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PUBMED FOR HANDHELDS

Journal Abstract Search

675 related items for PubMed ID: 19358611

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  • 3. Discovery and optimization of a new class of potent and non-chiral indole-3-carboxamide-based renin inhibitors.
    Scheiper B, Matter H, Steinhagen H, Stilz U, Böcskei Z, Fleury V, McCort G.
    Bioorg Med Chem Lett; 2010 Nov 01; 20(21):6268-72. PubMed ID: 20850300
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  • 6. Discovery of 6-ethyl-2,4-diaminopyrimidine-based small molecule renin inhibitors.
    Holsworth DD, Jalaie M, Belliotti T, Cai C, Collard W, Ferreira S, Powell NA, Stier M, Zhang E, McConnell P, Mochalkin I, Ryan MJ, Bryant J, Li T, Kasani A, Subedi R, Maiti SN, Edmunds JJ.
    Bioorg Med Chem Lett; 2007 Jul 01; 17(13):3575-80. PubMed ID: 17482464
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  • 9. Structure-based design and synthesis of novel non-zinc chelating MMP-12 inhibitors.
    Dublanchet AC, Ducrot P, Andrianjara C, O'Gara M, Morales R, Compère D, Denis A, Blais S, Cluzeau P, Courté K, Hamon J, Moreau F, Prunet ML, Tertre A.
    Bioorg Med Chem Lett; 2005 Aug 15; 15(16):3787-90. PubMed ID: 16002291
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  • 10. Design and optimization of renin inhibitors: Orally bioavailable alkyl amines.
    Tice CM, Xu Z, Yuan J, Simpson RD, Cacatian ST, Flaherty PT, Zhao W, Guo J, Ishchenko A, Singh SB, Wu Z, Scott BB, Bukhtiyarov Y, Berbaum J, Mason J, Panemangalore R, Cappiello MG, Müller D, Harrison RK, McGeehan GM, Dillard LW, Baldwin JJ, Claremon DA.
    Bioorg Med Chem Lett; 2009 Jul 01; 19(13):3541-5. PubMed ID: 19457666
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  • 11. Rational design of new bifunctional inhibitors of type II dehydroquinase.
    Toscano MD, Stewart KA, Coggins JR, Lapthorn AJ, Abell C.
    Org Biomol Chem; 2005 Sep 07; 3(17):3102-4. PubMed ID: 16106291
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  • 13. Rational design of 6-(2,4-diaminopyrimidinyl)-1,4-benzoxazin-3-ones as small molecule renin inhibitors.
    Powell NA, Ciske FL, Cai C, Holsworth DD, Mennen K, Van Huis CA, Jalaie M, Day J, Mastronardi M, McConnell P, Mochalkin I, Zhang E, Ryan MJ, Bryant J, Collard W, Ferreira S, Gu C, Collins R, Edmunds JJ.
    Bioorg Med Chem; 2007 Sep 01; 15(17):5912-49. PubMed ID: 17574423
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  • 15. Structure-based design and subsequent optimization of 2-tolyl-(1,2,3-triazol-1-yl-4-carboxamide) inhibitors of p38 MAP kinase.
    Cogan DA, Aungst R, Breinlinger EC, Fadra T, Goldberg DR, Hao MH, Kroe R, Moss N, Pargellis C, Qian KC, Swinamer AD.
    Bioorg Med Chem Lett; 2008 Jun 01; 18(11):3251-5. PubMed ID: 18462940
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  • 16. Design, synthesis and biological evaluation of 5-hydroxy, 5-substituted-pyrimidine-2,4,6-triones as potent inhibitors of gelatinases MMP-2 and MMP-9.
    Nicolotti O, Catto M, Giangreco I, Barletta M, Leonetti F, Stefanachi A, Pisani L, Cellamare S, Tortorella P, Loiodice F, Carotti A.
    Eur J Med Chem; 2012 Dec 01; 58():368-76. PubMed ID: 23149299
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  • 17. Design and synthesis of piperidine farnesyltransferase inhibitors with reduced glucuronidation potential.
    Tanaka R, Rubio A, Harn NK, Gernert D, Grese TA, Eishima J, Hara M, Yoda N, Ohashi R, Kuwabara T, Soga S, Akinaga S, Nara S, Kanda Y.
    Bioorg Med Chem; 2007 Feb 01; 15(3):1363-82. PubMed ID: 17127066
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  • 18. Design and optimization of a substituted amino propanamide series of renin inhibitors for the treatment of hypertension.
    Chen A, Bayly C, Bezençon O, Richard-Bildstein S, Dubé D, Dubé L, Gagné S, Gallant M, Gaudreault M, Grimm E, Houle R, Lacombe P, Laliberté S, Lévesque JF, Liu S, MacDonald D, Mackay B, Martin D, McKay D, Powell D, Remen L, Soisson S, Toulmond S.
    Bioorg Med Chem Lett; 2010 Apr 01; 20(7):2204-9. PubMed ID: 20206513
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  • 19. Novel prostaglandin D synthase inhibitors generated by fragment-based drug design.
    Hohwy M, Spadola L, Lundquist B, Hawtin P, Dahmén J, Groth-Clausen I, Nilsson E, Persdotter S, von Wachenfeldt K, Folmer RH, Edman K.
    J Med Chem; 2008 Apr 10; 51(7):2178-86. PubMed ID: 18341273
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