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194 related items for PubMed ID: 19409072

  • 1. Pifithrin-alpha decreases the radioprotective efficacy of a Podophyllum hexandrum Himalayan mayapple fraction REC-2006 in HepG2 cells.
    Singh PK, Kumar R, Sharma A, Arora R, Jain SK, Sharma RK.
    Biotechnol Appl Biochem; 2009 Jul 09; 54(1):53-64. PubMed ID: 19409072
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  • 6. Protective efficacy of semi purified fraction of high altitude podophyllum hexandrum rhizomes in lethally irradiated Swiss albino mice.
    Gupta ML, Tyagi S, Flora SJ, Agrawala PK, Choudhary P, Puri SC, Sharma A, Devi M, Haksar A, Qazi GN, Tripathi RP.
    Cell Mol Biol (Noisy-le-grand); 2007 May 30; 53(5):29-41. PubMed ID: 17543231
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  • 7. Pifithrin-α alters p53 post-translational modifications pattern and differentially inhibits p53 target genes.
    Zhu J, Singh M, Selivanova G, Peuget S.
    Sci Rep; 2020 Jan 23; 10(1):1049. PubMed ID: 31974452
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  • 8. Relation between DNA repair, apoptosis and chromosomal aberrations in presence of pifithrin-alpha, an inhibitor of p53.
    Meschini R, Berni A, Ortenzi V, Mancinelli P, Palitti F.
    Mutat Res; 2010 Aug 14; 701(1):92-7. PubMed ID: 20348016
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  • 9. Study on X-ray-induced apoptosis and chromosomal damage in G2 human lymphocytes in the presence of pifithrin-α, an inhibitor of p53.
    Ortenzi V, Meschini R, Berni A, Mancinelli P, Palitti F.
    Mutat Res; 2011 Nov 27; 726(1):29-35. PubMed ID: 21889606
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  • 10. PFT-alpha inhibits antibody-induced activation of p53 and pro-apoptotic signaling in 1-LN prostate cancer cells.
    Misra UK, Pizzo SV.
    Biochem Biophys Res Commun; 2010 Jan 01; 391(1):272-6. PubMed ID: 19913499
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  • 11. Podophyllum hexandrum as a potential botanical supplement for the medical management of nuclear and radiological emergencies (NREs) and free radical-mediated ailments: leads from in vitro/in vivo radioprotective efficacy evaluation.
    Arora R, Chawla R, Dhaker AS, Adhikari M, Sharma J, Singh S, Gupta D, Kumar R, Sharma A, Sharma RK, Tripathi RP.
    J Diet Suppl; 2010 Mar 01; 7(1):31-50. PubMed ID: 22435572
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  • 12. Cytoprotective effect of Podophyllum hexandrum against gamma radiation is mediated via hemopoietic system stimulation and up-regulation of heme-oxygenase-1 and the prosurvival multidomain protein Bcl-2.
    Rajesh A, Sagar R, Singh S, Kumar R, Sharma AK, Prasad J, Singh S, Gupta M, Sharma RK, Puri SC, Krishna B, Siddiqui MS, Lahiri SS, Tripathi RP, Qazi GN.
    Integr Cancer Ther; 2007 Mar 01; 6(1):54-65. PubMed ID: 17351027
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  • 13. Pifithrin-α as a potential cytoprotective agent in radiotherapy: protection of normal tissue without decreasing therapeutic efficacy in glioma cells.
    Sinn B, Schulze J, Schroeder G, Konschak R, Freyer D, Budach V, Tinhofer I.
    Radiat Res; 2010 Nov 01; 174(5):601-10. PubMed ID: 20718603
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  • 14. Pifithrin-alpha protects against DNA damage-induced apoptosis downstream of mitochondria independent of p53.
    Sohn D, Graupner V, Neise D, Essmann F, Schulze-Osthoff K, Jänicke RU.
    Cell Death Differ; 2009 Jun 01; 16(6):869-78. PubMed ID: 19229248
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  • 15. Post-traumatic administration of the p53 inactivator pifithrin-α oxygen analogue reduces hippocampal neuronal loss and improves cognitive deficits after experimental traumatic brain injury.
    Yang LY, Greig NH, Huang YN, Hsieh TH, Tweedie D, Yu QS, Hoffer BJ, Luo Y, Kao YC, Wang JY.
    Neurobiol Dis; 2016 Dec 01; 96():216-226. PubMed ID: 27553877
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  • 16. Inhibition of p53 by pifithrin-alpha reduces myocyte apoptosis and leukocyte transmigration in aged rat hearts following 24 hours of reperfusion.
    Liu P, Xu B, Cavalieri TA, Hock CE.
    Shock; 2008 Nov 01; 30(5):545-51. PubMed ID: 18317410
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  • 17. XPD could suppress growth of HepG2.2.15 and down-regulate the expression of hepatitis B virus x protein through P53 pathway.
    Ding H, Xu JJ, Huang Y, Du FT, Zhang JX.
    Biochem Biophys Res Commun; 2012 Mar 23; 419(4):761-7. PubMed ID: 22387547
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  • 18. Post-trauma administration of the pifithrin-α oxygen analog improves histological and functional outcomes after experimental traumatic brain injury.
    Yang LY, Chu YH, Tweedie D, Yu QS, Pick CG, Hoffer BJ, Greig NH, Wang JY.
    Exp Neurol; 2015 Jul 23; 269():56-66. PubMed ID: 25819102
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  • 19. [Effects of p53 inhibitor-alpha on the proliferation and apoptosis in large intestinal epithelial cells damaged by hyperthermic chemotherapy].
    Zhang AP, Liu BH, Zhang LY, Tong WD, He YJ, Fu T, Luo DL.
    Zhonghua Yi Xue Za Zhi; 2006 Jan 10; 86(2):93-7. PubMed ID: 16620711
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  • 20. Pifithrin-alpha has a p53-independent cytoprotective effect on docosahexaenoic acid-induced cytotoxicity in human hepatocellular carcinoma HepG2 cells.
    Kanno S, Kurauchi K, Tomizawa A, Yomogida S, Ishikawa M.
    Toxicol Lett; 2015 Jan 22; 232(2):393-402. PubMed ID: 25448278
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