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Journal Abstract Search


185 related items for PubMed ID: 1939184

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  • 5. Substitution of glutamic acid 109 by aspartic acid alters the substrate specificity and catalytic activity of the beta-subunit in the tryptophan synthase bienzyme complex from Salmonella typhimurium.
    Brzović PS, Kayastha AM, Miles EW, Dunn MF.
    Biochemistry; 1992 Feb 04; 31(4):1180-90. PubMed ID: 1346502
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  • 7. Circular dichroism studies of the coenzyme environment in the active sites of mutant forms of the beta-subunit in the tryptophan synthase alpha 2 beta 2 complex.
    Kayastha AM, Sawa Y, Nagata S, Kanzaki H, Miles EW.
    Indian J Biochem Biophys; 1991 Feb 04; 28(5-6):352-7. PubMed ID: 1812066
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  • 10. The tryptophan synthase alpha 2 beta 2 complex. Cleavage of a flexible loop in the alpha subunit alters allosteric properties.
    Miles EW.
    J Biol Chem; 1991 Jun 15; 266(17):10715-8. PubMed ID: 1904055
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  • 13. Site-specific mutagenesis of the alpha subunit of tryptophan synthase from Salmonella typhimurium. Changing arginine 179 to leucine alters the reciprocal transmission of substrate-induced conformational changes between the alpha and beta 2 subunits.
    Kawasaki H, Bauerle R, Zon G, Ahmed SA, Miles EW.
    J Biol Chem; 1987 Aug 05; 262(22):10678-83. PubMed ID: 3112150
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  • 16. The alpha subunit of tryptophan synthase. Evidence that aspartic acid 60 is a catalytic residue and that the double alteration of residues 175 and 211 in a second-site revertant restores the proper geometry of the substrate binding site.
    Nagata S, Hyde CC, Miles EW.
    J Biol Chem; 1989 Apr 15; 264(11):6288-96. PubMed ID: 2649498
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  • 17. Site-directed mutagenesis of the alpha subunit of tryptophan synthase from Salmonella typhimurium.
    Ahmed SA, Kawasaki H, Bauerle R, Morita H, Miles EW.
    Biochem Biophys Res Commun; 1988 Mar 15; 151(2):672-8. PubMed ID: 3126743
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  • 20. Tryptophan synthase alpha subunit glutamic acid 49 is essential for activity. Studies with 19 mutants at position 49.
    Yutani K, Ogasahara K, Tsujita T, Kanemoto K, Matsumoto M, Tanaka S, Miyashita T, Matsushiro A, Sugino Y, Miles EW.
    J Biol Chem; 1987 Oct 05; 262(28):13429-33. PubMed ID: 2888759
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