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Journal Abstract Search

261 related items for PubMed ID: 19376705

  • 1. Selective G-quadruplex ligands: the significant role of side chain charge density in a series of perylene derivatives.
    Micheli E, Lombardo CM, D'Ambrosio D, Franceschin M, Neidle S, Savino M.
    Bioorg Med Chem Lett; 2009 Jul 15; 19(14):3903-8. PubMed ID: 19376705
    [Abstract] [Full Text] [Related]

  • 2. 5-N-methylated quindoline derivatives as telomeric g-quadruplex stabilizing ligands: effects of 5-N positive charge on quadruplex binding affinity and cell proliferation.
    Lu YJ, Ou TM, Tan JH, Hou JQ, Shao WY, Peng D, Sun N, Wang XD, Wu WB, Bu XZ, Huang ZS, Ma DL, Wong KY, Gu LQ.
    J Med Chem; 2008 Oct 23; 51(20):6381-92. PubMed ID: 18821749
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and evaluation of 9-O-substituted berberine derivatives containing aza-aromatic terminal group as highly selective telomeric G-quadruplex stabilizing ligands.
    Ma Y, Ou TM, Tan JH, Hou JQ, Huang SL, Gu LQ, Huang ZS.
    Bioorg Med Chem Lett; 2009 Jul 01; 19(13):3414-7. PubMed ID: 19477640
    [Abstract] [Full Text] [Related]

  • 4. Disubstituted 2-phenyl-benzopyranopyrimidine derivatives as a new type of highly selective ligands for telomeric G-quadruplex DNA.
    Wu WB, Chen SH, Hou JQ, Tan JH, Ou TM, Huang SL, Li D, Gu LQ, Huang ZS.
    Org Biomol Chem; 2011 Apr 21; 9(8):2975-86. PubMed ID: 21373680
    [Abstract] [Full Text] [Related]

  • 5. Isaindigotone derivatives: a new class of highly selective ligands for telomeric G-quadruplex DNA.
    Tan JH, Ou TM, Hou JQ, Lu YJ, Huang SL, Luo HB, Wu JY, Huang ZS, Wong KY, Gu LQ.
    J Med Chem; 2009 May 14; 52(9):2825-35. PubMed ID: 19354252
    [Abstract] [Full Text] [Related]

  • 6. Disubstituted quinazoline derivatives as a new type of highly selective ligands for telomeric G-quadruplex DNA.
    Li Z, Tan JH, He JH, Long Y, Ou TM, Li D, Gu LQ, Huang ZS.
    Eur J Med Chem; 2012 Jan 14; 47(1):299-311. PubMed ID: 22104971
    [Abstract] [Full Text] [Related]

  • 7. Affinity and selectivity of G4 ligands measured by FRET.
    De Cian A, Guittat L, Shin-ya K, Riou JF, Mergny JL.
    Nucleic Acids Symp Ser (Oxf); 2005 Jan 14; (49):235-6. PubMed ID: 17150720
    [Abstract] [Full Text] [Related]

  • 8. Self-organization of G-quadruplex structures in the hTERT core promoter stabilized by polyaminic side chain perylene derivatives.
    Micheli E, Martufi M, Cacchione S, De Santis P, Savino M.
    Biophys Chem; 2010 Dec 14; 153(1):43-53. PubMed ID: 21036459
    [Abstract] [Full Text] [Related]

  • 9. The number and distances of positive charges of polyamine side chains in a series of perylene diimides significantly influence their ability to induce G-quadruplex structures and inhibit human telomerase.
    Franceschin M, Lombardo CM, Pascucci E, D'Ambrosio D, Micheli E, Bianco A, Ortaggi G, Savino M.
    Bioorg Med Chem; 2008 Mar 01; 16(5):2292-304. PubMed ID: 18165014
    [Abstract] [Full Text] [Related]

  • 10. 9-Substituted berberine derivatives as G-quadruplex stabilizing ligands in telomeric DNA.
    Zhang WJ, Ou TM, Lu YJ, Huang YY, Wu WB, Huang ZS, Zhou JL, Wong KY, Gu LQ.
    Bioorg Med Chem; 2007 Aug 15; 15(16):5493-501. PubMed ID: 17574421
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and biological evaluation of novel 4,5-bis(dialkylaminoalkyl)-substituted acridines as potent telomeric G-quadruplex ligands.
    Laronze-Cochard M, Kim YM, Brassart B, Riou JF, Laronze JY, Sapi J.
    Eur J Med Chem; 2009 Oct 15; 44(10):3880-8. PubMed ID: 19467742
    [Abstract] [Full Text] [Related]

  • 12. Homogeneous selecting of a quadruplex-binding ligand-based gold nanoparticle fluorescence resonance energy transfer assay.
    Jin Y, Li H, Bai J.
    Anal Chem; 2009 Jul 15; 81(14):5709-15. PubMed ID: 19527045
    [Abstract] [Full Text] [Related]

  • 13. Fluorescence-based melting assays for studying quadruplex ligands.
    De Cian A, Guittat L, Kaiser M, Saccà B, Amrane S, Bourdoncle A, Alberti P, Teulade-Fichou MP, Lacroix L, Mergny JL.
    Methods; 2007 Jun 15; 42(2):183-95. PubMed ID: 17472900
    [Abstract] [Full Text] [Related]

  • 14. Trisubstituted acridines as G-quadruplex telomere targeting agents. Effects of extensions of the 3,6- and 9-side chains on quadruplex binding, telomerase activity, and cell proliferation.
    Moore MJ, Schultes CM, Cuesta J, Cuenca F, Gunaratnam M, Tanious FA, Wilson WD, Neidle S.
    J Med Chem; 2006 Jan 26; 49(2):582-99. PubMed ID: 16420044
    [Abstract] [Full Text] [Related]

  • 15. Rational design of acridine-based ligands with selectivity for human telomeric quadruplexes.
    Sparapani S, Haider SM, Doria F, Gunaratnam M, Neidle S.
    J Am Chem Soc; 2010 Sep 08; 132(35):12263-72. PubMed ID: 20718414
    [Abstract] [Full Text] [Related]

  • 16. Selective interactions of perylene derivatives having different side chains with inter- and intramolecular G-quadruplex DNA structures. A correlation with telomerase inhibition.
    Rossetti L, Franceschin M, Schirripa S, Bianco A, Ortaggi G, Savino M.
    Bioorg Med Chem Lett; 2005 Jan 17; 15(2):413-20. PubMed ID: 15603964
    [Abstract] [Full Text] [Related]

  • 17. Promoting the formation and stabilization of human telomeric G-quadruplex DNA, inhibition of telomerase and cytotoxicity by phenanthroline derivatives.
    Wang L, Wen Y, Liu J, Zhou J, Li C, Wei C.
    Org Biomol Chem; 2011 Apr 21; 9(8):2648-53. PubMed ID: 21347502
    [Abstract] [Full Text] [Related]

  • 18. Pyridyl-substituted corrole isomers: synthesis and their regulation to G-quadruplex structures.
    Ma H, Zhang M, Zhang D, Huang R, Zhao Y, Yang H, Liu Y, Weng X, Zhou Y, Deng M, Xu L, Zhou X.
    Chem Asian J; 2010 Jan 04; 5(1):114-22. PubMed ID: 19937863
    [Abstract] [Full Text] [Related]

  • 19. Benzofuroquinoline derivatives had remarkable improvement of their selectivity for telomeric G-quadruplex DNA over duplex DNA upon introduction of peptidyl group.
    Long Y, Li Z, Tan JH, Ou TM, Li D, Gu LQ, Huang ZS.
    Bioconjug Chem; 2012 Sep 19; 23(9):1821-31. PubMed ID: 22871222
    [Abstract] [Full Text] [Related]

  • 20. C-11 diamino cryptolepine derivatives NSC748392, NSC748393, and NSC748394: anticancer profile and G-quadruplex stabilization.
    Lavrado J, Reszka AP, Moreira R, Neidle S, Paulo A.
    Bioorg Med Chem Lett; 2010 Dec 01; 20(23):7042-5. PubMed ID: 20952194
    [Abstract] [Full Text] [Related]

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