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648 related items for PubMed ID: 19376776

  • 1. Notch1 signaling sensitizes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human hepatocellular carcinoma cells by inhibiting Akt/Hdm2-mediated p53 degradation and up-regulating p53-dependent DR5 expression.
    Wang C, Qi R, Li N, Wang Z, An H, Zhang Q, Yu Y, Cao X.
    J Biol Chem; 2009 Jun 12; 284(24):16183-16190. PubMed ID: 19376776
    [Abstract] [Full Text] [Related]

  • 2. Quercetin sensitizes human hepatoma cells to TRAIL-induced apoptosis via Sp1-mediated DR5 up-regulation and proteasome-mediated c-FLIPS down-regulation.
    Kim JY, Kim EH, Park SS, Lim JH, Kwon TK, Choi KS.
    J Cell Biochem; 2008 Dec 15; 105(6):1386-98. PubMed ID: 18980244
    [Abstract] [Full Text] [Related]

  • 3. Proteasome inhibition sensitizes hepatocellular carcinoma cells to TRAIL by suppressing caspase inhibitors and AKT pathway.
    Inoue T, Shiraki K, Fuke H, Yamanaka Y, Miyashita K, Yamaguchi Y, Yamamoto N, Ito K, Sugimoto K, Nakano T.
    Anticancer Drugs; 2006 Mar 15; 17(3):261-8. PubMed ID: 16520654
    [Abstract] [Full Text] [Related]

  • 4. Bortezomib overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance in hepatocellular carcinoma cells in part through the inhibition of the phosphatidylinositol 3-kinase/Akt pathway.
    Chen KF, Yeh PY, Hsu C, Hsu CH, Lu YS, Hsieh HP, Chen PJ, Cheng AL.
    J Biol Chem; 2009 Apr 24; 284(17):11121-33. PubMed ID: 19261616
    [Abstract] [Full Text] [Related]

  • 5. The synthetic cannabinoid WIN 55,212-2 sensitizes hepatocellular carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by activating p8/CCAAT/enhancer binding protein homologous protein (CHOP)/death receptor 5 (DR5) axis.
    Pellerito O, Calvaruso G, Portanova P, De Blasio A, Santulli A, Vento R, Tesoriere G, Giuliano M.
    Mol Pharmacol; 2010 May 24; 77(5):854-63. PubMed ID: 20159939
    [Abstract] [Full Text] [Related]

  • 6. Notch1 signaling inhibits growth of human hepatocellular carcinoma through induction of cell cycle arrest and apoptosis.
    Qi R, An H, Yu Y, Zhang M, Liu S, Xu H, Guo Z, Cheng T, Cao X.
    Cancer Res; 2003 Dec 01; 63(23):8323-9. PubMed ID: 14678992
    [Abstract] [Full Text] [Related]

  • 7. 6-Methoxydihydrosanguinarine exhibits cytotoxicity and sensitizes TRAIL-induced apoptosis of hepatocellular carcinoma cells through ROS-mediated upregulation of DR5.
    Wang LL, Li RT, Zang ZH, Song YX, Zhang YZ, Zhang TF, Wang FZ, Hao GP, Cao L.
    Med Oncol; 2023 Aug 11; 40(9):266. PubMed ID: 37566135
    [Abstract] [Full Text] [Related]

  • 8. Triptolide sensitizes TRAIL-induced apoptosis in prostate cancer cells via p53-mediated DR5 up-regulation.
    Xiaowen H, Yi S.
    Mol Biol Rep; 2012 Sep 11; 39(9):8763-70. PubMed ID: 22707197
    [Abstract] [Full Text] [Related]

  • 9. Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs.
    Ganten TM, Haas TL, Sykora J, Stahl H, Sprick MR, Fas SC, Krueger A, Weigand MA, Grosse-Wilde A, Stremmel W, Krammer PH, Walczak H.
    Cell Death Differ; 2004 Jul 11; 11 Suppl 1():S86-96. PubMed ID: 15105837
    [Abstract] [Full Text] [Related]

  • 10. 5, 7-Dimethoxyflavone sensitizes TRAIL-induced apoptosis through DR5 upregulation in hepatocellular carcinoma cells.
    Yang JF, Cao JG, Tian L, Liu F.
    Cancer Chemother Pharmacol; 2012 Jan 11; 69(1):195-206. PubMed ID: 21660448
    [Abstract] [Full Text] [Related]

  • 11. Wogonin and related natural flavones overcome tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein resistance of tumors by down-regulation of c-FLIP protein and up-regulation of TRAIL receptor 2 expression.
    Ding J, Polier G, Köhler R, Giaisi M, Krammer PH, Li-Weber M.
    J Biol Chem; 2012 Jan 02; 287(1):641-649. PubMed ID: 22086925
    [Abstract] [Full Text] [Related]

  • 12. Azadirone, a limonoid tetranortriterpene, induces death receptors and sensitizes human cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) through a p53 protein-independent mechanism: evidence for the role of the ROS-ERK-CHOP-death receptor pathway.
    Gupta SC, Francis SK, Nair MS, Mo YY, Aggarwal BB.
    J Biol Chem; 2013 Nov 08; 288(45):32343-32356. PubMed ID: 24078627
    [Abstract] [Full Text] [Related]

  • 13. Induction of apoptosis by pectenotoxin-2 is mediated with the induction of DR4/DR5, Egr-1 and NAG-1, activation of caspases and modulation of the Bcl-2 family in p53-deficient Hep3B hepatocellular carcinoma cells.
    Shin DY, Kim GY, Kim ND, Jung JH, Kim SK, Kang HS, Choi YH.
    Oncol Rep; 2008 Feb 08; 19(2):517-26. PubMed ID: 18202802
    [Abstract] [Full Text] [Related]

  • 14. Downregulation of SNAIL sensitizes hepatocellular carcinoma cells to TRAIL-induced apoptosis by regulating the NF-κB pathway.
    Wan Z, Pan H, Liu S, Zhu J, Qi W, Fu K, Zhao T, Liang J.
    Oncol Rep; 2015 Mar 08; 33(3):1560-6. PubMed ID: 25607597
    [Abstract] [Full Text] [Related]

  • 15. TRAIL-induced apoptosis of hepatocellular carcinoma cells is augmented by targeted therapies.
    Koehler BC, Urbanik T, Vick B, Boger RJ, Heeger S, Galle PR, Schuchmann M, Schulze-Bergkamen H.
    World J Gastroenterol; 2009 Dec 21; 15(47):5924-35. PubMed ID: 20014456
    [Abstract] [Full Text] [Related]

  • 16. Interferon-alpha sensitizes human hepatoma cells to TRAIL-induced apoptosis through DR5 upregulation and NF-kappa B inactivation.
    Shigeno M, Nakao K, Ichikawa T, Suzuki K, Kawakami A, Abiru S, Miyazoe S, Nakagawa Y, Ishikawa H, Hamasaki K, Nakata K, Ishii N, Eguchi K.
    Oncogene; 2003 Mar 20; 22(11):1653-62. PubMed ID: 12642868
    [Abstract] [Full Text] [Related]

  • 17. Sulforaphane sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-resistant hepatoma cells to TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of DR5.
    Kim H, Kim EH, Eom YW, Kim WH, Kwon TK, Lee SJ, Choi KS.
    Cancer Res; 2006 Feb 01; 66(3):1740-50. PubMed ID: 16452234
    [Abstract] [Full Text] [Related]

  • 18. Camptothecin sensitizes human hepatoma Hep3B cells to TRAIL-mediated apoptosis via ROS-dependent death receptor 5 upregulation with the involvement of MAPKs.
    Jayasooriya RG, Choi YH, Hyun JW, Kim GY.
    Environ Toxicol Pharmacol; 2014 Nov 01; 38(3):959-67. PubMed ID: 25461556
    [Abstract] [Full Text] [Related]

  • 19. Dovitinib sensitizes hepatocellular carcinoma cells to TRAIL and tigatuzumab, a novel anti-DR5 antibody, through SHP-1-dependent inhibition of STAT3.
    Chen KF, Chen HL, Liu CY, Tai WT, Ichikawa K, Chen PJ, Cheng AL.
    Biochem Pharmacol; 2012 Mar 15; 83(6):769-77. PubMed ID: 22230479
    [Abstract] [Full Text] [Related]

  • 20. Sensitization of TRAIL-induced cell death by 20(S)-ginsenoside Rg3 via CHOP-mediated DR5 upregulation in human hepatocellular carcinoma cells.
    Lee JY, Jung KH, Morgan MJ, Kang YR, Lee HS, Koo GB, Hong SS, Kwon SW, Kim YS.
    Mol Cancer Ther; 2013 Mar 15; 12(3):274-85. PubMed ID: 23053497
    [Abstract] [Full Text] [Related]

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