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202 related items for PubMed ID: 19413965

  • 1. Interactions of H562 in the S5 helix with T618 and S621 in the pore helix are important determinants of hERG1 potassium channel structure and function.
    Lees-Miller JP, Subbotina JO, Guo J, Yarov-Yarovoy V, Noskov SY, Duff HJ.
    Biophys J; 2009 May 06; 96(9):3600-10. PubMed ID: 19413965
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  • 4. An intracellular hydrophobic nexus critical for hERG1 channel slow deactivation.
    Stevens-Sostre WA, Flores-Aldama L, Bustos D, Li J, Morais-Cabral JH, Delemotte L, Robertson GA.
    Biophys J; 2024 Jul 16; 123(14):2024-2037. PubMed ID: 38219015
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  • 5. Hydrophobic interactions between the voltage sensor and pore mediate inactivation in Kv11.1 channels.
    Perry MD, Wong S, Ng CA, Vandenberg JI.
    J Gen Physiol; 2013 Sep 16; 142(3):275-88. PubMed ID: 23980196
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  • 6. A single amino acid difference between ether-a-go-go- related gene channel subtypes determines differential sensitivity to a small molecule activator.
    Perry M, Sanguinetti MC.
    Mol Pharmacol; 2008 Apr 16; 73(4):1044-51. PubMed ID: 18162604
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  • 7. Interactions between voltage sensor and pore domains in a hERG K+ channel model from molecular simulations and the effects of a voltage sensor mutation.
    Colenso CK, Sessions RB, Zhang YH, Hancox JC, Dempsey CE.
    J Chem Inf Model; 2013 Jun 24; 53(6):1358-70. PubMed ID: 23672495
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  • 9. The pore domain outer helix contributes to both activation and inactivation of the HERG K+ channel.
    Ju P, Pages G, Riek RP, Chen PC, Torres AM, Bansal PS, Kuyucak S, Kuchel PW, Vandenberg JI.
    J Biol Chem; 2009 Jan 09; 284(2):1000-8. PubMed ID: 18996846
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  • 12. Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator.
    Perry M, Sachse FB, Sanguinetti MC.
    Proc Natl Acad Sci U S A; 2007 Aug 21; 104(34):13827-32. PubMed ID: 17693551
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  • 14. The neutral, hydrophobic isoleucine at position I521 in the extracellular S4 domain of hERG contributes to channel gating equilibrium.
    Dou Y, Goodchild SJ, Velde RV, Wu Y, Fedida D.
    Am J Physiol Cell Physiol; 2013 Aug 15; 305(4):C468-78. PubMed ID: 23761630
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  • 15. Molecular coupling in the human ether-a-go-go-related gene-1 (hERG1) K+ channel inactivation pathway.
    Ferrer T, Cordero-Morales JF, Arias M, Ficker E, Medovoy D, Perozo E, Tristani-Firouzi M.
    J Biol Chem; 2011 Nov 11; 286(45):39091-9. PubMed ID: 21908602
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  • 17. A highly conserved alanine in the S6 domain of the hERG1 K+ channel is required for normal gating.
    Brown S, Sonntag DP, Sanguinetti MC.
    Cell Physiol Biochem; 2008 Nov 11; 22(5-6):601-10. PubMed ID: 19088442
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  • 19. Probing the outer mouth structure of the HERG channel with peptide toxin footprinting and molecular modeling.
    Tseng GN, Sonawane KD, Korolkova YV, Zhang M, Liu J, Grishin EV, Guy HR.
    Biophys J; 2007 May 15; 92(10):3524-40. PubMed ID: 17293393
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