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140 related items for PubMed ID: 19409294

  • 1. Fibronectin fragments mediate matrix metalloproteinase upregulation and cartilage damage through proline rich tyrosine kinase 2, c-src, NF-kappaB and protein kinase Cdelta.
    Ding L, Guo D, Homandberg GA.
    Osteoarthritis Cartilage; 2009 Oct; 17(10):1385-92. PubMed ID: 19409294
    [Abstract] [Full Text] [Related]

  • 2. The cartilage chondrolytic mechanism of fibronectin fragments involves MAP kinases: comparison of three fragments and native fibronectin.
    Ding L, Guo D, Homandberg GA.
    Osteoarthritis Cartilage; 2008 Oct; 16(10):1253-62. PubMed ID: 18396067
    [Abstract] [Full Text] [Related]

  • 3. Fibronectin fragment activation of proline-rich tyrosine kinase PYK2 mediates integrin signals regulating collagenase-3 expression by human chondrocytes through a protein kinase C-dependent pathway.
    Loeser RF, Forsyth CB, Samarel AM, Im HJ.
    J Biol Chem; 2003 Jul 04; 278(27):24577-85. PubMed ID: 12730223
    [Abstract] [Full Text] [Related]

  • 4. Fibronectin fragment-induced expression of matrix metalloproteinases is mediated by MyD88-dependent TLR-2 signaling pathway in human chondrocytes.
    Hwang HS, Park SJ, Cheon EJ, Lee MH, Kim HA.
    Arthritis Res Ther; 2015 Nov 12; 17():320. PubMed ID: 26563875
    [Abstract] [Full Text] [Related]

  • 5. Fibronectin fragments and blocking antibodies to alpha2beta1 and alpha5beta1 integrins stimulate mitogen-activated protein kinase signaling and increase collagenase 3 (matrix metalloproteinase 13) production by human articular chondrocytes.
    Forsyth CB, Pulai J, Loeser RF.
    Arthritis Rheum; 2002 Sep 12; 46(9):2368-76. PubMed ID: 12355484
    [Abstract] [Full Text] [Related]

  • 6. Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration.
    Sieg DJ, Ilić D, Jones KC, Damsky CH, Hunter T, Schlaepfer DD.
    EMBO J; 1998 Oct 15; 17(20):5933-47. PubMed ID: 9774338
    [Abstract] [Full Text] [Related]

  • 7. Antisense oligonucleotides to the integrin receptor subunit alpha(5) decrease fibronectin fragment mediated cartilage chondrolysis.
    Homandberg GA, Costa V, Ummadi V, Pichika R.
    Osteoarthritis Cartilage; 2002 May 15; 10(5):381-93. PubMed ID: 12027539
    [Abstract] [Full Text] [Related]

  • 8. Outside-in signaling in the chondrocyte. Nitric oxide disrupts fibronectin-induced assembly of a subplasmalemmal actin/rho A/focal adhesion kinase signaling complex.
    Clancy RM, Rediske J, Tang X, Nijher N, Frenkel S, Philips M, Abramson SB.
    J Clin Invest; 1997 Oct 01; 100(7):1789-96. PubMed ID: 9312179
    [Abstract] [Full Text] [Related]

  • 9. Focal adhesion kinase and mitogen-activated protein kinases are involved in chondrocyte activation by the 29-kDa amino-terminal fibronectin fragment.
    Gemba T, Valbracht J, Alsalameh S, Lotz M.
    J Biol Chem; 2002 Jan 11; 277(2):907-11. PubMed ID: 11677248
    [Abstract] [Full Text] [Related]

  • 10. Extracellular matrix protein fibronectin induces matrix metalloproteinases in human prostate adenocarcinoma cells PC-3.
    Pal S, Ganguly KK, Chatterjee A.
    Cell Commun Adhes; 2013 Oct 11; 20(5):105-14. PubMed ID: 24047237
    [Abstract] [Full Text] [Related]

  • 11. Proline-rich tyrosine kinase 2 and Src kinase signaling transduce monosodium urate crystal-induced nitric oxide production and matrix metalloproteinase 3 expression in chondrocytes.
    Liu R, Lioté F, Rose DM, Merz D, Terkeltaub R.
    Arthritis Rheum; 2004 Jan 11; 50(1):247-58. PubMed ID: 14730623
    [Abstract] [Full Text] [Related]

  • 12. Telopeptides of type II collagen upregulate proteinases and damage cartilage but are less effective than highly active fibronectin fragments.
    Guo D, Ding L, Homandberg GA.
    Inflamm Res; 2009 Mar 11; 58(3):161-9. PubMed ID: 19190855
    [Abstract] [Full Text] [Related]

  • 13. Arg-Gly-Asp-Ser peptide analogs suppress cartilage chondrolytic activities of integrin-binding and nonbinding fibronectin fragments.
    Homandberg GA, Hui F.
    Arch Biochem Biophys; 1994 Apr 11; 310(1):40-8. PubMed ID: 8161219
    [Abstract] [Full Text] [Related]

  • 14. Hyaluronic acid suppresses fibronectin fragment mediated cartilage chondrolysis: I. In vitro.
    Homandberg GA, Hui F, Wen C, Kuettner KE, Williams JM.
    Osteoarthritis Cartilage; 1997 Sep 11; 5(5):309-19. PubMed ID: 9497938
    [Abstract] [Full Text] [Related]

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  • 17. Fibronectin fragment mediated cartilage chondrolysis. I. Suppression by anti-oxidants.
    Homandberg GA, Hui F, Wen C.
    Biochim Biophys Acta; 1996 Nov 15; 1317(2):134-42. PubMed ID: 8950199
    [Abstract] [Full Text] [Related]

  • 18. Fibronectin fragments elevate nitric oxide (NO) and inducible NO synthetase (iNOS) levels in bovine cartilage and iNOS inhibitors block fibronectin fragment mediated damage and promote repair.
    Pichika R, Homandberg GA.
    Inflamm Res; 2004 Aug 15; 53(8):405-12. PubMed ID: 15316672
    [Abstract] [Full Text] [Related]

  • 19. NOD2 signaling pathway is involved in fibronectin fragment-induced pro-catabolic factor expressions in human articular chondrocytes.
    Hwang HS, Lee MH, Choi MH, Kim HA.
    BMB Rep; 2019 Jun 15; 52(6):373-378. PubMed ID: 30760380
    [Abstract] [Full Text] [Related]

  • 20. Association of proteoglycan degradation with catabolic cytokine and stromelysin release from cartilage cultured with fibronectin fragments.
    Homandberg GA, Hui F.
    Arch Biochem Biophys; 1996 Oct 15; 334(2):325-31. PubMed ID: 8900407
    [Abstract] [Full Text] [Related]

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