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Journal Abstract Search

189 related items for PubMed ID: 19307295

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  • 2. CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes.
    Luo G, Cunningham M, Kim S, Burn T, Lin J, Sinz M, Hamilton G, Rizzo C, Jolley S, Gilbert D, Downey A, Mudra D, Graham R, Carroll K, Xie J, Madan A, Parkinson A, Christ D, Selling B, LeCluyse E, Gan LS.
    Drug Metab Dispos; 2002 Jul; 30(7):795-804. PubMed ID: 12065438
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  • 4. Evaluation of cynomolgus monkey pregnane X receptor, primary hepatocyte, and in vivo pharmacokinetic changes in predicting human CYP3A4 induction.
    Kim S, Dinchuk JE, Anthony MN, Orcutt T, Zoeckler ME, Sauer MB, Mosure KW, Vuppugalla R, Grace JE, Simmermacher J, Dulac HA, Pizzano J, Sinz M.
    Drug Metab Dispos; 2010 Jan; 38(1):16-24. PubMed ID: 19833845
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  • 10. Application and interpretation of hPXR screening data: Validation of reporter signal requirements for prediction of clinically relevant CYP3A4 inducers.
    Cui X, Thomas A, Gerlach V, White RE, Morrison RA, Cheng KC.
    Biochem Pharmacol; 2008 Sep 01; 76(5):680-9. PubMed ID: 18647599
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  • 11. Comparison of immortalized Fa2N-4 cells and human hepatocytes as in vitro models for cytochrome P450 induction.
    Hariparsad N, Carr BA, Evers R, Chu X.
    Drug Metab Dispos; 2008 Jun 01; 36(6):1046-55. PubMed ID: 18332078
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  • 12. Impact of ritonavir, atazanavir and their combination on the CYP3A4 induction potential of efavirenz in primary human hepatocytes.
    Mugundu GM, Hariparsad N, Desai PB.
    Drug Metab Lett; 2010 Jan 01; 4(1):45-50. PubMed ID: 20201776
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  • 13. Predictive utility of in vitro rifampin induction data generated in fresh and cryopreserved human hepatocytes, Fa2N-4, and HepaRG cells.
    Templeton IE, Houston JB, Galetin A.
    Drug Metab Dispos; 2011 Oct 01; 39(10):1921-9. PubMed ID: 21771933
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  • 14. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
    Cerveny L, Svecova L, Anzenbacherova E, Vrzal R, Staud F, Dvorak Z, Ulrichova J, Anzenbacher P, Pavek P.
    Drug Metab Dispos; 2007 Jul 01; 35(7):1032-41. PubMed ID: 17392393
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  • 16. Dual roles of nuclear receptor liver X receptor α (LXRα) in the CYP3A4 expression in human hepatocytes as a positive and negative regulator.
    Watanabe K, Sakurai K, Tsuchiya Y, Yamazoe Y, Yoshinari K.
    Biochem Pharmacol; 2013 Aug 01; 86(3):428-36. PubMed ID: 23732298
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  • 17. Human pregnane X receptor activation and CYP3A4/CYP2B6 induction by 2,3-oxidosqualene:lanosterol cyclase inhibition.
    Duniec-Dmuchowski Z, Fang HL, Strom SC, Ellis E, Runge-Morris M, Kocarek TA.
    Drug Metab Dispos; 2009 Apr 01; 37(4):900-8. PubMed ID: 19158313
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  • 20. HepaRG cells as an in vitro model for evaluation of cytochrome P450 induction in humans.
    Kanebratt KP, Andersson TB.
    Drug Metab Dispos; 2008 Jan 01; 36(1):137-45. PubMed ID: 17954527
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