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481 related items for PubMed ID: 19427871
1. A novel dipeptidyl peptidase-4 inhibitor, alogliptin (SYR-322), is effective in diabetic rats with sulfonylurea-induced secondary failure. Asakawa T, Moritoh Y, Kataoka O, Suzuki N, Takeuchi K, Odaka H. Life Sci; 2009 Jul 17; 85(3-4):122-6. PubMed ID: 19427871 [Abstract] [Full Text] [Related]
3. Pharmacokinetic, pharmacodynamic, and efficacy profiles of alogliptin, a novel inhibitor of dipeptidyl peptidase-4, in rats, dogs, and monkeys. Lee B, Shi L, Kassel DB, Asakawa T, Takeuchi K, Christopher RJ. Eur J Pharmacol; 2008 Jul 28; 589(1-3):306-14. PubMed ID: 18538760 [Abstract] [Full Text] [Related]
4. Antidiabetic effects of dipeptidyl peptidase-IV inhibitors and sulfonylureas in streptozotocin-nicotinamide-induced mildly diabetic mice. Matsuyama-Yokono A, Tahara A, Nakano R, Someya Y, Shiraki K, Hayakawa M, Shibasaki M. Metabolism; 2009 Mar 28; 58(3):379-86. PubMed ID: 19217455 [Abstract] [Full Text] [Related]
5. Alogliptin, a potent and selective dipeptidyl peptidase-IV inhibitor for the treatment of type 2 diabetes. Deacon CF. Curr Opin Investig Drugs; 2008 Apr 28; 9(4):402-13. PubMed ID: 18393107 [Abstract] [Full Text] [Related]
6. Pharmacokinetics, pharmacodynamics, and tolerability of single increasing doses of the dipeptidyl peptidase-4 inhibitor alogliptin in healthy male subjects. Christopher R, Covington P, Davenport M, Fleck P, Mekki QA, Wann ER, Karim A. Clin Ther; 2008 Mar 28; 30(3):513-27. PubMed ID: 18405789 [Abstract] [Full Text] [Related]
7. A novel long acting DPP-IV inhibitor PKF-275-055 stimulates β-cell proliferation resulting in improved glucose homeostasis in diabetic rats. Akarte AS, Srinivasan BP, Gandhi S. Biochem Pharmacol; 2012 Jan 15; 83(2):241-52. PubMed ID: 22015634 [Abstract] [Full Text] [Related]
8. RBx-0597, a potent, selective and slow-binding inhibitor of dipeptidyl peptidase-IV for the treatment of type 2 diabetes. Singh S, Roy S, Sethi S, Benjamin B, Sundaram S, Khanna V, Kandalkar SR, Pal C, Kant R, Patra AK, Rayasam G, Mittra S, Saini KS, Paliwal J, Chugh A, Ahmed S, Sattigeri J, Cliff I, Ray A, Bansal VS, Bhatnagar PK, Davis JA. Eur J Pharmacol; 2011 Feb 10; 652(1-3):157-63. PubMed ID: 20540938 [Abstract] [Full Text] [Related]
11. 7-But-2-ynyl-9-(6-methoxy-pyridin-3-yl)-6-piperazin-1-yl-7,9-dihydro-purin-8-one is a novel competitive and selective inhibitor of dipeptidyl peptidase IV with an antihyperglycemic activity. Yamazaki K, Yasuda N, Inoue T, Nagakura T, Kira K, Shinoda M, Saeki T, Tanaka I. J Pharmacol Exp Ther; 2006 Dec 10; 319(3):1253-7. PubMed ID: 16980568 [Abstract] [Full Text] [Related]
17. Effects of the dipeptidyl peptidase-IV inhibitor ASP8497 on glucose tolerance in animal models of secondary failure. Someya Y, Nakano R, Tahara A, Takasu T, Takeuchi A, Nagase I, Matsuyama-Yokono A, Hayakawa M, Sasamata M, Miyata K, Uchiyama Y. Eur J Pharmacol; 2009 Nov 10; 622(1-3):71-7. PubMed ID: 19766107 [Abstract] [Full Text] [Related]
18. Combining a dipeptidyl peptidase-4 inhibitor, alogliptin, with pioglitazone improves glycaemic control, lipid profiles and beta-cell function in db/db mice. Moritoh Y, Takeuchi K, Asakawa T, Kataoka O, Odaka H. Br J Pharmacol; 2009 Jun 10; 157(3):415-26. PubMed ID: 19371350 [Abstract] [Full Text] [Related]
19. ASP8497 is a novel selective and competitive dipeptidyl peptidase-IV inhibitor with antihyperglycemic activity. Matsuyama-Yokono A, Tahara A, Nakano R, Someya Y, Nagase I, Hayakawa M, Shibasaki M. Biochem Pharmacol; 2008 Jul 01; 76(1):98-107. PubMed ID: 18468582 [Abstract] [Full Text] [Related]