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Journal Abstract Search

187 related items for PubMed ID: 19346255

  • 1. The P2Y12 antagonists, 2-methylthioadenosine 5'-monophosphate triethylammonium salt and cangrelor (ARC69931MX), can inhibit human platelet aggregation through a Gi-independent increase in cAMP levels.
    Srinivasan S, Mir F, Huang JS, Khasawneh FT, Lam SC, Le Breton GC.
    J Biol Chem; 2009 Jun 12; 284(24):16108-16117. PubMed ID: 19346255
    [Abstract] [Full Text] [Related]

  • 2. The P2Y(12) antagonists, 2MeSAMP and cangrelor, inhibit platelet activation through P2Y(12)/G(i)-dependent mechanism.
    Xiang B, Zhang G, Ren H, Sunkara M, Morris AJ, Gartner TK, Smyth SS, Li Z.
    PLoS One; 2012 Jun 12; 7(12):e51037. PubMed ID: 23236426
    [Abstract] [Full Text] [Related]

  • 3. Costimulation of the Gi-coupled ADP receptor and the Gq-coupled TXA2 receptor is required for ERK2 activation in collagen-induced platelet aggregation.
    Roger S, Pawlowski M, Habib A, Jandrot-Perrus M, Rosa JP, Bryckaert M.
    FEBS Lett; 2004 Jan 02; 556(1-3):227-35. PubMed ID: 14706855
    [Abstract] [Full Text] [Related]

  • 4. Protease-activated receptors 1 and 4 do not stimulate G(i) signaling pathways in the absence of secreted ADP and cause human platelet aggregation independently of G(i) signaling.
    Kim S, Foster C, Lecchi A, Quinton TM, Prosser DM, Jin J, Cattaneo M, Kunapuli SP.
    Blood; 2002 May 15; 99(10):3629-36. PubMed ID: 11986217
    [Abstract] [Full Text] [Related]

  • 5. Adenosine diphosphate (ADP)-induced thromboxane A(2) generation in human platelets requires coordinated signaling through integrin alpha(IIb)beta(3) and ADP receptors.
    Jin J, Quinton TM, Zhang J, Rittenhouse SE, Kunapuli SP.
    Blood; 2002 Jan 01; 99(1):193-8. PubMed ID: 11756171
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of the platelet P2Y12 receptor for adenosine diphosphate potentiates the antiplatelet effect of prostacyclin.
    Cattaneo M, Lecchi A.
    J Thromb Haemost; 2007 Mar 01; 5(3):577-82. PubMed ID: 17155953
    [Abstract] [Full Text] [Related]

  • 7. Agonist concentration-dependent differential responsivity of a human platelet purinergic receptor: pharmacological and kinetic studies of aggregation, deaggregation and shape change responses mediated by the purinergic P2Y1 receptor in vitro.
    Maayani S, Schwarz TE, Patel ND, Craddock-Royal BD, Tagliente TM.
    Platelets; 2003 Mar 01; 14(7-8):445-62. PubMed ID: 14713514
    [Abstract] [Full Text] [Related]

  • 8. Synergistic Inhibition of Both P2Y1 and P2Y12 Adenosine Diphosphate Receptors As Novel Approach to Rapidly Attenuate Platelet-Mediated Thrombosis.
    Gremmel T, Yanachkov IB, Yanachkova MI, Wright GE, Wider J, Undyala VV, Michelson AD, Frelinger AL, Przyklenk K.
    Arterioscler Thromb Vasc Biol; 2016 Mar 01; 36(3):501-9. PubMed ID: 26743169
    [Abstract] [Full Text] [Related]

  • 9. P2Y12 ADP receptor-dependent tyrosine phosphorylation of proteins of 27 and 31 kDa in thrombin-stimulated human platelets.
    Fälker K, Lange D, Presek P.
    Thromb Haemost; 2005 May 01; 93(5):880-8. PubMed ID: 15886804
    [Abstract] [Full Text] [Related]

  • 10. P2Y₁₂ and EP3 antagonists promote the inhibitory effects of natural modulators of platelet aggregation that act via cAMP.
    Iyú D, Glenn JR, White AE, Fox SC, Dovlatova N, Heptinstall S.
    Platelets; 2011 May 01; 22(7):504-15. PubMed ID: 21591981
    [Abstract] [Full Text] [Related]

  • 11. Blockade of the purinergic P2Y12 receptor greatly increases the platelet inhibitory actions of nitric oxide.
    Kirkby NS, Lundberg MH, Chan MV, Vojnovic I, Solomon AB, Emerson M, Mitchell JA, Warner TD.
    Proc Natl Acad Sci U S A; 2013 Sep 24; 110(39):15782-7. PubMed ID: 24003163
    [Abstract] [Full Text] [Related]

  • 12. On the mechanism of plasmin-induced platelet aggregation. Implications of the dual role of granule ADP.
    Ishii-Watabe A, Uchida E, Mizuguchi H, Hayakawa T.
    Biochem Pharmacol; 2000 Jun 01; 59(11):1345-55. PubMed ID: 10751543
    [Abstract] [Full Text] [Related]

  • 13. Antiplatelet action of R-99224, an active metabolite of a novel thienopyridine-type G(i)-linked P2T antagonist, CS-747.
    Sugidachi A, Asai F, Yoneda K, Iwamura R, Ogawa T, Otsuguro K, Koike H.
    Br J Pharmacol; 2001 Jan 01; 132(1):47-54. PubMed ID: 11156560
    [Abstract] [Full Text] [Related]

  • 14. 2-Alkylthio-substituted platelet P2Y12 receptor antagonists reveal pharmacological identity between the rat brain Gi-linked ADP receptors and P2Y12.
    Vasiljev KS, Uri A, Laitinen JT.
    Neuropharmacology; 2003 Jul 01; 45(1):145-54. PubMed ID: 12814667
    [Abstract] [Full Text] [Related]

  • 15. Effect of clopidogrel administration to healthy volunteers on platelet phosphorylation events triggered by ADP.
    Contreres JO, Dupuy E, Job B, Habib A, Bryckaert M, Rosa JP, Simoneau G, Herbert JM, Savi P, Levy-Toledano S.
    Br J Haematol; 2003 Feb 01; 120(4):633-42. PubMed ID: 12588350
    [Abstract] [Full Text] [Related]

  • 16. Can the PFA-100 be modified to detect P2Y12 inhibition?
    Pidcock M, Harrison P.
    J Thromb Haemost; 2006 Jun 01; 4(6):1424-6. PubMed ID: 16706997
    [No Abstract] [Full Text] [Related]

  • 17. Adenosine receptor agonists deepen the inhibition of platelet aggregation by P2Y12 antagonists.
    Boncler M, Wzorek J, Wolska N, Polak D, Watala C, Rozalski M.
    Vascul Pharmacol; 2019 Feb 01; 113():47-56. PubMed ID: 30471364
    [Abstract] [Full Text] [Related]

  • 18. Lipid rafts are required in Galpha(i) signaling downstream of the P2Y12 receptor during ADP-mediated platelet activation.
    Quinton TM, Kim S, Jin J, Kunapuli SP.
    J Thromb Haemost; 2005 May 01; 3(5):1036-41. PubMed ID: 15869601
    [Abstract] [Full Text] [Related]

  • 19. Curcumin by activation of adenosine A2A receptor stimulates protein kinase a and potentiates inhibitory effect of cangrelor on platelets.
    Rukoyatkina N, Shpakova V, Bogoutdinova A, Kharazova A, Mindukshev I, Gambaryan S.
    Biochem Biophys Res Commun; 2022 Jan 01; 586():20-26. PubMed ID: 34823218
    [Abstract] [Full Text] [Related]

  • 20. Benzoyl ATP is an antagonist of rat and human P2Y1 receptors and of platelet aggregation.
    Vigne P, Hechler B, Gachet C, Breittmayer JP, Frelin C.
    Biochem Biophys Res Commun; 1999 Mar 05; 256(1):94-7. PubMed ID: 10066429
    [Abstract] [Full Text] [Related]

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