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Journal Abstract Search


716 related items for PubMed ID: 19293927

  • 21. The PI3K/Akt/mTOR pathway as therapeutic target in neuroblastoma.
    Fulda S.
    Curr Cancer Drug Targets; 2009 Sep; 9(6):729-37. PubMed ID: 19754357
    [Abstract] [Full Text] [Related]

  • 22. Inhibition of mTOR activity restores tamoxifen response in breast cancer cells with aberrant Akt Activity.
    deGraffenried LA, Friedrichs WE, Russell DH, Donzis EJ, Middleton AK, Silva JM, Roth RA, Hidalgo M.
    Clin Cancer Res; 2004 Dec 01; 10(23):8059-67. PubMed ID: 15585641
    [Abstract] [Full Text] [Related]

  • 23. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
    Niu NK, Wang ZL, Pan ST, Ding HQ, Au GH, He ZX, Zhou ZW, Xiao G, Yang YX, Zhang X, Yang T, Chen XW, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Dec 01; 9():1555-84. PubMed ID: 25792811
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  • 24. Effect of Ag-1031 on apoptosis in gastric cancer AGS cells and its effects on the PI3K/AKT/mTOR signaling pathway.
    Dai J, Liu D, Chen L, Sun L.
    Biotechnol Lett; 2020 Nov 01; 42(11):2447-2452. PubMed ID: 32651704
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  • 25. Targeting the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin module for acute myelogenous leukemia therapy: from bench to bedside.
    Martelli AM, Tazzari PL, Evangelisti C, Chiarini F, Blalock WL, Billi AM, Manzoli L, McCubrey JA, Cocco L.
    Curr Med Chem; 2007 Nov 01; 14(19):2009-23. PubMed ID: 17691943
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  • 26. Benzo[b]furan derivatives induces apoptosis by targeting the PI3K/Akt/mTOR signaling pathway in human breast cancer cells.
    Kamal A, Lakshma Nayak V, Nagesh N, Vishnuvardhan MV, Subba Reddy NV.
    Bioorg Chem; 2016 Jun 01; 66():124-31. PubMed ID: 27149364
    [Abstract] [Full Text] [Related]

  • 27. Characterization of LY3023414, a Novel PI3K/mTOR Dual Inhibitor Eliciting Transient Target Modulation to Impede Tumor Growth.
    Smith MC, Mader MM, Cook JA, Iversen P, Ajamie R, Perkins E, Bloem L, Yip YY, Barda DA, Waid PP, Zeckner DJ, Young DA, Sanchez-Felix M, Donoho GP, Wacheck V.
    Mol Cancer Ther; 2016 Oct 01; 15(10):2344-2356. PubMed ID: 27439478
    [Abstract] [Full Text] [Related]

  • 28. Non-immunosuppressive triazole-based small molecule induces anticancer activity against human hormone-refractory prostate cancers: the role in inhibition of PI3K/AKT/mTOR and c-Myc signaling pathways.
    Leu WJ, Swain ShP, Chan SH, Hsu JL, Liu SP, Chan ML, Yu CC, Hsu LC, Chou YL, Chang WL, Hou DR, Guh JH.
    Oncotarget; 2016 Nov 22; 7(47):76995-77009. PubMed ID: 27769069
    [Abstract] [Full Text] [Related]

  • 29. Tanshinone I attenuates the malignant biological properties of ovarian cancer by inducing apoptosis and autophagy via the inactivation of PI3K/AKT/mTOR pathway.
    Zhou J, Jiang YY, Chen H, Wu YC, Zhang L.
    Cell Prolif; 2020 Feb 22; 53(2):e12739. PubMed ID: 31820522
    [Abstract] [Full Text] [Related]

  • 30. Dual inhibition of PI3K and mTOR mitigates compensatory AKT activation and improves tamoxifen response in breast cancer.
    Chen X, Zhao M, Hao M, Sun X, Wang J, Mao Y, Zu L, Liu J, Shen Y, Wang J, Shen K.
    Mol Cancer Res; 2013 Oct 22; 11(10):1269-78. PubMed ID: 23814023
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  • 31. Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma.
    Vega F, Medeiros LJ, Leventaki V, Atwell C, Cho-Vega JH, Tian L, Claret FX, Rassidakis GZ.
    Cancer Res; 2006 Jul 01; 66(13):6589-97. PubMed ID: 16818631
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  • 32. A new diaryl urea compound, D181, induces cell cycle arrest in the G1 and M phases by targeting receptor tyrosine kinases and the microtubule skeleton.
    Zhang J, Zhou J, Ren X, Diao Y, Li H, Jiang H, Ding K, Pei D.
    Invest New Drugs; 2012 Apr 01; 30(2):490-507. PubMed ID: 21080210
    [Abstract] [Full Text] [Related]

  • 33. Salidroside induces apoptosis and protective autophagy in human gastric cancer AGS cells through the PI3K/Akt/mTOR pathway.
    Rong L, Li Z, Leng X, Li H, Ma Y, Chen Y, Song F.
    Biomed Pharmacother; 2020 Feb 01; 122():109726. PubMed ID: 31918283
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  • 34. Hydroxamic Acid Derivatives of β-Carboline/Hydroxycinnamic Acid Hybrids Inducing Apoptosis and Autophagy through the PI3K/Akt/mTOR Pathways.
    Ling Y, Li Y, Zhu R, Qian J, Liu J, Gao W, Meng C, Miao J, Xiong B, Qiu X, Ling C, Dai H, Zhang Y.
    J Nat Prod; 2019 Jun 28; 82(6):1442-1450. PubMed ID: 31120744
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  • 35. A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells.
    Sekulić A, Hudson CC, Homme JL, Yin P, Otterness DM, Karnitz LM, Abraham RT.
    Cancer Res; 2000 Jul 01; 60(13):3504-13. PubMed ID: 10910062
    [Abstract] [Full Text] [Related]

  • 36. IL-22 induced cell proliferation is regulated by PI3K/Akt/mTOR signaling cascade.
    Mitra A, Raychaudhuri SK, Raychaudhuri SP.
    Cytokine; 2012 Oct 01; 60(1):38-42. PubMed ID: 22840496
    [Abstract] [Full Text] [Related]

  • 37. Inhibition of PI3K/Akt/mTOR signaling pathway alleviates ovarian cancer chemoresistance through reversing epithelial-mesenchymal transition and decreasing cancer stem cell marker expression.
    Deng J, Bai X, Feng X, Ni J, Beretov J, Graham P, Li Y.
    BMC Cancer; 2019 Jun 24; 19(1):618. PubMed ID: 31234823
    [Abstract] [Full Text] [Related]

  • 38. Feedbacks and adaptive capabilities of the PI3K/Akt/mTOR axis in acute myeloid leukemia revealed by pathway selective inhibition and phosphoproteome analysis.
    Bertacchini J, Guida M, Accordi B, Mediani L, Martelli AM, Barozzi P, Petricoin E, Liotta L, Milani G, Giordan M, Luppi M, Forghieri F, De Pol A, Cocco L, Basso G, Marmiroli S.
    Leukemia; 2014 Nov 24; 28(11):2197-205. PubMed ID: 24699302
    [Abstract] [Full Text] [Related]

  • 39. 20(S)-Protopanaxadiol-Induced Apoptosis in MCF-7 Breast Cancer Cell Line through the Inhibition of PI3K/AKT/mTOR Signaling Pathway.
    Zhang H, Xu HL, Wang YC, Lu ZY, Yu XF, Sui DY.
    Int J Mol Sci; 2018 Apr 02; 19(4):. PubMed ID: 29614812
    [Abstract] [Full Text] [Related]

  • 40. Polyphyllin I Promoted Melanoma Cells Autophagy and Apoptosis via PI3K/Akt/mTOR Signaling Pathway.
    Long J, Pi X.
    Biomed Res Int; 2020 Apr 02; 2020():5149417. PubMed ID: 32733943
    [Abstract] [Full Text] [Related]


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