These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Dose-related opposite modulation by nociceptin/orphanin FQ of substance P nociception in the nociceptors and spinal cord. Inoue M, Shimohira I, Yoshida A, Zimmer A, Takeshima H, Sakurada T, Ueda H. J Pharmacol Exp Ther; 1999 Oct; 291(1):308-13. PubMed ID: 10490918 [Abstract] [Full Text] [Related]
4. Intrathecally administered big dynorphin, a prodynorphin-derived peptide, produces nociceptive behavior through an N-methyl-D-aspartate receptor mechanism. Tan-No K, Esashi A, Nakagawasai O, Niijima F, Tadano T, Sakurada C, Sakurada T, Bakalkin G, Terenius L, Kisara K. Brain Res; 2002 Oct 11; 952(1):7-14. PubMed ID: 12363399 [Abstract] [Full Text] [Related]
5. [Activation of spinal MrgC receptors inhibits hyperalgesia in rats]. Jiang JP, Fu Y, Hu FJ, Hong YG. Sheng Li Xue Bao; 2015 Aug 25; 67(4):413-22. PubMed ID: 26300254 [Abstract] [Full Text] [Related]
6. Intrathecally administered D-cycloserine produces nociceptive behavior through the activation of N-methyl-D-aspartate receptor ion-channel complex acting on the glycine recognition site. Tan-No K, Esashi A, Nakagawasai O, Niijima F, Furuta S, Sato T, Satoh S, Yasuhara H, Tadano T. J Pharmacol Sci; 2007 May 25; 104(1):39-45. PubMed ID: 17452810 [Abstract] [Full Text] [Related]
7. Antinociceptive effects of spinally administered nociceptin/orphanin FQ and its N-terminal fragments on capsaicin-induced nociception. Katsuyama S, Mizoguchi H, Komatsu T, Sakurada C, Tsuzuki M, Sakurada S, Sakurada T. Peptides; 2011 Jul 25; 32(7):1530-5. PubMed ID: 21672568 [Abstract] [Full Text] [Related]
8. Nociceptin-induced scratching, biting and licking in mice: involvement of spinal NK1 receptors. Sakurada T, Katsuyama S, Sakurada S, Inoue M, Tan-No K, Kisara K, Sakurada C, Ueda H, Sasaki J. Br J Pharmacol; 1999 Aug 25; 127(7):1712-8. PubMed ID: 10455330 [Abstract] [Full Text] [Related]
9. Endogenous nociceptin/orphanin FQ signalling produces opposite spinal antinociceptive and supraspinal pronociceptive effects in the mouse formalin test: pharmacological and genetic evidences. Rizzi A, Nazzaro C, Marzola GG, Zucchini S, Trapella C, Guerrini R, Zeilhofer HU, Regoli D, Calo' G. Pain; 2006 Sep 25; 124(1-2):100-8. PubMed ID: 16697109 [Abstract] [Full Text] [Related]
10. Intrathecal high-dose morphine induces spinally-mediated behavioral responses through NMDA receptors. Sakurada T, Watanabe C, Okuda K, Sugiyama A, Moriyama T, Sakurada C, Tan-No K, Sakurada S. Brain Res Mol Brain Res; 2002 Jan 31; 98(1-2):111-8. PubMed ID: 11834301 [Abstract] [Full Text] [Related]
11. Signal pathways coupled to activation of neuronal nitric oxide synthase in the spinal cord by nociceptin/orphanin FQ. Xu L, Okuda-Ashitaka E, Matsumura S, Mabuchi T, Okamoto S, Sakimura K, Mishina M, Ito S. Neuropharmacology; 2007 Apr 31; 52(5):1318-25. PubMed ID: 17350656 [Abstract] [Full Text] [Related]
12. Involvement of tachykinin NK1 receptors in nociceptin-induced hyperalgesia in mice. Sakurada C, Sakurada S, Katsuyama S, Sasaki J, Tan-No K, Sakurada T. Brain Res; 1999 Sep 11; 841(1-2):85-92. PubMed ID: 10546991 [Abstract] [Full Text] [Related]
13. Characterization of nociceptin/orphanin FQ-induced pain responses by the novel receptor antagonist N-(4-amino-2-methylquinolin-6-yl)-2-(4-ethylphenoxymethyl) benzamide monohydrochloride. Muratani T, Minami T, Enomoto U, Sakai M, Okuda-Ashitaka E, Kiyokane K, Mori H, Ito S. J Pharmacol Exp Ther; 2002 Oct 11; 303(1):424-30. PubMed ID: 12235279 [Abstract] [Full Text] [Related]
14. The biology of Nociceptin/Orphanin FQ (N/OFQ) related to obesity, stress, anxiety, mood, and drug dependence. Witkin JM, Statnick MA, Rorick-Kehn LM, Pintar JE, Ansonoff M, Chen Y, Tucker RC, Ciccocioppo R. Pharmacol Ther; 2014 Mar 11; 141(3):283-99. PubMed ID: 24189487 [Abstract] [Full Text] [Related]
15. [Nphe1,Arg14,Lys15]nociceptin-NH2, a novel potent and selective antagonist of the nociceptin/orphanin FQ receptor. Calo G, Rizzi A, Rizzi D, Bigoni R, Guerrini R, Marzola G, Marti M, McDonald J, Morari M, Lambert DG, Salvadori S, Regoli D. Br J Pharmacol; 2002 May 11; 136(2):303-11. PubMed ID: 12010780 [Abstract] [Full Text] [Related]
16. The putative OP(4) antagonist, [Nphe(1)]nociceptin(1-13)NH(2), prevents the effects of nociceptin in neuropathic rats. Corradini L, Briscini L, Ongini E, Bertorelli R. Brain Res; 2001 Jun 29; 905(1-2):127-33. PubMed ID: 11423087 [Abstract] [Full Text] [Related]
17. Possible involvement of tachykinin NK(1) and NMDA receptors in histamine-induced hyperalgesia in mice. Sakurada S, Orito T, Sakurada C, Sato T, Hayashi T, Mobarakeh JI, Yanai K, Onodera K, Watanabe T, Sakurada T. Eur J Pharmacol; 2002 Jan 02; 434(1-2):29-34. PubMed ID: 11755162 [Abstract] [Full Text] [Related]
18. In vivo pain-inhibitory role of nociceptin/orphanin FQ in spinal cord. Inoue M, Kawashima T, Takeshima H, Calo G, Inoue A, Nakata Y, Ueda H. J Pharmacol Exp Ther; 2003 May 02; 305(2):495-501. PubMed ID: 12606680 [Abstract] [Full Text] [Related]
19. Pronociceptive effects of nociceptin/orphanin FQ (13-17) at peripheral and spinal level in mice. Inoue M, Matsunaga S, Rashid MH, Yoshida A, Mizuno K, Sakurada T, Takeshima H, Ueda H. J Pharmacol Exp Ther; 2001 Oct 02; 299(1):213-9. PubMed ID: 11561082 [Abstract] [Full Text] [Related]