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579 related items for PubMed ID: 19305497
1. Glucose amplifies fatty acid-induced endoplasmic reticulum stress in pancreatic beta-cells via activation of mTORC1. Bachar E, Ariav Y, Ketzinel-Gilad M, Cerasi E, Kaiser N, Leibowitz G. PLoS One; 2009; 4(3):e4954. PubMed ID: 19305497 [Abstract] [Full Text] [Related]
2. Intracellular methylglyoxal induces oxidative damage to pancreatic beta cell line INS-1 cell through Ire1α-JNK and mitochondrial apoptotic pathway. Liu C, Huang Y, Zhang Y, Chen X, Kong X, Dong Y. Free Radic Res; 2017 Apr; 51(4):337-350. PubMed ID: 28488455 [Abstract] [Full Text] [Related]
3. Inositol-requiring enzyme 1α links palmitate-induced mTOR activation and lipotoxicity in hepatocytes. Chen Y, Griffiths A, Wang J, Zhang T, Song Q, Song Z. Am J Physiol Cell Physiol; 2020 Dec 01; 319(6):C1130-C1140. PubMed ID: 33052067 [Abstract] [Full Text] [Related]
4. Neuronal nitric oxide synthase protects the pancreatic beta cell from glucolipotoxicity-induced endoplasmic reticulum stress and apoptosis. Bachar E, Ariav Y, Cerasi E, Kaiser N, Leibowitz G. Diabetologia; 2010 Oct 01; 53(10):2177-87. PubMed ID: 20596694 [Abstract] [Full Text] [Related]
5. Fyn Activation of mTORC1 Stimulates the IRE1α-JNK Pathway, Leading to Cell Death. Wang Y, Yamada E, Zong H, Pessin JE. J Biol Chem; 2015 Oct 09; 290(41):24772-83. PubMed ID: 26306048 [Abstract] [Full Text] [Related]
6. Initiation and execution of lipotoxic ER stress in pancreatic beta-cells. Cunha DA, Hekerman P, Ladrière L, Bazarra-Castro A, Ortis F, Wakeham MC, Moore F, Rasschaert J, Cardozo AK, Bellomo E, Overbergh L, Mathieu C, Lupi R, Hai T, Herchuelz A, Marchetti P, Rutter GA, Eizirik DL, Cnop M. J Cell Sci; 2008 Jul 15; 121(Pt 14):2308-18. PubMed ID: 18559892 [Abstract] [Full Text] [Related]
7. Cytokine-induced beta-cell death is independent of endoplasmic reticulum stress signaling. Akerfeldt MC, Howes J, Chan JY, Stevens VA, Boubenna N, McGuire HM, King C, Biden TJ, Laybutt DR. Diabetes; 2008 Nov 15; 57(11):3034-44. PubMed ID: 18591394 [Abstract] [Full Text] [Related]
8. mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1-JNK pathway. Kato H, Nakajima S, Saito Y, Takahashi S, Katoh R, Kitamura M. Cell Death Differ; 2012 Feb 15; 19(2):310-20. PubMed ID: 21779001 [Abstract] [Full Text] [Related]
9. Glucose and fatty acids synergize to promote B-cell apoptosis through activation of glycogen synthase kinase 3β independent of JNK activation. Tanabe K, Liu Y, Hasan SD, Martinez SC, Cras-Méneur C, Welling CM, Bernal-Mizrachi E, Tanizawa Y, Rhodes CJ, Zmuda E, Hai T, Abumrad NA, Permutt MA. PLoS One; 2011 Apr 26; 6(4):e18146. PubMed ID: 21541314 [Abstract] [Full Text] [Related]
10. mTORC1-IRE1α pathway activation contributes to palmitate-elicited triglyceride secretion and cell death in hepatocytes. Wang J, Chen Y, Song Q, Griffiths A, Song Z. Exp Biol Med (Maywood); 2020 Aug 26; 245(14):1268-1279. PubMed ID: 32436749 [Abstract] [Full Text] [Related]
11. Diazoxide-induced beta-cell rest reduces endoplasmic reticulum stress in lipotoxic beta-cells. Sargsyan E, Ortsäter H, Thorn K, Bergsten P. J Endocrinol; 2008 Oct 26; 199(1):41-50. PubMed ID: 18644846 [Abstract] [Full Text] [Related]
12. AMPK activation prevents excess nutrient-induced hepatic lipid accumulation by inhibiting mTORC1 signaling and endoplasmic reticulum stress response. Li H, Min Q, Ouyang C, Lee J, He C, Zou MH, Xie Z. Biochim Biophys Acta; 2014 Sep 26; 1842(9):1844-54. PubMed ID: 25016145 [Abstract] [Full Text] [Related]
13. Non-esterified fatty acid palmitate facilitates oxidative endoplasmic reticulum stress and apoptosis of β-cells by upregulating ERO-1α expression. Sharifi S, Yamamoto T, Zeug A, Elsner M, Avezov E, Mehmeti I. Redox Biol; 2024 Jul 26; 73():103170. PubMed ID: 38692092 [Abstract] [Full Text] [Related]
14. Ubiquitin D Regulates IRE1α/c-Jun N-terminal Kinase (JNK) Protein-dependent Apoptosis in Pancreatic Beta Cells. Brozzi F, Gerlo S, Grieco FA, Juusola M, Balhuizen A, Lievens S, Gysemans C, Bugliani M, Mathieu C, Marchetti P, Tavernier J, Eizirik DL. J Biol Chem; 2016 Jun 03; 291(23):12040-56. PubMed ID: 27044747 [Abstract] [Full Text] [Related]
15. Caspase-2 and JNK activated by saturated fatty acids are not involved in apoptosis induction but modulate ER stress in human pancreatic β-cells. Němcová-Fürstová V, Balušíková K, Srámek J, James RF, Kovář J. Cell Physiol Biochem; 2013 Jun 03; 31(2-3):277-89. PubMed ID: 23466956 [Abstract] [Full Text] [Related]
16. IRE1α and TRB3 do not contribute to the disruption of proximal insulin signaling caused by palmitate in C2C12 myotubes. Pierre N, Fernández-Verdejo R, Regnier P, Vanmechelen S, Demeulder B, Francaux M. Cell Biol Int; 2016 Jan 03; 40(1):91-9. PubMed ID: 26337904 [Abstract] [Full Text] [Related]
17. Inhibition of autophagic turnover in β-cells by fatty acids and glucose leads to apoptotic cell death. Mir SU, George NM, Zahoor L, Harms R, Guinn Z, Sarvetnick NE. J Biol Chem; 2015 Mar 06; 290(10):6071-85. PubMed ID: 25548282 [Abstract] [Full Text] [Related]
18. β-cell metabolic alterations under chronic nutrient overload in rat and human islets. Vernier S, Chiu A, Schober J, Weber T, Nguyen P, Luer M, McPherson T, Wanda PE, Marshall CA, Rohatgi N, McDaniel ML, Greenberg AS, Kwon G. Islets; 2012 Mar 06; 4(6):379-92. PubMed ID: 23247575 [Abstract] [Full Text] [Related]
19. RNF13, a RING finger protein, mediates endoplasmic reticulum stress-induced apoptosis through the inositol-requiring enzyme (IRE1α)/c-Jun NH2-terminal kinase pathway. Arshad M, Ye Z, Gu X, Wong CK, Liu Y, Li D, Zhou L, Zhang Y, Bay WP, Yu VC, Li P. J Biol Chem; 2013 Mar 22; 288(12):8726-8736. PubMed ID: 23378536 [Abstract] [Full Text] [Related]
20. JNK1 protects against glucolipotoxicity-mediated beta-cell apoptosis. Prause M, Christensen DP, Billestrup N, Mandrup-Poulsen T. PLoS One; 2014 Mar 22; 9(1):e87067. PubMed ID: 24475223 [Abstract] [Full Text] [Related] Page: [Next] [New Search]