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148 related items for PubMed ID: 19366805

  • 1. Pharmacologic abrogation of the mitotic spindle checkpoint by an indolocarbazole discovered by cellular screening efficiently kills cancer cells.
    Stolz A, Vogel C, Schneider V, Ertych N, Kienitz A, Yu H, Bastians H.
    Cancer Res; 2009 May 01; 69(9):3874-83. PubMed ID: 19366805
    [Abstract] [Full Text] [Related]

  • 2. Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores.
    Ditchfield C, Johnson VL, Tighe A, Ellston R, Haworth C, Johnson T, Mortlock A, Keen N, Taylor SS.
    J Cell Biol; 2003 Apr 28; 161(2):267-80. PubMed ID: 12719470
    [Abstract] [Full Text] [Related]

  • 3. Mechanisms of mitotic cell death induced by chemotherapy-mediated G2 checkpoint abrogation.
    Vogel C, Hager C, Bastians H.
    Cancer Res; 2007 Jan 01; 67(1):339-45. PubMed ID: 17210716
    [Abstract] [Full Text] [Related]

  • 4. Partial downregulation of MAD1 causes spindle checkpoint inactivation and aneuploidy, but does not confer resistance towards taxol.
    Kienitz A, Vogel C, Morales I, Müller R, Bastians H.
    Oncogene; 2005 Jun 16; 24(26):4301-10. PubMed ID: 15782113
    [Abstract] [Full Text] [Related]

  • 5. Localization of human TACC3 to mitotic spindles is mediated by phosphorylation on Ser558 by Aurora A: a novel pharmacodynamic method for measuring Aurora A activity.
    LeRoy PJ, Hunter JJ, Hoar KM, Burke KE, Shinde V, Ruan J, Bowman D, Galvin K, Ecsedy JA.
    Cancer Res; 2007 Jun 01; 67(11):5362-70. PubMed ID: 17545617
    [Abstract] [Full Text] [Related]

  • 6. Histone deacetylase inhibitors induce premature sister chromatid separation and override the mitotic spindle assembly checkpoint.
    Magnaghi-Jaulin L, Eot-Houllier G, Fulcrand G, Jaulin C.
    Cancer Res; 2007 Jul 01; 67(13):6360-7. PubMed ID: 17616695
    [Abstract] [Full Text] [Related]

  • 7. Novel pyrimidine-2,4-diamine derivative suppresses the cell viability and spindle assembly checkpoint activity by targeting Aurora kinases.
    Salmela AL, Pouwels J, Mäki-Jouppila J, Kohonen P, Toivonen P, Kallio L, Kallio M.
    Carcinogenesis; 2013 Feb 01; 34(2):436-45. PubMed ID: 23104179
    [Abstract] [Full Text] [Related]

  • 8. Requirement of a functional spindle checkpoint for arsenite-induced apoptosis.
    Wu YC, Yen WY, Yih LH.
    J Cell Biochem; 2008 Oct 15; 105(3):678-87. PubMed ID: 18668508
    [Abstract] [Full Text] [Related]

  • 9. The 'anaphase problem': how to disable the mitotic checkpoint when sisters split.
    Vázquez-Novelle MD, Mirchenko L, Uhlmann F, Petronczki M.
    Biochem Soc Trans; 2010 Dec 15; 38(6):1660-6. PubMed ID: 21118144
    [Abstract] [Full Text] [Related]

  • 10. MLN8054, a small-molecule inhibitor of Aurora A, causes spindle pole and chromosome congression defects leading to aneuploidy.
    Hoar K, Chakravarty A, Rabino C, Wysong D, Bowman D, Roy N, Ecsedy JA.
    Mol Cell Biol; 2007 Jun 15; 27(12):4513-25. PubMed ID: 17438137
    [Abstract] [Full Text] [Related]

  • 11. p53 activation in response to mitotic spindle damage requires signaling via BubR1-mediated phosphorylation.
    Ha GH, Baek KH, Kim HS, Jeong SJ, Kim CM, McKeon F, Lee CW.
    Cancer Res; 2007 Aug 01; 67(15):7155-64. PubMed ID: 17671183
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of histone deacetylase activity increases chromosomal instability by the aberrant regulation of mitotic checkpoint activation.
    Shin HJ, Baek KH, Jeon AH, Kim SJ, Jang KL, Sung YC, Kim CM, Lee CW.
    Oncogene; 2003 Jun 19; 22(25):3853-8. PubMed ID: 12813458
    [Abstract] [Full Text] [Related]

  • 13. ASAP is a novel substrate of the oncogenic mitotic kinase Aurora-A: phosphorylation on Ser625 is essential to spindle formation and mitosis.
    Venoux M, Basbous J, Berthenet C, Prigent C, Fernandez A, Lamb NJ, Rouquier S.
    Hum Mol Genet; 2008 Jan 15; 17(2):215-24. PubMed ID: 17925329
    [Abstract] [Full Text] [Related]

  • 14. Paclitaxel inhibits progression of mitotic cells to G1 phase by interference with spindle formation without affecting other microtubule functions during anaphase and telephase.
    Long BH, Fairchild CR.
    Cancer Res; 1994 Aug 15; 54(16):4355-61. PubMed ID: 7913875
    [Abstract] [Full Text] [Related]

  • 15. Hydrophobic bile acid-induced micronuclei formation, mitotic perturbations, and decreases in spindle checkpoint proteins: relevance to genomic instability in colon carcinogenesis.
    Payne CM, Crowley-Skillicorn C, Bernstein C, Holubec H, Moyer MP, Bernstein H.
    Nutr Cancer; 2010 Aug 15; 62(6):825-40. PubMed ID: 20661832
    [Abstract] [Full Text] [Related]

  • 16. The human mitotic checkpoint protein BubR1 regulates chromosome-spindle attachments.
    Lampson MA, Kapoor TM.
    Nat Cell Biol; 2005 Jan 15; 7(1):93-8. PubMed ID: 15592459
    [Abstract] [Full Text] [Related]

  • 17. Small-molecule inhibition of Aurora kinases triggers spindle checkpoint-independent apoptosis in cancer cells.
    Sun L, Li D, Dong X, Yu H, Dong JT, Zhang C, Lu X, Zhou J.
    Biochem Pharmacol; 2008 Mar 01; 75(5):1027-34. PubMed ID: 18163976
    [Abstract] [Full Text] [Related]

  • 18. BubR1 is required for a sustained mitotic spindle checkpoint arrest in human cancer cells treated with tubulin-targeting pyrrolo-1,5-benzoxazepines.
    Greene LM, Campiani G, Lawler M, Williams DC, Zisterer DM.
    Mol Pharmacol; 2008 Feb 01; 73(2):419-30. PubMed ID: 17991869
    [Abstract] [Full Text] [Related]

  • 19. Histone deacetylase inhibitors induce mitotic slippage.
    Stevens FE, Beamish H, Warrener R, Gabrielli B.
    Oncogene; 2008 Feb 28; 27(10):1345-54. PubMed ID: 17828304
    [Abstract] [Full Text] [Related]

  • 20. MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells.
    Michel LS, Liberal V, Chatterjee A, Kirchwegger R, Pasche B, Gerald W, Dobles M, Sorger PK, Murty VV, Benezra R.
    Nature; 2001 Jan 18; 409(6818):355-9. PubMed ID: 11201745
    [Abstract] [Full Text] [Related]

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