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Journal Abstract Search

73 related items for PubMed ID: 19386778

  • 1. Fast binding kinetics and conserved 3D structure underlie the antagonistic activity of mutant TNF: useful information for designing artificial proteo-antagonists.
    Mukai Y, Nakamura T, Yoshioka Y, Shibata H, Abe Y, Nomura T, Taniai M, Ohta T, Nakagawa S, Tsunoda S, Kamada H, Yamagata Y, Tsutsumi Y.
    J Biochem; 2009 Aug; 146(2):167-72. PubMed ID: 19386778
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  • 2. Creation and X-ray structure analysis of the tumor necrosis factor receptor-1-selective mutant of a tumor necrosis factor-alpha antagonist.
    Shibata H, Yoshioka Y, Ohkawa A, Minowa K, Mukai Y, Abe Y, Taniai M, Nomura T, Kayamuro H, Nabeshi H, Sugita T, Imai S, Nagano K, Yoshikawa T, Fujita T, Nakagawa S, Yamamoto A, Ohta T, Hayakawa T, Mayumi T, Vandenabeele P, Aggarwal BB, Nakamura T, Yamagata Y, Tsunoda S, Kamada H, Tsutsumi Y.
    J Biol Chem; 2008 Jan 11; 283(2):998-1007. PubMed ID: 18003610
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  • 3. Structure-function relationship of tumor necrosis factor (TNF) and its receptor interaction based on 3D structural analysis of a fully active TNFR1-selective TNF mutant.
    Mukai Y, Shibata H, Nakamura T, Yoshioka Y, Abe Y, Nomura T, Taniai M, Ohta T, Ikemizu S, Nakagawa S, Tsunoda S, Kamada H, Yamagata Y, Tsutsumi Y.
    J Mol Biol; 2009 Jan 30; 385(4):1221-9. PubMed ID: 19084540
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  • 4. The treatment of established murine collagen-induced arthritis with a TNFR1-selective antagonistic mutant TNF.
    Shibata H, Yoshioka Y, Abe Y, Ohkawa A, Nomura T, Minowa K, Mukai Y, Nakagawa S, Taniai M, Ohta T, Kamada H, Tsunoda S, Tsutsumi Y.
    Biomaterials; 2009 Dec 30; 30(34):6638-47. PubMed ID: 19765818
    [Abstract] [Full Text] [Related]

  • 5. Therapeutic effect of PEGylated TNFR1-selective antagonistic mutant TNF in experimental autoimmune encephalomyelitis mice.
    Nomura T, Abe Y, Kamada H, Shibata H, Kayamuro H, Inoue M, Kawara T, Arita S, Furuya T, Yamashita T, Nagano K, Yoshikawa T, Yoshioka Y, Mukai Y, Nakagawa S, Taniai M, Ohta T, Serada S, Naka T, Tsunoda S, Tsutsumi Y.
    J Control Release; 2011 Jan 05; 149(1):8-14. PubMed ID: 20036293
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  • 6. The therapeutic effect of TNFR1-selective antagonistic mutant TNF-alpha in murine hepatitis models.
    Shibata H, Yoshioka Y, Ohkawa A, Abe Y, Nomura T, Mukai Y, Nakagawa S, Taniai M, Ohta T, Mayumi T, Kamada H, Tsunoda S, Tsutsumi Y.
    Cytokine; 2008 Nov 05; 44(2):229-33. PubMed ID: 18815054
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  • 7. Creation of an improved mutant TNF with TNFR1-selectivity and antagonistic activity by phage display technology.
    Nomura T, Abe Y, Kamada H, Inoue M, Kawara T, Arita S, Furuya T, Minowa K, Yoshioka Y, Shibata H, Kayamuro H, Yamashita T, Nagano K, Yoshikawa T, Mukai Y, Nakagawa S, Tsunoda S, Tsutsumi Y.
    Pharmazie; 2010 Feb 05; 65(2):93-6. PubMed ID: 20225650
    [Abstract] [Full Text] [Related]

  • 8. A novel domain antibody rationally designed against TNF-alpha using variable region of human heavy chain antibody as scaffolds to display antagonistic peptides.
    Qin W, Feng J, Li Y, Lin Z, Shen B.
    Mol Immunol; 2007 Mar 05; 44(9):2355-61. PubMed ID: 17125837
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  • 11. Functionalization of tumor necrosis factor-alpha using phage display technique and PEGylation improves its antitumor therapeutic window.
    Shibata H, Yoshioka Y, Ikemizu S, Kobayashi K, Yamamoto Y, Mukai Y, Okamoto T, Taniai M, Kawamura M, Abe Y, Nakagawa S, Hayakawa T, Nagata S, Yamagata Y, Mayumi T, Kamada H, Tsutsumi Y.
    Clin Cancer Res; 2004 Dec 15; 10(24):8293-300. PubMed ID: 15623605
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  • 15. Mutational analysis of human tumor necrosis factor-alpha.
    Shin HC, Cho KH.
    Biotechnol Lett; 2005 Jan 15; 27(2):107-12. PubMed ID: 15703873
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  • 18. Contributions of interfacial residues of human Interleukin15 to the specificity and affinity for its private alpha-receptor.
    Sakamoto S, Caaveiro JM, Sano E, Tanaka Y, Kudou M, Tsumoto K.
    J Mol Biol; 2009 Jun 26; 389(5):880-94. PubMed ID: 19406127
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