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525 related items for PubMed ID: 19408892

  • 1. Biotransformation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in lung tissue from mouse, rat, hamster, and man.
    Richter E, Engl J, Friesenegger S, Tricker AR.
    Chem Res Toxicol; 2009 Jun; 22(6):1008-17. PubMed ID: 19408892
    [Abstract] [Full Text] [Related]

  • 2. Use of precision-cut tissue slices in organ culture to study metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by hamster lung, liver and kidney.
    Richter E, Friesenegger S, Engl J, Tricker AR.
    Toxicology; 2000 Apr 03; 144(1-3):83-91. PubMed ID: 10781874
    [Abstract] [Full Text] [Related]

  • 3. Comparative metabolism of the tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol by rat cytochrome P450 2A3 and human cytochrome P450 2A13.
    Jalas JR, Ding X, Murphy SE.
    Drug Metab Dispos; 2003 Oct 03; 31(10):1199-202. PubMed ID: 12975327
    [Abstract] [Full Text] [Related]

  • 4. Cell specificity for the pulmonary metabolism of tobacco-specific nitrosamines in the Fischer rat.
    Belinsky SA, White CM, Trushin N, Hecht SS.
    Carcinogenesis; 1989 Dec 03; 10(12):2269-74. PubMed ID: 2591016
    [Abstract] [Full Text] [Related]

  • 5. Metabolism and DNA single strand breaks induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and its analogues in primary culture of rat hepatocytes.
    Liu LL, Alaoui-Jamali MA, el Alami N, Castonguay A.
    Cancer Res; 1990 Mar 15; 50(6):1810-6. PubMed ID: 2306734
    [Abstract] [Full Text] [Related]

  • 6. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in isolated rat lung and liver.
    Schrader E, Hirsch-Ernst KI, Richter E, Foth H.
    Naunyn Schmiedebergs Arch Pharmacol; 1998 Mar 15; 357(3):336-43. PubMed ID: 9550307
    [Abstract] [Full Text] [Related]

  • 7. Effect of phenethyl isothiocyanate on the metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by cultured rat lung tissue.
    Doerr-O'Rourke K, Trushin N, Hecht SS, Stoner GD.
    Carcinogenesis; 1991 Jun 15; 12(6):1029-34. PubMed ID: 2044181
    [Abstract] [Full Text] [Related]

  • 8. Intestinal metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in rats: Sex difference, inducibility and inhibition by phenethylisothiocyanate.
    Schulze J, Malone A, Richter E.
    Carcinogenesis; 1995 Aug 15; 16(8):1733-40. PubMed ID: 7634397
    [Abstract] [Full Text] [Related]

  • 9. The effect of a 2-h exposure to cigarette smoke on the metabolic activation of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mice.
    Brown BG, Richter E, Tricker AR, Ayres PH, Doolittle DJ.
    Chem Biol Interact; 2001 Nov 28; 138(2):125-35. PubMed ID: 11672696
    [Abstract] [Full Text] [Related]

  • 10. Quantitation of pyridylhydroxybutyl-DNA adducts in liver and lung of F-344 rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
    Upadhyaya P, Kalscheuer S, Hochalter JB, Villalta PW, Hecht SS.
    Chem Res Toxicol; 2008 Jul 28; 21(7):1468-76. PubMed ID: 18570389
    [Abstract] [Full Text] [Related]

  • 11. Analysis of human urine for pyridine-N-oxide metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a tobacco-specific lung carcinogen.
    Carmella SG, Borukhova A, Akerkar SA, Hecht SS.
    Cancer Epidemiol Biomarkers Prev; 1997 Feb 28; 6(2):113-20. PubMed ID: 9037562
    [Abstract] [Full Text] [Related]

  • 12. Biotransformation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in freshly isolated human lung cells.
    Smith GB, Castonguay A, Donnelly PJ, Reid KR, Petsikas D, Massey TE.
    Carcinogenesis; 1999 Sep 28; 20(9):1809-18. PubMed ID: 10469628
    [Abstract] [Full Text] [Related]

  • 13. Analysis of CYP2A contributions to metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human peripheral lung microsomes.
    Brown PJ, Bedard LL, Reid KR, Petsikas D, Massey TE.
    Drug Metab Dispos; 2007 Nov 28; 35(11):2086-94. PubMed ID: 17717079
    [Abstract] [Full Text] [Related]

  • 14. Comparative metabolism of N'-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by cultured F344 rat oral tissue and esophagus.
    Murphy SE, Heiblum R, Trushin N.
    Cancer Res; 1990 Aug 01; 50(15):4685-91. PubMed ID: 2369743
    [Abstract] [Full Text] [Related]

  • 15. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human kidney epithelial cells transfected with rat CYP2B1 cDNA.
    Lacroix D, Desrochers M, Castonguay A, Anderson A.
    Carcinogenesis; 1993 Aug 01; 14(8):1639-42. PubMed ID: 8353848
    [Abstract] [Full Text] [Related]

  • 16. Human cervical tissue metabolizes the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, via alpha-hydroxylation and carbonyl reduction pathways.
    Prokopczyk B, Trushin N, Leszczynska J, Waggoner SE, El-Bayoumy K.
    Carcinogenesis; 2001 Jan 01; 22(1):107-14. PubMed ID: 11159748
    [Abstract] [Full Text] [Related]

  • 17. Tumorigenicity and metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol enantiomers and metabolites in the A/J mouse.
    Upadhyaya P, Kenney PM, Hochalter JB, Wang M, Hecht SS.
    Carcinogenesis; 1999 Aug 01; 20(8):1577-82. PubMed ID: 10426810
    [Abstract] [Full Text] [Related]

  • 18. Enzymes involved in the bioactivation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in patas monkey lung and liver microsomes.
    Smith TJ, Liao AM, Liu Y, Jones AB, Anderson LM, Yang CS.
    Carcinogenesis; 1997 Aug 01; 18(8):1577-84. PubMed ID: 9276633
    [Abstract] [Full Text] [Related]

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