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Journal Abstract Search

572 related items for PubMed ID: 19401496

  • 1. [N-methyl-3H3]AZ10419369 binding to the 5-HT1B receptor: in vitro characterization and in vivo receptor occupancy.
    Maier DL, Sobotka-Briner C, Ding M, Powell ME, Jiang Q, Hill G, Heys JR, Elmore CS, Pierson ME, Mrzljak L.
    J Pharmacol Exp Ther; 2009 Jul; 330(1):342-51. PubMed ID: 19401496
    [Abstract] [Full Text] [Related]

  • 2. [11C]AZ10419369: a selective 5-HT1B receptor radioligand suitable for positron emission tomography (PET). Characterization in the primate brain.
    Pierson ME, Andersson J, Nyberg S, McCarthy DJ, Finnema SJ, Varnäs K, Takano A, Karlsson P, Gulyás B, Medd AM, Lee CM, Powell ME, Heys JR, Potts W, Seneca N, Mrzljak L, Farde L, Halldin C.
    Neuroimage; 2008 Jul 01; 41(3):1075-85. PubMed ID: 18434202
    [Abstract] [Full Text] [Related]

  • 3. In vitro characterization of AR-A000002, a novel 5-hydroxytryptamine(1B) autoreceptor antagonist.
    Ahlgren C, Eriksson A, Tellefors P, Ross SB, Stenfors C, Malmberg A.
    Eur J Pharmacol; 2004 Sep 19; 499(1-2):67-75. PubMed ID: 15363952
    [Abstract] [Full Text] [Related]

  • 4. Preclinical pharmacology and pharmacokinetics of AZD3783, a selective 5-hydroxytryptamine 1B receptor antagonist.
    Zhang M, Zhou D, Wang Y, Maier DL, Widzowski DV, Sobotka-Briner CD, Brockel BJ, Potts WM, Shenvi AB, Bernstein PR, Pierson ME.
    J Pharmacol Exp Ther; 2011 Nov 19; 339(2):567-78. PubMed ID: 21825000
    [Abstract] [Full Text] [Related]

  • 5. SB-616234-A (1-[6-(cis-3,5-dimethylpiperazin-1-yl)-2,3-dihydro-5-methoxyindol-1-yl]-1-[2'methyl-4'-(5-methyl-1,2,3-oxadiazol-3-yl)biphenyl-4-yl]methanone hydrochloride): a novel, potent and selective 5-HT1B receptor antagonist.
    Scott C, Langmead CJ, Clarke KL, Wyman P, Smith PW, Starr KR, Dawson LA, Price GW, Hagan JJ, Watson J.
    Neuropharmacology; 2006 Jun 19; 50(8):984-90. PubMed ID: 16546225
    [Abstract] [Full Text] [Related]

  • 6. (R)-(+)-2-[[[3-(Morpholinomethyl)-2H-chromen-8-yl]oxy]methyl] morpholine methanesulfonate: a new selective rat 5-hydroxytryptamine1B receptor antagonist.
    Berg S, Larsson LG, Rényi L, Ross SB, Thorberg SO, Thorell-Svantesson G.
    J Med Chem; 1998 May 21; 41(11):1934-42. PubMed ID: 9599242
    [Abstract] [Full Text] [Related]

  • 7. Dose-dependent binding of AZD3783 to brain 5-HT1B receptors in non-human primates and human subjects: a positron emission tomography study with [11C]AZ10419369.
    Varnäs K, Nyberg S, Karlsson P, Pierson ME, Kågedal M, Cselényi Z, McCarthy D, Xiao A, Zhang M, Halldin C, Farde L.
    Psychopharmacology (Berl); 2011 Feb 21; 213(2-3):533-45. PubMed ID: 21234549
    [Abstract] [Full Text] [Related]

  • 8. Behavioral pharmacology of AR-A000002, a novel, selective 5-hydroxytryptamine(1B) antagonist.
    Hudzik TJ, Yanek M, Porrey T, Evenden J, Paronis C, Mastrangelo M, Ryan C, Ross S, Stenfors C.
    J Pharmacol Exp Ther; 2003 Mar 21; 304(3):1072-84. PubMed ID: 12604684
    [Abstract] [Full Text] [Related]

  • 9. The selective 5-HT1B receptor inverse agonist 1'-methyl-5-[[2'-methyl-4'-(5-methyl-1,2, 4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydro- spiro[furo[2,3-f]indole-3,4'-piperidine] (SB-224289) potently blocks terminal 5-HT autoreceptor function both in vitro and in vivo.
    Gaster LM, Blaney FE, Davies S, Duckworth DM, Ham P, Jenkins S, Jennings AJ, Joiner GF, King FD, Mulholland KR, Wyman PA, Hagan JJ, Hatcher J, Jones BJ, Middlemiss DN, Price GW, Riley G, Roberts C, Routledge C, Selkirk J, Slade PD.
    J Med Chem; 1998 Apr 09; 41(8):1218-35. PubMed ID: 9548813
    [Abstract] [Full Text] [Related]

  • 10. Pharmacology of a novel selective 5-hydroxytryptamine1B receptor antagonist, AR-A000002.
    Stenfors C, Hallerbäck T, Larsson LG, Wallsten C, Ross SB.
    Naunyn Schmiedebergs Arch Pharmacol; 2004 Mar 09; 369(3):330-7. PubMed ID: 14758468
    [Abstract] [Full Text] [Related]

  • 11. 5-Hydroxytryptamine1B receptor-mediated contraction of rabbit saphenous vein and basilar artery: role of vascular endothelium.
    Bhattacharya A, Schenck KW, Xu YC, Nisenbaum L, Galbreath E, Cohen ML.
    J Pharmacol Exp Ther; 2004 May 09; 309(2):825-32. PubMed ID: 14724223
    [Abstract] [Full Text] [Related]

  • 12. Quantitative analysis of [11C]AZ10419369 binding to 5-HT1B receptors in human brain.
    Varnäs K, Nyberg S, Halldin C, Varrone A, Takano A, Karlsson P, Andersson J, McCarthy D, Smith M, Pierson ME, Söderström J, Farde L.
    J Cereb Blood Flow Metab; 2011 Jan 09; 31(1):113-23. PubMed ID: 20424633
    [Abstract] [Full Text] [Related]

  • 13. 5-HT1B receptor antagonist properties of novel arylpiperazide derivatives of 1-naphthylpiperazine.
    Jorand-Lebrun C, Pauwels PJ, Palmier C, Moret C, Chopin P, Perez M, Marien M, Halazy S.
    J Med Chem; 1997 Nov 21; 40(24):3974-8. PubMed ID: 9397179
    [Abstract] [Full Text] [Related]

  • 14. Autoradiographic characterisation of [35S]GTPgammaS binding stimulation mediated by 5-HT1B receptor in postmortem human brain.
    Mostany R, Pazos A, Castro ME.
    Neuropharmacology; 2005 Jan 21; 48(1):25-33. PubMed ID: 15617724
    [Abstract] [Full Text] [Related]

  • 15. Pre-clinical validation of a novel alpha-7 nicotinic receptor radiotracer, [(3)H]AZ11637326: target localization, biodistribution and ligand occupancy in the rat brain.
    Maier DL, Hill G, Ding M, Tuke D, Einstein E, Gurley D, Gordon JC, Bock MJ, Smith JS, Bialecki R, Eisman M, Elmore CS, Werkheiser JL.
    Neuropharmacology; 2011 Jan 21; 61(1-2):161-71. PubMed ID: 21497612
    [Abstract] [Full Text] [Related]

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  • 18. Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor.
    Grundt P, Carlson EE, Cao J, Bennett CJ, McElveen E, Taylor M, Luedtke RR, Newman AH.
    J Med Chem; 2005 Feb 10; 48(3):839-48. PubMed ID: 15689168
    [Abstract] [Full Text] [Related]

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  • 20. SB-224289--a novel selective (human) 5-HT1B receptor antagonist with negative intrinsic activity.
    Selkirk JV, Scott C, Ho M, Burton MJ, Watson J, Gaster LM, Collin L, Jones BJ, Middlemiss DN, Price GW.
    Br J Pharmacol; 1998 Sep 10; 125(1):202-8. PubMed ID: 9776361
    [Abstract] [Full Text] [Related]

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