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Journal Abstract Search

402 related items for PubMed ID: 19411846

  • 1. The transcription-independent mitochondrial p53 program is a major contributor to nutlin-induced apoptosis in tumor cells.
    Vaseva AV, Marchenko ND, Moll UM.
    Cell Cycle; 2009 Jun 01; 8(11):1711-9. PubMed ID: 19411846
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  • 2. Molecular mechanisms of nutlin-induced apoptosis in multiple myeloma: evidence for p53-transcription-dependent and -independent pathways.
    Saha MN, Jiang H, Chang H.
    Cancer Biol Ther; 2010 Sep 15; 10(6):567-78. PubMed ID: 20595817
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  • 4. Activation of the p53 pathway by the MDM2 inhibitor nutlin-3a overcomes BCL2 overexpression in a preclinical model of diffuse large B-cell lymphoma associated with t(14;18)(q32;q21).
    Drakos E, Singh RR, Rassidakis GZ, Schlette E, Li J, Claret FX, Ford RJ, Vega F, Medeiros LJ.
    Leukemia; 2011 May 15; 25(5):856-67. PubMed ID: 21394100
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  • 6. Mouse double minute antagonist Nutlin-3a enhances chemotherapy-induced apoptosis in cancer cells with mutant p53 by activating E2F1.
    Ambrosini G, Sambol EB, Carvajal D, Vassilev LT, Singer S, Schwartz GK.
    Oncogene; 2007 May 24; 26(24):3473-81. PubMed ID: 17146434
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  • 9. Elevated MDM2 boosts the apoptotic activity of p53-MDM2 binding inhibitors by facilitating MDMX degradation.
    Xia M, Knezevic D, Tovar C, Huang B, Heimbrook DC, Vassilev LT.
    Cell Cycle; 2008 Jun 01; 7(11):1604-12. PubMed ID: 18520179
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  • 10. Blockade of Hsp90 by 17AAG antagonizes MDMX and synergizes with Nutlin to induce p53-mediated apoptosis in solid tumors.
    Vaseva AV, Yallowitz AR, Marchenko ND, Xu S, Moll UM.
    Cell Death Dis; 2011 May 12; 2(5):e156. PubMed ID: 21562588
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  • 14. Disruption of the MDM2-p53 interaction strongly potentiates p53-dependent apoptosis in cisplatin-resistant human testicular carcinoma cells via the Fas/FasL pathway.
    Koster R, Timmer-Bosscha H, Bischoff R, Gietema JA, de Jong S.
    Cell Death Dis; 2011 Apr 21; 2(4):e148. PubMed ID: 21509038
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  • 15. Restoration of p53 pathway by nutlin-3 induces cell cycle arrest and apoptosis in human rhabdomyosarcoma cells.
    Miyachi M, Kakazu N, Yagyu S, Katsumi Y, Tsubai-Shimizu S, Kikuchi K, Tsuchiya K, Iehara T, Hosoi H.
    Clin Cancer Res; 2009 Jun 15; 15(12):4077-84. PubMed ID: 19509161
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  • 16. MDM2 antagonist can inhibit tumor growth in hepatocellular carcinoma with different types of p53 in vitro.
    Wang J, Zheng T, Chen X, Song X, Meng X, Bhatta N, Pan S, Jiang H, Liu L.
    J Gastroenterol Hepatol; 2011 Feb 15; 26(2):371-7. PubMed ID: 21261729
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  • 17. Inhibition of p53-murine double minute 2 interaction by nutlin-3A stabilizes p53 and induces cell cycle arrest and apoptosis in Hodgkin lymphoma.
    Drakos E, Thomaides A, Medeiros LJ, Li J, Leventaki V, Konopleva M, Andreeff M, Rassidakis GZ.
    Clin Cancer Res; 2007 Jun 01; 13(11):3380-7. PubMed ID: 17545546
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  • 18. Nutlin-3 induces HO-1 expression by activating JNK in a transcription-independent manner of p53.
    Choe YJ, Lee SY, Ko KW, Shin SJ, Kim HS.
    Int J Oncol; 2014 Mar 01; 44(3):761-8. PubMed ID: 24366007
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  • 19. MDMX overexpression prevents p53 activation by the MDM2 inhibitor Nutlin.
    Hu B, Gilkes DM, Farooqi B, Sebti SM, Chen J.
    J Biol Chem; 2006 Nov 03; 281(44):33030-5. PubMed ID: 16905541
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  • 20. p53-mediated apoptosis of CLL cells: evidence for a transcription-independent mechanism.
    Steele AJ, Prentice AG, Hoffbrand AV, Yogashangary BC, Hart SM, Nacheva EP, Howard-Reeves JD, Duke VM, Kottaridis PD, Cwynarski K, Vassilev LT, Wickremasinghe RG.
    Blood; 2008 Nov 01; 112(9):3827-34. PubMed ID: 18682598
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