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Journal Abstract Search

442 related items for PubMed ID: 19421144

  • 1. Myosin-interacting guanine exchange factor (MyoGEF) regulates the invasion activity of MDA-MB-231 breast cancer cells through activation of RhoA and RhoC.
    Wu D, Asiedu M, Wei Q.
    Oncogene; 2009 Jun 04; 28(22):2219-30. PubMed ID: 19421144
    [Abstract] [Full Text] [Related]

  • 2. Intramolecular interactions between the Dbl homology (DH) domain and the carboxyl-terminal region of myosin II-interacting guanine nucleotide exchange factor (MyoGEF) act as an autoinhibitory mechanism for the regulation of MyoGEF functions.
    Wu D, Jiao M, Zu S, Sollecito CC, Jimenez-Cowell K, Mold AJ, Kennedy RM, Wei Q.
    J Biol Chem; 2014 Dec 05; 289(49):34033-48. PubMed ID: 25336641
    [Abstract] [Full Text] [Related]

  • 3. Rho isoform-specific interaction with IQGAP1 promotes breast cancer cell proliferation and migration.
    Casteel DE, Turner S, Schwappacher R, Rangaswami H, Su-Yuo J, Zhuang S, Boss GR, Pilz RB.
    J Biol Chem; 2012 Nov 02; 287(45):38367-78. PubMed ID: 22992742
    [Abstract] [Full Text] [Related]

  • 4. Myosin II-interacting guanine nucleotide exchange factor promotes bleb retraction via stimulating cortex reassembly at the bleb membrane.
    Jiao M, Wu D, Wei Q.
    Mol Biol Cell; 2018 Mar 01; 29(5):643-656. PubMed ID: 29321250
    [Abstract] [Full Text] [Related]

  • 5. RhoA and RhoC have distinct roles in migration and invasion by acting through different targets.
    Vega FM, Fruhwirth G, Ng T, Ridley AJ.
    J Cell Biol; 2011 May 16; 193(4):655-65. PubMed ID: 21576392
    [Abstract] [Full Text] [Related]

  • 6. XPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC.
    Arthur WT, Ellerbroek SM, Der CJ, Burridge K, Wennerberg K.
    J Biol Chem; 2002 Nov 08; 277(45):42964-72. PubMed ID: 12221096
    [Abstract] [Full Text] [Related]

  • 7. Hyaluronan-CD44 interaction promotes c-Src-mediated twist signaling, microRNA-10b expression, and RhoA/RhoC up-regulation, leading to Rho-kinase-associated cytoskeleton activation and breast tumor cell invasion.
    Bourguignon LY, Wong G, Earle C, Krueger K, Spevak CC.
    J Biol Chem; 2010 Nov 19; 285(47):36721-35. PubMed ID: 20843787
    [Abstract] [Full Text] [Related]

  • 8. Divergence of Rho residue 43 impacts GEF activity.
    Sloan CM, Quinn CV, Peters JP, Farley J, Goetzinger C, Wernli M, DeMali KA, Ellerbroek SM.
    Small GTPases; 2012 Nov 19; 3(1):15-22. PubMed ID: 22673745
    [Abstract] [Full Text] [Related]

  • 9. The SmgGDS splice variant SmgGDS-558 is a key promoter of tumor growth and RhoA signaling in breast cancer.
    Hauser AD, Bergom C, Schuld NJ, Chen X, Lorimer EL, Huang J, Mackinnon AC, Williams CL.
    Mol Cancer Res; 2014 Jan 19; 12(1):130-42. PubMed ID: 24197117
    [Abstract] [Full Text] [Related]

  • 10. Anti-RhoA and anti-RhoC siRNAs inhibit the proliferation and invasiveness of MDA-MB-231 breast cancer cells in vitro and in vivo.
    Pillé JY, Denoyelle C, Varet J, Bertrand JR, Soria J, Opolon P, Lu H, Pritchard LL, Vannier JP, Malvy C, Soria C, Li H.
    Mol Ther; 2005 Feb 19; 11(2):267-74. PubMed ID: 15668138
    [Abstract] [Full Text] [Related]

  • 11. The MLK-related kinase (MRK) is a novel RhoC effector that mediates lysophosphatidic acid (LPA)-stimulated tumor cell invasion.
    Korkina O, Dong Z, Marullo A, Warshaw G, Symons M, Ruggieri R.
    J Biol Chem; 2013 Feb 22; 288(8):5364-73. PubMed ID: 23319595
    [Abstract] [Full Text] [Related]

  • 12. GIPC1 interacts with MyoGEF and promotes MDA-MB-231 breast cancer cell invasion.
    Wu D, Haruta A, Wei Q.
    J Biol Chem; 2010 Sep 10; 285(37):28643-50. PubMed ID: 20634288
    [Abstract] [Full Text] [Related]

  • 13. A novel strategy for specifically down-regulating individual Rho GTPase activity in tumor cells.
    Wang L, Yang L, Luo Y, Zheng Y.
    J Biol Chem; 2003 Nov 07; 278(45):44617-25. PubMed ID: 12939257
    [Abstract] [Full Text] [Related]

  • 14. RhoGDIα-dependent balance between RhoA and RhoC is a key regulator of cancer cell tumorigenesis.
    Giang Ho TT, Stultiens A, Dubail J, Lapière CM, Nusgens BV, Colige AC, Deroanne CF.
    Mol Biol Cell; 2011 Sep 07; 22(17):3263-75. PubMed ID: 21757538
    [Abstract] [Full Text] [Related]

  • 15. "Smart" Nanoparticles Enhance the Cytoplasmic Delivery of Anti-RhoC Silencing RNA and Inhibit the Migration and Invasion of Aggressive Breast Cancer Cells.
    Kaushal N, Durmaz YY, Bao L, Merajver SD, ElSayed ME.
    Mol Pharm; 2015 Jul 06; 12(7):2406-17. PubMed ID: 26020100
    [Abstract] [Full Text] [Related]

  • 16. SmgGDS is a guanine nucleotide exchange factor that specifically activates RhoA and RhoC.
    Hamel B, Monaghan-Benson E, Rojas RJ, Temple BR, Marston DJ, Burridge K, Sondek J.
    J Biol Chem; 2011 Apr 08; 286(14):12141-8. PubMed ID: 21242305
    [Abstract] [Full Text] [Related]

  • 17. Gonadotropin-releasing hormone receptor activates GTPase RhoA and inhibits cell invasion in the breast cancer cell line MDA-MB-231.
    Aguilar-Rojas A, Huerta-Reyes M, Maya-Núñez G, Arechavaleta-Velásco F, Conn PM, Ulloa-Aguirre A, Valdés J.
    BMC Cancer; 2012 Nov 23; 12():550. PubMed ID: 23176180
    [Abstract] [Full Text] [Related]

  • 18. A p27(kip1)-binding protein, p27RF-Rho, promotes cancer metastasis via activation of RhoA and RhoC.
    Hoshino D, Koshikawa N, Seiki M.
    J Biol Chem; 2011 Jan 28; 286(4):3139-48. PubMed ID: 21087931
    [Abstract] [Full Text] [Related]

  • 19. Specific induction of migration and invasion of pancreatic carcinoma cells by RhoC, which differs from RhoA in its localisation and activity.
    Dietrich KA, Schwarz R, Liska M, Grass S, Menke A, Meister M, Kierschke G, Längle C, Genze F, Giehl K.
    Biol Chem; 2009 Oct 28; 390(10):1063-77. PubMed ID: 19642867
    [Abstract] [Full Text] [Related]

  • 20. Diverse roles of guanine nucleotide exchange factors in regulating collective cell migration.
    Zaritsky A, Tseng YY, Rabadán MA, Krishna S, Overholtzer M, Danuser G, Hall A.
    J Cell Biol; 2017 Jun 05; 216(6):1543-1556. PubMed ID: 28512143
    [Abstract] [Full Text] [Related]

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