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Journal Abstract Search

272 related items for PubMed ID: 19308924

  • 1. Rational biosynthetic engineering for optimization of geldanamycin analogues.
    Kim W, Lee D, Hong SS, Na Z, Shin JC, Roh SH, Wu CZ, Choi O, Lee K, Shen YM, Paik SG, Lee JJ, Hong YS.
    Chembiochem; 2009 May 04; 10(7):1243-51. PubMed ID: 19308924
    [Abstract] [Full Text] [Related]

  • 2. A new post-PKS modification process in the carbamoyltransferase gene inactivation strain of Streptomyces hygroscopicus 17997.
    Li Y, He W, Wang Y, Wang Y, Shao R.
    J Antibiot (Tokyo); 2008 Jun 04; 61(6):347-55. PubMed ID: 18667782
    [Abstract] [Full Text] [Related]

  • 3. Optimizing natural products by biosynthetic engineering: discovery of nonquinone Hsp90 inhibitors.
    Zhang MQ, Gaisser S, Nur-E-Alam M, Sheehan LS, Vousden WA, Gaitatzis N, Peck G, Coates NJ, Moss SJ, Radzom M, Foster TA, Sheridan RM, Gregory MA, Roe SM, Prodromou C, Pearl L, Boyd SM, Wilkinson B, Martin CJ.
    J Med Chem; 2008 Sep 25; 51(18):5494-7. PubMed ID: 18800759
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  • 4. Characterization of tailoring genes involved in the modification of geldanamycin polyketide in Streptomyces hygroscopicus JCM4427.
    Shin JC, Na Z, Lee DH, Kim WC, Lee K, Shen YM, Paik SG, Hong YS, Lee JJ.
    J Microbiol Biotechnol; 2008 Jun 25; 18(6):1101-8. PubMed ID: 18600054
    [Abstract] [Full Text] [Related]

  • 5. Engineered biosynthesis of geldanamycin analogs for Hsp90 inhibition.
    Patel K, Piagentini M, Rascher A, Tian ZQ, Buchanan GO, Regentin R, Hu Z, Hutchinson CR, McDaniel R.
    Chem Biol; 2004 Dec 25; 11(12):1625-33. PubMed ID: 15610846
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  • 7. Mechanistic studies on Hsp90 inhibition by ansamycin derivatives.
    Onuoha SC, Mukund SR, Coulstock ET, Sengerovà B, Shaw J, McLaughlin SH, Jackson SE.
    J Mol Biol; 2007 Sep 14; 372(2):287-97. PubMed ID: 17662999
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  • 9. Synthesis and anticancer activity of geldanamycin derivatives derived from biosynthetically generated metabolites.
    Lee K, Ryu JS, Jin Y, Kim W, Kaur N, Chung SJ, Jeon YJ, Park JT, Bang JS, Lee HS, Kim TY, Lee JJ, Hong YS.
    Org Biomol Chem; 2008 Jan 21; 6(2):340-8. PubMed ID: 18175003
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  • 11. [Establishment of gene transduction system in geldanamycin producer - Streptomyces hygroscopicus 17997 and its application for gene disruption experiment].
    Gao HY, Wang YG, Gao QJ, Shang GD, Sun GZ, Yang Y.
    Sheng Wu Gong Cheng Xue Bao; 2003 Jul 21; 19(4):407-11. PubMed ID: 15969055
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  • 13. Synthetic ansamycins prepared by a ring-expanding Claisen rearrangement. Synthesis and biological evaluation of ring and conformational analogues of the Hsp90 molecular chaperone inhibitor geldanamycin.
    McErlean CS, Proisy N, Davis CJ, Boland NA, Sharp SY, Boxall K, Slawin AM, Workman P, Moody CJ.
    Org Biomol Chem; 2007 Feb 07; 5(3):531-46. PubMed ID: 17252137
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  • 15. Inactivation of putative PKS genes can double geldanamycin yield in Streptomyces hygroscopicus 17997.
    Li YH, Li M, He WQ, Wang YG, Shao RG.
    Genet Mol Res; 2013 Jun 21; 12(2):2076-85. PubMed ID: 23913387
    [Abstract] [Full Text] [Related]

  • 16. Identification of 6-demethoxy-6-methylgeldanamycin and its implication of geldanamycin biosynthesis.
    Ni S, Jiang B, Wu L, Wang Y, Zhou H, He W, Wang H, Zhu J, Li S, Li T, Zhang K.
    J Antibiot (Tokyo); 2014 Feb 21; 67(2):183-5. PubMed ID: 24105607
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  • 18. Biosynthesis of the heat-shock protein 90 inhibitor geldanamycin: new insight into the formation of the benzoquinone moiety.
    Lee D, Lee K, Cai XF, Dat NT, Boovanahalli SK, Lee M, Shin JC, Kim W, Jeong JK, Lee JS, Lee CH, Lee JH, Hong YS, Lee JJ.
    Chembiochem; 2006 Feb 21; 7(2):246-8. PubMed ID: 16381049
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  • 20. Discovery and development of heat shock protein 90 inhibitors as anticancer agents: a review of patented potent geldanamycin derivatives.
    Kim T, Keum G, Pae AN.
    Expert Opin Ther Pat; 2013 Aug 21; 23(8):919-43. PubMed ID: 23641970
    [Abstract] [Full Text] [Related]

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