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316 related items for PubMed ID: 19417143

  • 1. Imatinib blocks migration and invasion of medulloblastoma cells by concurrently inhibiting activation of platelet-derived growth factor receptor and transactivation of epidermal growth factor receptor.
    Abouantoun TJ, MacDonald TJ.
    Mol Cancer Ther; 2009 May; 8(5):1137-47. PubMed ID: 19417143
    [Abstract] [Full Text] [Related]

  • 2. Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells.
    Abouantoun TJ, Castellino RC, MacDonald TJ.
    J Neurooncol; 2011 Jan; 101(2):215-26. PubMed ID: 20524040
    [Abstract] [Full Text] [Related]

  • 3. Selective inhibition of PDGFR by imatinib elicits the sustained activation of ERK and downstream receptor signaling in malignant glioma cells.
    Dong Y, Jia L, Wang X, Tan X, Xu J, Deng Z, Jiang T, Rainov NG, Li B, Ren H.
    Int J Oncol; 2011 Feb; 38(2):555-69. PubMed ID: 21152856
    [Abstract] [Full Text] [Related]

  • 4. Increased sensitivity to the platelet-derived growth factor (PDGF) receptor inhibitor STI571 in chemoresistant glioma cells is associated with enhanced PDGF-BB-mediated signaling and STI571-induced Akt inactivation.
    Servidei T, Riccardi A, Sanguinetti M, Dominici C, Riccardi R.
    J Cell Physiol; 2006 Jul; 208(1):220-8. PubMed ID: 16575905
    [Abstract] [Full Text] [Related]

  • 5. Imatinib mesylate inhibits cell invasion of malignant peripheral nerve sheath tumor induced by platelet-derived growth factor-BB.
    Aoki M, Nabeshima K, Koga K, Hamasaki M, Suzumiya J, Tamura K, Iwasaki H.
    Lab Invest; 2007 Aug; 87(8):767-79. PubMed ID: 17558420
    [Abstract] [Full Text] [Related]

  • 6. Imatinib mesylate inhibits the proliferation-stimulating effect of human lung cancer-associated stromal fibroblasts on lung cancer cells.
    Kinoshita K, Nakagawa K, Hamada J, Hida Y, Tada M, Kondo S, Moriuchi T.
    Int J Oncol; 2010 Oct; 37(4):869-77. PubMed ID: 20811709
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of platelet-derived growth factor receptor phosphorylation by STI571 (Gleevec) reduces growth and metastasis of human pancreatic carcinoma in an orthotopic nude mouse model.
    Hwang RF, Yokoi K, Bucana CD, Tsan R, Killion JJ, Evans DB, Fidler IJ.
    Clin Cancer Res; 2003 Dec 15; 9(17):6534-44. PubMed ID: 14695158
    [Abstract] [Full Text] [Related]

  • 8. Imatinib mesylate stimulates low-density lipoprotein receptor-related protein 1-mediated ERK phosphorylation in insulin-producing cells.
    Fred RG, Boddeti SK, Lundberg M, Welsh N.
    Clin Sci (Lond); 2015 Jan 15; 128(1):17-28. PubMed ID: 24865476
    [Abstract] [Full Text] [Related]

  • 9. Imatinib as a key inhibitor of the platelet-derived growth factor receptor mediated expression of cell surface heparan sulfate proteoglycans and functional properties of breast cancer cells.
    Malavaki CJ, Roussidis AE, Gialeli C, Kletsas D, Tsegenidis T, Theocharis AD, Tzanakakis GN, Karamanos NK.
    FEBS J; 2013 May 15; 280(10):2477-89. PubMed ID: 23374223
    [Abstract] [Full Text] [Related]

  • 10. Imatinib mesylate inhibits platelet-derived growth factor activity and increases chemosensitivity in feline vaccine-associated sarcoma.
    Katayama R, Huelsmeyer MK, Marr AK, Kurzman ID, Thamm DH, Vail DM.
    Cancer Chemother Pharmacol; 2004 Jul 15; 54(1):25-33. PubMed ID: 15108021
    [Abstract] [Full Text] [Related]

  • 11. Platelet-derived growth factor expression and function in idiopathic pulmonary arterial hypertension.
    Perros F, Montani D, Dorfmüller P, Durand-Gasselin I, Tcherakian C, Le Pavec J, Mazmanian M, Fadel E, Mussot S, Mercier O, Hervé P, Emilie D, Eddahibi S, Simonneau G, Souza R, Humbert M.
    Am J Respir Crit Care Med; 2008 Jul 01; 178(1):81-8. PubMed ID: 18420966
    [Abstract] [Full Text] [Related]

  • 12. Imatinib mesylate (Gleevec) inhibits ovarian cancer cell growth through a mechanism dependent on platelet-derived growth factor receptor alpha and Akt inactivation.
    Matei D, Chang DD, Jeng MH.
    Clin Cancer Res; 2004 Jan 15; 10(2):681-90. PubMed ID: 14760091
    [Abstract] [Full Text] [Related]

  • 13. Imatinib mesylate and AMN107 inhibit PDGF-signaling in orbital fibroblasts: a potential treatment for Graves' ophthalmopathy.
    van Steensel L, Paridaens D, Schrijver B, Dingjan GM, van Daele PL, van Hagen PM, van den Bosch WA, Drexhage HA, Hooijkaas H, Dik WA.
    Invest Ophthalmol Vis Sci; 2009 Jul 15; 50(7):3091-8. PubMed ID: 19234339
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of platelet-derived growth factor-mediated proliferation of osteosarcoma cells by the novel tyrosine kinase inhibitor STI571.
    McGary EC, Weber K, Mills L, Doucet M, Lewis V, Lev DC, Fidler IJ, Bar-Eli M.
    Clin Cancer Res; 2002 Nov 15; 8(11):3584-91. PubMed ID: 12429650
    [Abstract] [Full Text] [Related]

  • 15. Effect of imatinib mesylate on neuroblastoma tumorigenesis and vascular endothelial growth factor expression.
    Beppu K, Jaboine J, Merchant MS, Mackall CL, Thiele CJ.
    J Natl Cancer Inst; 2004 Jan 07; 96(1):46-55. PubMed ID: 14709738
    [Abstract] [Full Text] [Related]

  • 16. Inhibition of platelet-derived growth factor receptor signaling restricts the growth of human breast cancer in the bone of nude mice.
    Lev DC, Kim SJ, Onn A, Stone V, Nam DH, Yazici S, Fidler IJ, Price JE.
    Clin Cancer Res; 2005 Jan 01; 11(1):306-14. PubMed ID: 15671560
    [Abstract] [Full Text] [Related]

  • 17. Effects of blocking platelet-derived growth factor-receptor signaling in a mouse model of experimental prostate cancer bone metastases.
    Uehara H, Kim SJ, Karashima T, Shepherd DL, Fan D, Tsan R, Killion JJ, Logothetis C, Mathew P, Fidler IJ.
    J Natl Cancer Inst; 2003 Mar 19; 95(6):458-70. PubMed ID: 12644539
    [Abstract] [Full Text] [Related]

  • 18. Imatinib mesylate inhibits platelet-derived growth factor receptor phosphorylation of melanoma cells but does not affect tumorigenicity in vivo.
    McGary EC, Onn A, Mills L, Heimberger A, Eton O, Thomas GW, Shtivelband M, Bar-Eli M.
    J Invest Dermatol; 2004 Feb 19; 122(2):400-5. PubMed ID: 15009722
    [Abstract] [Full Text] [Related]

  • 19. Clinical and molecular studies of the effect of imatinib on advanced aggressive fibromatosis (desmoid tumor).
    Heinrich MC, McArthur GA, Demetri GD, Joensuu H, Bono P, Herrmann R, Hirte H, Cresta S, Koslin DB, Corless CL, Dirnhofer S, van Oosterom AT, Nikolova Z, Dimitrijevic S, Fletcher JA.
    J Clin Oncol; 2006 Mar 01; 24(7):1195-203. PubMed ID: 16505440
    [Abstract] [Full Text] [Related]

  • 20. Differential effects of imatinib on PDGF-induced proliferation and PDGF receptor signaling in human arterial and venous smooth muscle cells.
    Li L, Blumenthal DK, Masaki T, Terry CM, Cheung AK.
    J Cell Biochem; 2006 Dec 15; 99(6):1553-63. PubMed ID: 16817200
    [Abstract] [Full Text] [Related]

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