These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

455 related items for PubMed ID: 19393243

  • 21. Design, synthesis, and characterization of a potent, nonpeptide, cell-permeable, bivalent Smac mimetic that concurrently targets both the BIR2 and BIR3 domains in XIAP.
    Sun H, Nikolovska-Coleska Z, Lu J, Meagher JL, Yang CY, Qiu S, Tomita Y, Ueda Y, Jiang S, Krajewski K, Roller PP, Stuckey JA, Wang S.
    J Am Chem Soc; 2007 Dec 12; 129(49):15279-94. PubMed ID: 17999504
    [Abstract] [Full Text] [Related]

  • 22. Structure-based design, synthesis, and evaluation of conformationally constrained mimetics of the second mitochondria-derived activator of caspase that target the X-linked inhibitor of apoptosis protein/caspase-9 interaction site.
    Sun H, Nikolovska-Coleska Z, Yang CY, Xu L, Tomita Y, Krajewski K, Roller PP, Wang S.
    J Med Chem; 2004 Aug 12; 47(17):4147-50. PubMed ID: 15293984
    [Abstract] [Full Text] [Related]

  • 23. Structure-based design and molecular profiling of Smac-mimetics selective for cellular IAPs.
    Corti A, Milani M, Lecis D, Seneci P, de Rosa M, Mastrangelo E, Cossu F.
    FEBS J; 2018 Sep 12; 285(17):3286-3298. PubMed ID: 30055105
    [Abstract] [Full Text] [Related]

  • 24. ARTS binds to a distinct domain in XIAP-BIR3 and promotes apoptosis by a mechanism that is different from other IAP-antagonists.
    Bornstein B, Gottfried Y, Edison N, Shekhtman A, Lev T, Glaser F, Larisch S.
    Apoptosis; 2011 Sep 12; 16(9):869-81. PubMed ID: 21695558
    [Abstract] [Full Text] [Related]

  • 25. Role of XIAP in inhibiting cisplatin-induced caspase activation in non-small cell lung cancer cells: a small molecule Smac mimic sensitizes for chemotherapy-induced apoptosis by enhancing caspase-3 activation.
    Checinska A, Hoogeland BS, Rodriguez JA, Giaccone G, Kruyt FA.
    Exp Cell Res; 2007 Apr 01; 313(6):1215-24. PubMed ID: 17291493
    [Abstract] [Full Text] [Related]

  • 26. Structure-based design, synthesis and biochemical testing of novel and potent Smac peptido-mimetics.
    Sun H, Nikolovska-Coleska Z, Chen J, Yang CY, Tomita Y, Pan H, Yoshioka Y, Krajewski K, Roller PP, Wang S.
    Bioorg Med Chem Lett; 2005 Feb 01; 15(3):793-7. PubMed ID: 15664859
    [Abstract] [Full Text] [Related]

  • 27. A dimeric Smac/diablo peptide directly relieves caspase-3 inhibition by XIAP. Dynamic and cooperative regulation of XIAP by Smac/Diablo.
    Gao Z, Tian Y, Wang J, Yin Q, Wu H, Li YM, Jiang X.
    J Biol Chem; 2007 Oct 19; 282(42):30718-27. PubMed ID: 17724022
    [Abstract] [Full Text] [Related]

  • 28. Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP.
    Vucic D, Franklin MC, Wallweber HJ, Das K, Eckelman BP, Shin H, Elliott LO, Kadkhodayan S, Deshayes K, Salvesen GS, Fairbrother WJ.
    Biochem J; 2005 Jan 01; 385(Pt 1):11-20. PubMed ID: 15485396
    [Abstract] [Full Text] [Related]

  • 29. The activator of apoptosis Smac-DIABLO acts as a tetramer in solution.
    Mastrangelo E, Vachette P, Cossu F, Malvezzi F, Bolognesi M, Milani M.
    Biophys J; 2015 Feb 03; 108(3):714-23. PubMed ID: 25650938
    [Abstract] [Full Text] [Related]

  • 30. Requirement of both the second and third BIR domains for the relief of X-linked inhibitor of apoptosis protein (XIAP)-mediated caspase inhibition by Smac.
    Huang Y, Rich RL, Myszka DG, Wu H.
    J Biol Chem; 2003 Dec 05; 278(49):49517-22. PubMed ID: 14512414
    [Abstract] [Full Text] [Related]

  • 31. Smac mimetic Birinapant induces apoptosis and enhances TRAIL potency in inflammatory breast cancer cells in an IAP-dependent and TNF-α-independent mechanism.
    Allensworth JL, Sauer SJ, Lyerly HK, Morse MA, Devi GR.
    Breast Cancer Res Treat; 2013 Jan 05; 137(2):359-71. PubMed ID: 23225169
    [Abstract] [Full Text] [Related]

  • 32. Structure-activity based study of the Smac-binding pocket within the BIR3 domain of XIAP.
    Wist AD, Gu L, Riedl SJ, Shi Y, McLendon GL.
    Bioorg Med Chem; 2007 Apr 15; 15(8):2935-43. PubMed ID: 17336535
    [Abstract] [Full Text] [Related]

  • 33. Structure and function analysis of peptide antagonists of melanoma inhibitor of apoptosis (ML-IAP).
    Franklin MC, Kadkhodayan S, Ackerly H, Alexandru D, Distefano MD, Elliott LO, Flygare JA, Mausisa G, Okawa DC, Ong D, Vucic D, Deshayes K, Fairbrother WJ.
    Biochemistry; 2003 Jul 15; 42(27):8223-31. PubMed ID: 12846571
    [Abstract] [Full Text] [Related]

  • 34. Identification of mammalian mitochondrial proteins that interact with IAPs via N-terminal IAP binding motifs.
    Verhagen AM, Kratina TK, Hawkins CJ, Silke J, Ekert PG, Vaux DL.
    Cell Death Differ; 2007 Feb 15; 14(2):348-57. PubMed ID: 16794601
    [Abstract] [Full Text] [Related]

  • 35. Development and optimization of a binding assay for the XIAP BIR3 domain using fluorescence polarization.
    Nikolovska-Coleska Z, Wang R, Fang X, Pan H, Tomita Y, Li P, Roller PP, Krajewski K, Saito NG, Stuckey JA, Wang S.
    Anal Biochem; 2004 Sep 15; 332(2):261-73. PubMed ID: 15325294
    [Abstract] [Full Text] [Related]

  • 36. Rapid induction of IAP family proteins and Smac/DIABLO expression after proapoptotic stimulation with doxorubicin in RPMI 8226 multiple myeloma cells.
    Abe S, Hasegawa M, Yamamoto K, Kurata M, Nakagawa Y, Suzuki K, Takizawa T, Kitagawa M.
    Exp Mol Pathol; 2007 Dec 15; 83(3):405-12. PubMed ID: 17521628
    [Abstract] [Full Text] [Related]

  • 37. Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain.
    Huang Y, Park YC, Rich RL, Segal D, Myszka DG, Wu H.
    Cell; 2001 Mar 09; 104(5):781-90. PubMed ID: 11257231
    [Abstract] [Full Text] [Related]

  • 38. Conformational selection, dynamic restriction and the hydrophobic effect coupled to stabilization of the BIR3 domain of the human X-linked inhibitor of apoptosis protein by the tetrapeptide AVPI.
    de Souza TL, Sanches D, Gonçalves RB, da RochaPita SS, Pascutti PG, Bianconi ML, de Almeida FC, Silva JL, de Oliveira AC.
    Biophys Chem; 2010 Nov 09; 152(1-3):99-108. PubMed ID: 20843595
    [Abstract] [Full Text] [Related]

  • 39. Molecular interaction between HAX-1 and XIAP inhibits apoptosis.
    Kang YJ, Jang M, Park YK, Kang S, Bae KH, Cho S, Lee CK, Park BC, Chi SW, Park SG.
    Biochem Biophys Res Commun; 2010 Mar 19; 393(4):794-9. PubMed ID: 20171186
    [Abstract] [Full Text] [Related]

  • 40. Disturbed expression of the apoptosis regulators XIAP, XAF1, and Smac/DIABLO in gastric adenocarcinomas.
    Shibata T, Mahotka C, Wethkamp N, Heikaus S, Gabbert HE, Ramp U.
    Diagn Mol Pathol; 2007 Mar 19; 16(1):1-8. PubMed ID: 17471152
    [Abstract] [Full Text] [Related]

    Page: [Previous] [Next] [New Search]
    of 23.