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225 related items for PubMed ID: 19358518

  • 1. Analysis of pyridyloxobutyl and pyridylhydroxybutyl DNA adducts in extrahepatic tissues of F344 rats treated chronically with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
    Zhang S, Wang M, Villalta PW, Lindgren BR, Upadhyaya P, Lao Y, Hecht SS.
    Chem Res Toxicol; 2009 May; 22(5):926-36. PubMed ID: 19358518
    [Abstract] [Full Text] [Related]

  • 2. Quantitation of pyridylhydroxybutyl-DNA adducts in liver and lung of F-344 rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
    Upadhyaya P, Kalscheuer S, Hochalter JB, Villalta PW, Hecht SS.
    Chem Res Toxicol; 2008 Jul; 21(7):1468-76. PubMed ID: 18570389
    [Abstract] [Full Text] [Related]

  • 3. Carcinogenicity and DNA adduct formation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in F-344 rats.
    Balbo S, Johnson CS, Kovi RC, James-Yi SA, O'Sullivan MG, Wang M, Le CT, Khariwala SS, Upadhyaya P, Hecht SS.
    Carcinogenesis; 2014 Dec; 35(12):2798-806. PubMed ID: 25269804
    [Abstract] [Full Text] [Related]

  • 4. Formation and accumulation of pyridyloxobutyl DNA adducts in F344 rats chronically treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
    Lao Y, Yu N, Kassie F, Villalta PW, Hecht SS.
    Chem Res Toxicol; 2007 Feb; 20(2):235-45. PubMed ID: 17305407
    [Abstract] [Full Text] [Related]

  • 5. Mitochondrial DNA adducts in the lung and liver of F344 rats chronically treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and (S)-4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
    Stepanov I, Hecht SS.
    Chem Res Toxicol; 2009 Feb; 22(2):406-14. PubMed ID: 19166332
    [Abstract] [Full Text] [Related]

  • 6. Quantitation of pyridyloxobutyl DNA adducts in nasal and oral mucosa of rats treated chronically with enantiomers of N'-nitrosonornicotine.
    Zhang S, Wang M, Villalta PW, Lindgren BR, Lao Y, Hecht SS.
    Chem Res Toxicol; 2009 May; 22(5):949-56. PubMed ID: 19405515
    [Abstract] [Full Text] [Related]

  • 7. Pyridylhydroxybutyl and pyridyloxobutyl DNA phosphate adduct formation in rats treated chronically with enantiomers of the tobacco-specific nitrosamine metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
    Ma B, Zarth AT, Carlson ES, Villalta PW, Stepanov I, Hecht SS.
    Mutagenesis; 2017 Dec 31; 32(6):561-570. PubMed ID: 29186507
    [Abstract] [Full Text] [Related]

  • 8. Quantitation of pyridyloxobutyl DNA adducts of tobacco-specific nitrosamines in rat tissue DNA by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry.
    Lao Y, Villalta PW, Sturla SJ, Wang M, Hecht SS.
    Chem Res Toxicol; 2006 May 31; 19(5):674-82. PubMed ID: 16696570
    [Abstract] [Full Text] [Related]

  • 9. Analysis of pyridyloxobutyl DNA adducts in F344 rats chronically treated with (R)- and (S)-N'-nitrosonornicotine.
    Lao Y, Yu N, Kassie F, Villalta PW, Hecht SS.
    Chem Res Toxicol; 2007 Feb 31; 20(2):246-56. PubMed ID: 17305408
    [Abstract] [Full Text] [Related]

  • 10. Quantitation of pyridyloxobutyl-DNA adducts in tissues of rats treated chronically with (R)- or (S)-N'-nitrosonornicotine (NNN) in a carcinogenicity study.
    Zhao L, Balbo S, Wang M, Upadhyaya P, Khariwala SS, Villalta PW, Hecht SS.
    Chem Res Toxicol; 2013 Oct 21; 26(10):1526-35. PubMed ID: 24001146
    [Abstract] [Full Text] [Related]

  • 11. Analysis and Identification of 2'-Deoxyadenosine-Derived Adducts in Lung and Liver DNA of F-344 Rats Treated with the Tobacco-Specific Carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone and Enantiomers of its Metabolite 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol.
    Carlson ES, Upadhyaya P, Villalta PW, Ma B, Hecht SS.
    Chem Res Toxicol; 2018 May 21; 31(5):358-370. PubMed ID: 29651838
    [Abstract] [Full Text] [Related]

  • 12. Methyl DNA Phosphate Adduct Formation in Rats Treated Chronically with 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone and Enantiomers of Its Metabolite 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol.
    Ma B, Zarth AT, Carlson ES, Villalta PW, Upadhyaya P, Stepanov I, Hecht SS.
    Chem Res Toxicol; 2018 Jan 16; 31(1):48-57. PubMed ID: 29131934
    [Abstract] [Full Text] [Related]

  • 13. Comparative levels of O6-methylguanine, pyridyloxobutyl-, and pyridylhydroxybutyl-DNA adducts in lung and liver of rats treated chronically with the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Upadhyaya P, Lindgren BR, Hecht SS.
    Drug Metab Dispos; 2009 Jun 16; 37(6):1147-51. PubMed ID: 19324941
    [Abstract] [Full Text] [Related]

  • 14. Identification of O2-substituted pyrimidine adducts formed in reactions of 4-(acetoxymethylnitrosamino)- 1-(3-pyridyl)-1-butanone and 4-(acetoxymethylnitros- amino)-1-(3-pyridyl)-1-butanol with DNA.
    Hecht SS, Villalta PW, Sturla SJ, Cheng G, Yu N, Upadhyaya P, Wang M.
    Chem Res Toxicol; 2004 May 16; 17(5):588-97. PubMed ID: 15144215
    [Abstract] [Full Text] [Related]

  • 15. Mass Spectrometric Quantitation of Pyridyloxobutyl DNA Phosphate Adducts in Rats Chronically Treated with N'-Nitrosonornicotine.
    Li Y, Ma B, Cao Q, Balbo S, Zhao L, Upadhyaya P, Hecht SS.
    Chem Res Toxicol; 2019 Apr 15; 32(4):773-783. PubMed ID: 30740971
    [Abstract] [Full Text] [Related]

  • 16. Facile syntheses of O(2)-[4-(3-pyridyl-4-oxobut-1-yl]thymidine, the major adduct formed by tobacco specific nitrosamine 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in vivo, and its site-specifically adducted oligodeoxynucleotides.
    Krishnegowda G, Sharma AK, Krzeminski J, Gowda AS, Lin JM, Desai D, Spratt TE, Amin S.
    Chem Res Toxicol; 2011 Jun 20; 24(6):960-7. PubMed ID: 21524094
    [Abstract] [Full Text] [Related]

  • 17. Mass spectrometric analysis of relative levels of pyridyloxobutylation adducts formed in the reaction of DNA with a chemically activated form of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Sturla SJ, Scott J, Lao Y, Hecht SS, Villalta PW.
    Chem Res Toxicol; 2005 Jun 20; 18(6):1048-55. PubMed ID: 15962940
    [Abstract] [Full Text] [Related]

  • 18. Formation and distribution of NNK metabolites in an isolated perfused rat lung.
    Maertens LA, Upadhyaya P, Hecht SS, Zimmerman CL.
    Drug Metab Dispos; 2010 May 20; 38(5):752-60. PubMed ID: 20159989
    [Abstract] [Full Text] [Related]

  • 19. The pyridyloxobutyl DNA adduct, O6-[4-oxo-4-(3-pyridyl)butyl]guanine, is detected in tissues from 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-treated A/J mice.
    Thomson NM, Kenney PM, Peterson LA.
    Chem Res Toxicol; 2003 Jan 20; 16(1):1-6. PubMed ID: 12693024
    [Abstract] [Full Text] [Related]

  • 20. Identification of more than 100 structurally unique DNA-phosphate adducts formed during rat lung carcinogenesis by the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Ma B, Zarth AT, Carlson ES, Villalta PW, Upadhyaya P, Stepanov I, Hecht SS.
    Carcinogenesis; 2018 Feb 09; 39(2):232-241. PubMed ID: 29194532
    [Abstract] [Full Text] [Related]

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