PubMed ID: 17928289
    [Abstract] [Full Text] [Related]

  • 4. Feasibility of a mitochondrial pyruvate malate shuttle in pancreatic islets. Further implication of cytosolic NADPH in insulin secretion.
    MacDonald MJ.
    J Biol Chem; 1995 Aug 25; 270(34):20051-8. PubMed ID: 7650022
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  • 5. beta-Cell adaptation to insulin resistance. Increased pyruvate carboxylase and malate-pyruvate shuttle activity in islets of nondiabetic Zucker fatty rats.
    Liu YQ, Jetton TL, Leahy JL.
    J Biol Chem; 2002 Oct 18; 277(42):39163-8. PubMed ID: 12147706
    [Abstract] [Full Text] [Related]

  • 6. Silencing of cytosolic or mitochondrial isoforms of malic enzyme has no effect on glucose-stimulated insulin secretion from rodent islets.
    Ronnebaum SM, Jensen MV, Hohmeier HE, Burgess SC, Zhou YP, Qian S, MacNeil D, Howard A, Thornberry N, Ilkayeva O, Lu D, Sherry AD, Newgard CB.
    J Biol Chem; 2008 Oct 24; 283(43):28909-17. PubMed ID: 18755687
    [Abstract] [Full Text] [Related]

  • 7. Mitochondrial malic enzyme 3 is important for insulin secretion in pancreatic β-cells.
    Hasan NM, Longacre MJ, Stoker SW, Kendrick MA, MacDonald MJ.
    Mol Endocrinol; 2015 Mar 24; 29(3):396-410. PubMed ID: 25594249
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  • 8. Cytosolic and mitochondrial malic enzyme isoforms differentially control insulin secretion.
    Pongratz RL, Kibbey RG, Shulman GI, Cline GW.
    J Biol Chem; 2007 Jan 05; 282(1):200-7. PubMed ID: 17102138
    [Abstract] [Full Text] [Related]

  • 9. Chronic reduction of the cytosolic or mitochondrial NAD(P)-malic enzyme does not affect insulin secretion in a rat insulinoma cell line.
    Brown LJ, Longacre MJ, Hasan NM, Kendrick MA, Stoker SW, Macdonald MJ.
    J Biol Chem; 2009 Dec 18; 284(51):35359-67. PubMed ID: 19858194
    [Abstract] [Full Text] [Related]

  • 10. Mitochondrial Superoxide Production Decreases on Glucose-Stimulated Insulin Secretion in Pancreatic β Cells Due to Decreasing Mitochondrial Matrix NADH/NAD+ Ratio.
    Plecitá-Hlavatá L, Engstová H, Holendová B, Tauber J, Špaček T, Petrásková L, Křen V, Špačková J, Gotvaldová K, Ježek J, Dlasková A, Smolková K, Ježek P.
    Antioxid Redox Signal; 2020 Oct 20; 33(12):789-815. PubMed ID: 32517485
    [Abstract] [Full Text] [Related]

  • 11. The role of pyruvate carboxylase in insulin secretion and proliferation in rat pancreatic beta cells.
    Xu J, Han J, Long YS, Epstein PN, Liu YQ.
    Diabetologia; 2008 Nov 20; 51(11):2022-30. PubMed ID: 18769905
    [Abstract] [Full Text] [Related]

  • 12. Impaired anaplerosis and insulin secretion in insulinoma cells caused by small interfering RNA-mediated suppression of pyruvate carboxylase.
    Hasan NM, Longacre MJ, Stoker SW, Boonsaen T, Jitrapakdee S, Kendrick MA, Wallace JC, MacDonald MJ.
    J Biol Chem; 2008 Oct 17; 283(42):28048-59. PubMed ID: 18697738
    [Abstract] [Full Text] [Related]

  • 13. Chronic suppression of acetyl-CoA carboxylase 1 in beta-cells impairs insulin secretion via inhibition of glucose rather than lipid metabolism.
    Ronnebaum SM, Joseph JW, Ilkayeva O, Burgess SC, Lu D, Becker TC, Sherry AD, Newgard CB.
    J Biol Chem; 2008 May 23; 283(21):14248-56. PubMed ID: 18381287
    [Abstract] [Full Text] [Related]

  • 14. Metabolism of the insulin secretagogue methyl succinate by pancreatic islets.
    MacDonald MJ.
    Arch Biochem Biophys; 1993 Jan 23; 300(1):201-5. PubMed ID: 8424653
    [Abstract] [Full Text] [Related]

  • 15. Differences between human and rodent pancreatic islets: low pyruvate carboxylase, atp citrate lyase, and pyruvate carboxylation and high glucose-stimulated acetoacetate in human pancreatic islets.
    MacDonald MJ, Longacre MJ, Stoker SW, Kendrick M, Thonpho A, Brown LJ, Hasan NM, Jitrapakdee S, Fukao T, Hanson MS, Fernandez LA, Odorico J.
    J Biol Chem; 2011 May 27; 286(21):18383-96. PubMed ID: 21454710
    [Abstract] [Full Text] [Related]

  • 16. Inhibition of the malate-aspartate shuttle in mouse pancreatic islets abolishes glucagon secretion without affecting insulin secretion.
    Stamenkovic JA, Andersson LE, Adriaenssens AE, Bagge A, Sharoyko VV, Gribble F, Reimann F, Wollheim CB, Mulder H, Spégel P.
    Biochem J; 2015 May 15; 468(1):49-63. PubMed ID: 25731850
    [Abstract] [Full Text] [Related]

  • 17. Anaplerosis via pyruvate carboxylase is required for the fuel-induced rise in the ATP:ADP ratio in rat pancreatic islets.
    Fransson U, Rosengren AH, Schuit FC, Renström E, Mulder H.
    Diabetologia; 2006 Jul 15; 49(7):1578-86. PubMed ID: 16752176
    [Abstract] [Full Text] [Related]

  • 18. Differences between mouse and rat pancreatic islets: succinate responsiveness, malic enzyme, and anaplerosis.
    MacDonald MJ.
    Am J Physiol Endocrinol Metab; 2002 Aug 15; 283(2):E302-10. PubMed ID: 12110535
    [Abstract] [Full Text] [Related]

  • 19. Investigating the roles of mitochondrial and cytosolic malic enzyme in insulin secretion.
    Pongratz RL, Kibbey RG, Cline GW.
    Methods Enzymol; 2009 Aug 15; 457():425-50. PubMed ID: 19426882
    [Abstract] [Full Text] [Related]

  • 20. Compensatory responses to pyruvate carboxylase suppression in islet beta-cells. Preservation of glucose-stimulated insulin secretion.
    Jensen MV, Joseph JW, Ilkayeva O, Burgess S, Lu D, Ronnebaum SM, Odegaard M, Becker TC, Sherry AD, Newgard CB.
    J Biol Chem; 2006 Aug 04; 281(31):22342-22351. PubMed ID: 16740637
    [Abstract] [Full Text] [Related]

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