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Journal Abstract Search


132 related items for PubMed ID: 1932212

  • 1. New hydrazone derivatives of adriamycin and their immunoconjugates--a correlation between acid stability and cytotoxicity.
    Kaneko T, Willner D, Monkovíc I, Knipe JO, Braslawsky GR, Greenfield RS, Vyas DM.
    Bioconjug Chem; 1991; 2(3):133-41. PubMed ID: 1932212
    [Abstract] [Full Text] [Related]

  • 2. (6-Maleimidocaproyl)hydrazone of doxorubicin--a new derivative for the preparation of immunoconjugates of doxorubicin.
    Willner D, Trail PA, Hofstead SJ, King HD, Lasch SJ, Braslawsky GR, Greenfield RS, Kaneko T, Firestone RA.
    Bioconjug Chem; 1993; 4(6):521-7. PubMed ID: 7508268
    [Abstract] [Full Text] [Related]

  • 3. Evaluation in vitro of adriamycin immunoconjugates synthesized using an acid-sensitive hydrazone linker.
    Greenfield RS, Kaneko T, Daues A, Edson MA, Fitzgerald KA, Olech LJ, Grattan JA, Spitalny GL, Braslawsky GR.
    Cancer Res; 1990 Oct 15; 50(20):6600-7. PubMed ID: 2208122
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  • 6. Monoclonal antibody conjugates of doxorubicin prepared with branched linkers: A novel method for increasing the potency of doxorubicin immunoconjugates.
    King HD, Yurgaitis D, Willner D, Firestone RA, Yang MB, Lasch SJ, Hellström KE, Trail PA.
    Bioconjug Chem; 1999 Oct 15; 10(2):279-88. PubMed ID: 10077478
    [Abstract] [Full Text] [Related]

  • 7. Enhanced tumor cell selectivity of adriamycin-monoclonal antibody conjugate via a poly(ethylene glycol)-based cleavable linker.
    Suzawa T, Nagamura S, Saito H, Ohta S, Hanai N, Kanazawa J, Okabe M, Yamasaki M.
    J Control Release; 2002 Feb 19; 79(1-3):229-42. PubMed ID: 11853934
    [Abstract] [Full Text] [Related]

  • 8. Adriamycin(hydrazone)-antibody conjugates require internalization and intracellular acid hydrolysis for antitumor activity.
    Braslawsky GR, Kadow K, Knipe J, McGoff K, Edson M, Kaneko T, Greenfield RS.
    Cancer Immunol Immunother; 1991 Feb 19; 33(6):367-74. PubMed ID: 1878890
    [Abstract] [Full Text] [Related]

  • 9. Monoclonal antibody conjugates of doxorubicin prepared with branched peptide linkers: inhibition of aggregation by methoxytriethyleneglycol chains.
    King HD, Dubowchik GM, Mastalerz H, Willner D, Hofstead SJ, Firestone RA, Lasch SJ, Trail PA.
    J Med Chem; 2002 Sep 12; 45(19):4336-43. PubMed ID: 12213074
    [Abstract] [Full Text] [Related]

  • 10. Conjugation of doxorubicin to monoclonal anti-carcinoembryonic antigen antibody via novel thiol-directed cross-linking reagents.
    Lau A, Bérubé G, Ford CH.
    Bioorg Med Chem; 1995 Oct 12; 3(10):1299-304. PubMed ID: 8564395
    [Abstract] [Full Text] [Related]

  • 11. Monoclonal antibody 44-3A6 doxorubicin immunoconjugates: comparative in vitro anti-tumor efficacy of different conjugation methods.
    Sinkule JA, Rosen ST, Radosevich JA.
    Tumour Biol; 1991 Oct 12; 12(4):198-206. PubMed ID: 1651554
    [Abstract] [Full Text] [Related]

  • 12. New coupling reagents for the preparation of disulfide cross-linked conjugates with increased stability.
    Arpicco S, Dosio F, Brusa P, Crosasso P, Cattel L.
    Bioconjug Chem; 1997 Oct 12; 8(3):327-37. PubMed ID: 9177838
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  • 14. The effect of anti-alpha-fetoprotein-adriamycin conjugate on a human hepatoma.
    Galun E, Shouval D, Adler R, Shahaar M, Wilchek M, Hurwitz E, Sela M.
    Hepatology; 1990 Apr 12; 11(4):578-84. PubMed ID: 1691730
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  • 15. [Selective cytotoxicity of antibody-ricin-A-chain conjugate for human tumor B cells. II. Comparison of activity of immunotoxins conjugated with poly- and monoclonal antibodies].
    Tonevitskiĭ AG, Zhukova OS, Rakhmanova VA, Arsen'eva EL, Bogacheva GT.
    Mol Biol (Mosk); 1988 Apr 12; 22(4):911-6. PubMed ID: 3141780
    [Abstract] [Full Text] [Related]

  • 16. Antitumor activity of doxorubicin-monoclonal antibody conjugate on human bladder cancer.
    Yu DS, Chu TM, Yeh MY, Chang SY, Ma CP, Han SH.
    J Urol; 1988 Aug 12; 140(2):415-21. PubMed ID: 3398165
    [Abstract] [Full Text] [Related]

  • 17. Antibody-penicillin-V-amidase conjugates kill antigen-positive tumor cells when combined with doxorubicin phenoxyacetamide.
    Kerr DE, Senter PD, Burnett WV, Hirschberg DL, Hellström I, Hellström KE.
    Cancer Immunol Immunother; 1990 Aug 12; 31(4):202-6. PubMed ID: 2116231
    [Abstract] [Full Text] [Related]

  • 18. BR96 conjugates of highly potent anthracyclines.
    King HD, Staab AJ, Pham-Kaplita K, Yurgaitis D, Firestone RA, Lasch SJ, Trail PA.
    Bioorg Med Chem Lett; 2003 Jul 07; 13(13):2119-22. PubMed ID: 12798317
    [Abstract] [Full Text] [Related]

  • 19. An intramolecular cyclization reaction is responsible for the in vivo inefficacy and apparent pH insensitive hydrolysis kinetics of hydrazone carboxylate derivatives of doxorubicin.
    Lee CC, Cramer AT, Szoka FC, Fréchet JM.
    Bioconjug Chem; 2006 Jul 07; 17(5):1364-8. PubMed ID: 16984149
    [Abstract] [Full Text] [Related]

  • 20. Novel doxorubicin-monoclonal anti-carcinoembryonic antigen antibody immunoconjugate activity in vitro.
    Lau A, Bérubé G, Ford CH, Gallant M.
    Bioorg Med Chem; 1995 Oct 07; 3(10):1305-12. PubMed ID: 8564396
    [Abstract] [Full Text] [Related]


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