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781 related items for PubMed ID: 19363609

  • 1. Pyrrolotetrazinones deazaanalogues of temozolomide induce apoptosis in Jurkat cell line: involvement of tubulin polymerization inhibition.
    Viola G, Cecconet L, Leszl A, Basso G, Brun P, Salvador A, Dall'Acqua F, Diana P, Barraja P, Cirrincione G.
    Cancer Chemother Pharmacol; 2009 Nov; 64(6):1235-51. PubMed ID: 19363609
    [Abstract] [Full Text] [Related]

  • 2. DAT-230, a Novel Microtubule Inhibitor, Induced Aberrant Mitosis and Apoptosis in SGC-7901 Cells.
    Qiao F, Zuo D, Wang H, Li Z, Qi H, Zhang W, Wu Y.
    Biol Pharm Bull; 2013 Nov; 36(2):193-201. PubMed ID: 23370351
    [Abstract] [Full Text] [Related]

  • 3. A novel synthetic compound exerts effective anti-tumour activity in vivo via the inhibition of tubulin polymerisation in A549 cells.
    Yan J, Pang Y, Sheng J, Wang Y, Chen J, Hu J, Huang L, Li X.
    Biochem Pharmacol; 2015 Sep 01; 97(1):51-61. PubMed ID: 26212540
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  • 4. DAT-230, a novel microtubule inhibitor, exhibits potent anti-tumor activity by inducing G2/M phase arrest, apoptosis in vitro and perfusion decrease in vivo to HT-1080.
    Qiao F, Zuo D, Shen X, Qi H, Wang H, Zhang W, Wu Y.
    Cancer Chemother Pharmacol; 2012 Aug 01; 70(2):259-70. PubMed ID: 22752214
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  • 5. Inhibitory effect of oleanolic acid on hepatocellular carcinoma via ERK-p53-mediated cell cycle arrest and mitochondrial-dependent apoptosis.
    Wang X, Bai H, Zhang X, Liu J, Cao P, Liao N, Zhang W, Wang Z, Hai C.
    Carcinogenesis; 2013 Jun 01; 34(6):1323-30. PubMed ID: 23404993
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  • 6. Total alkaloids of Rubus aleaefolius Poir inhibit hepatocellular carcinoma growth in vivo and in vitro via activation of mitochondrial-dependent apoptosis.
    Zhao J, Chen X, Lin W, Wu G, Zhuang Q, Zhong X, Hong Z, Peng J.
    Int J Oncol; 2013 Mar 01; 42(3):971-8. PubMed ID: 23338043
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  • 7. MJ-29 inhibits tubulin polymerization, induces mitotic arrest, and triggers apoptosis via cyclin-dependent kinase 1-mediated Bcl-2 phosphorylation in human leukemia U937 cells.
    Yang JS, Hour MJ, Huang WW, Lin KL, Kuo SC, Chung JG.
    J Pharmacol Exp Ther; 2010 Aug 01; 334(2):477-88. PubMed ID: 20463006
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  • 8. YSL-12, a novel microtubule-destabilizing agent, exerts potent anti-tumor activity against colon cancer in vitro and in vivo.
    Cai D, Qiu Z, Yao W, Liu Y, Huang H, Liao S, Luo Q, Xie L, Lin Z.
    Cancer Chemother Pharmacol; 2016 Jun 01; 77(6):1217-29. PubMed ID: 27107592
    [Abstract] [Full Text] [Related]

  • 9. Double blockade of cell cycle at g(1)-s transition and m phase by 3-iodoacetamido benzoyl ethyl ester, a new type of tubulin ligand.
    Jiang JD, Denner L, Ling YH, Li JN, Davis A, Wang Y, Li Y, Roboz J, Wang LG, Perez-Soler R, Marcelli M, Bekesi G, Holland JF.
    Cancer Res; 2002 Nov 01; 62(21):6080-8. PubMed ID: 12414632
    [Abstract] [Full Text] [Related]

  • 10. Lx2-32c, a novel taxane derivative, exerts anti-resistance activity by initiating intrinsic apoptosis pathway in vitro and inhibits the growth of resistant tumor in vivo.
    Zhou Q, Li Y, Jin J, Lang L, Zhu Z, Fang W, Chen X.
    Biol Pharm Bull; 2012 Nov 01; 35(12):2170-9. PubMed ID: 23207769
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  • 11. Therapeutic effect of TMZ-POH on human nasopharyngeal carcinoma depends on reactive oxygen species accumulation.
    Xie L, Song X, Guo W, Wang X, Wei L, Li Y, Lv L, Wang W, Chen TC, Song X.
    Oncotarget; 2016 Jan 12; 7(2):1651-62. PubMed ID: 26625208
    [Abstract] [Full Text] [Related]

  • 12. A novel synthetic analog of Militarin, MA-1 induces mitochondrial dependent apoptosis by ROS generation in human lung cancer cells.
    Yoon DH, Lim MH, Lee YR, Sung GH, Lee TH, Jeon BH, Cho JY, Song WO, Park H, Choi S, Kim TW.
    Toxicol Appl Pharmacol; 2013 Dec 15; 273(3):659-71. PubMed ID: 24161344
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  • 13. Induction of apoptosis by chelerythrine chloride through mitochondrial pathway and Bcl-2 family proteins in human hepatoma SMMC-7721 cell.
    Zhang ZF, Guo Y, Zhang JB, Wei XH.
    Arch Pharm Res; 2011 May 15; 34(5):791-800. PubMed ID: 21656365
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  • 14. Repurposing of phentolamine as a potential anticancer agent against human castration-resistant prostate cancer: A central role on microtubule stabilization and mitochondrial apoptosis pathway.
    Ho CH, Hsu JL, Liu SP, Hsu LC, Chang WL, Chao CC, Guh JH.
    Prostate; 2015 Sep 15; 75(13):1454-66. PubMed ID: 26180030
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  • 15. Synthesis and antitumor activity of 1,5-disubstituted 1,2,4-triazoles as cis-restricted combretastatin analogues.
    Romagnoli R, Baraldi PG, Cruz-Lopez O, Lopez Cara C, Carrion MD, Brancale A, Hamel E, Chen L, Bortolozzi R, Basso G, Viola G.
    J Med Chem; 2010 May 27; 53(10):4248-58. PubMed ID: 20420439
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  • 16. Sinomenine hydrochloride inhibits human hepatocellular carcinoma cell growth in vitro and in vivo: involvement of cell cycle arrest and apoptosis induction.
    Lu XL, Zeng J, Chen YL, He PM, Wen MX, Ren MD, Hu YN, Lu GF, He SΧ.
    Int J Oncol; 2013 Jan 27; 42(1):229-38. PubMed ID: 23165705
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  • 17. Discovery of novel 2-N-aryl-substituted benzenesulfonamidoacetamides: orally bioavailable tubulin polymerization inhibitors with marked antitumor activities.
    Liu Z, Zhou Z, Tian W, Fan X, Xue D, Yu L, Yu Q, Long YQ.
    ChemMedChem; 2012 Apr 27; 7(4):680-93. PubMed ID: 22311585
    [Abstract] [Full Text] [Related]

  • 18. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
    Romagnoli R, Kimatrai Salvador M, Schiaffino Ortega S, Baraldi PG, Oliva P, Baraldi S, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Balzarini J, Liekens S, Mattiuzzo E, Basso G, Viola G.
    Eur J Med Chem; 2018 Jan 01; 143():683-698. PubMed ID: 29220790
    [Abstract] [Full Text] [Related]

  • 19. Mechanism of Arctigenin-Induced Specific Cytotoxicity against Human Hepatocellular Carcinoma Cell Lines: Hep G2 and SMMC7721.
    Lu Z, Cao S, Zhou H, Hua L, Zhang S, Cao J.
    PLoS One; 2015 Jan 01; 10(5):e0125727. PubMed ID: 25933104
    [Abstract] [Full Text] [Related]

  • 20. Unprecedented inhibition of tubulin polymerization directed by gold nanoparticles inducing cell cycle arrest and apoptosis.
    Choudhury D, Xavier PL, Chaudhari K, John R, Dasgupta AK, Pradeep T, Chakrabarti G.
    Nanoscale; 2013 May 21; 5(10):4476-89. PubMed ID: 23584723
    [Abstract] [Full Text] [Related]

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