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Journal Abstract Search

455 related items for PubMed ID: 19393243

  • 1. Structural basis for bivalent Smac-mimetics recognition in the IAP protein family.
    Cossu F, Milani M, Mastrangelo E, Vachette P, Servida F, Lecis D, Canevari G, Delia D, Drago C, Rizzo V, Manzoni L, Seneci P, Scolastico C, Bolognesi M.
    J Mol Biol; 2009 Sep 25; 392(3):630-44. PubMed ID: 19393243
    [Abstract] [Full Text] [Related]

  • 2. Design and characterization of bivalent Smac-based peptides as antagonists of XIAP and development and validation of a fluorescence polarization assay for XIAP containing both BIR2 and BIR3 domains.
    Nikolovska-Coleska Z, Meagher JL, Jiang S, Kawamoto SA, Gao W, Yi H, Qin D, Roller PP, Stuckey JA, Wang S.
    Anal Biochem; 2008 Mar 01; 374(1):87-98. PubMed ID: 18023397
    [Abstract] [Full Text] [Related]

  • 3. Targeting the X-linked inhibitor of apoptosis protein through 4-substituted azabicyclo[5.3.0]alkane smac mimetics. Structure, activity, and recognition principles.
    Mastrangelo E, Cossu F, Milani M, Sorrentino G, Lecis D, Delia D, Manzoni L, Drago C, Seneci P, Scolastico C, Rizzo V, Bolognesi M.
    J Mol Biol; 2008 Dec 19; 384(3):673-89. PubMed ID: 18851976
    [Abstract] [Full Text] [Related]

  • 4. Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs.
    Zobel K, Wang L, Varfolomeev E, Franklin MC, Elliott LO, Wallweber HJ, Okawa DC, Flygare JA, Vucic D, Fairbrother WJ, Deshayes K.
    ACS Chem Biol; 2006 Sep 19; 1(8):525-33. PubMed ID: 17168540
    [Abstract] [Full Text] [Related]

  • 5. Structural insight into inhibitor of apoptosis proteins recognition by a potent divalent smac-mimetic.
    Cossu F, Milani M, Vachette P, Malvezzi F, Grassi S, Lecis D, Delia D, Drago C, Seneci P, Bolognesi M, Mastrangelo E.
    PLoS One; 2012 Sep 19; 7(11):e49527. PubMed ID: 23166698
    [Abstract] [Full Text] [Related]

  • 6. Theoretical studies on the interactions of XIAP-BIR3 domain with bicyclic and tricyclic core monovalent Smac mimetics.
    Ling B, Dong L, Zhang R, Wang Z, Liu Y, Liu C.
    J Mol Graph Model; 2010 Nov 19; 29(3):354-62. PubMed ID: 20980180
    [Abstract] [Full Text] [Related]

  • 7. Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain.
    Liu Z, Sun C, Olejniczak ET, Meadows RP, Betz SF, Oost T, Herrmann J, Wu JC, Fesik SW.
    Nature; 2010 Nov 19; 408(6815):1004-8. PubMed ID: 11140637
    [Abstract] [Full Text] [Related]

  • 8. Biochemical basis for enhanced binding of peptide dimers to X-linked inhibitor of apoptosis protein.
    Splan KE, Allen JE, McLendon GL.
    Biochemistry; 2007 Oct 23; 46(42):11938-44. PubMed ID: 17910418
    [Abstract] [Full Text] [Related]

  • 9. The structure of the BIR3 domain of cIAP1 in complex with the N-terminal peptides of SMAC and caspase-9.
    Kulathila R, Vash B, Sage D, Cornell-Kennon S, Wright K, Koehn J, Stams T, Clark K, Price A.
    Acta Crystallogr D Biol Crystallogr; 2009 Jan 23; 65(Pt 1):58-66. PubMed ID: 19153467
    [Abstract] [Full Text] [Related]

  • 10. A mechanistic insight into SMAC peptide interference with XIAP-Bir2 inhibition of executioner caspases.
    Abhari BA, Davoodi J.
    J Mol Biol; 2008 Sep 05; 381(3):645-54. PubMed ID: 18619610
    [Abstract] [Full Text] [Related]

  • 11. Protein-protein recognition as a first step towards the inhibition of XIAP and Survivin anti-apoptotic proteins.
    Obiol-Pardo C, Granadino-Roldán JM, Rubio-Martinez J.
    J Mol Recognit; 2008 Sep 05; 21(3):190-204. PubMed ID: 18438971
    [Abstract] [Full Text] [Related]

  • 12. Characterization of a heterodimeric Smac-based peptide that features sequences specific to both the BIR2 and BIR3 domains of the X-linked inhibitor of apoptosis protein.
    Speer KF, Cosimini CL, Splan KE.
    Biopolymers; 2012 Sep 05; 98(2):122-30. PubMed ID: 22020922
    [Abstract] [Full Text] [Related]

  • 13. A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis.
    Srinivasula SM, Hegde R, Saleh A, Datta P, Shiozaki E, Chai J, Lee RA, Robbins PD, Fernandes-Alnemri T, Shi Y, Alnemri ES.
    Nature; 2001 Mar 01; 410(6824):112-6. PubMed ID: 11242052
    [Abstract] [Full Text] [Related]

  • 14. Solid phase synthesis of Smac/DIABLO-derived peptides using a 'Safety-Catch' resin: identification of potent XIAP BIR3 antagonists.
    Elsawy MA, Martin L, Tikhonova IG, Walker B.
    Bioorg Med Chem; 2013 Sep 01; 21(17):5004-11. PubMed ID: 23886811
    [Abstract] [Full Text] [Related]

  • 15. Interaction of a cyclic, bivalent smac mimetic with the x-linked inhibitor of apoptosis protein.
    Nikolovska-Coleska Z, Meagher JL, Jiang S, Yang CY, Qiu S, Roller PP, Stuckey JA, Wang S.
    Biochemistry; 2008 Sep 16; 47(37):9811-24. PubMed ID: 18717598
    [Abstract] [Full Text] [Related]

  • 16. Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2.
    Cossu F, Mastrangelo E, Milani M, Sorrentino G, Lecis D, Delia D, Manzoni L, Seneci P, Scolastico C, Bolognesi M.
    Biochem Biophys Res Commun; 2009 Jan 09; 378(2):162-7. PubMed ID: 18992220
    [Abstract] [Full Text] [Related]

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  • 18. Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database.
    Nikolovska-Coleska Z, Xu L, Hu Z, Tomita Y, Li P, Roller PP, Wang R, Fang X, Guo R, Zhang M, Lippman ME, Yang D, Wang S.
    J Med Chem; 2004 May 06; 47(10):2430-40. PubMed ID: 15115387
    [Abstract] [Full Text] [Related]

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  • 20. Characterization of Potent SMAC Mimetics that Sensitize Cancer Cells to TNF Family-Induced Apoptosis.
    Welsh K, Milutinovic S, Ardecky RJ, Gonzalez-Lopez M, Ganji SR, Teriete P, Finlay D, Riedl S, Matsuzawa S, Pinilla C, Houghten R, Vuori K, Reed JC, Cosford ND.
    PLoS One; 2016 May 06; 11(9):e0161952. PubMed ID: 27617834
    [Abstract] [Full Text] [Related]

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